Increasing Housing Capacity of the Rodent Barrier Facility

增加啮齿动物屏障设施的容纳能力

• 批准号: 7852654
• 负责人: GARY L WHITE
• 金额: $ 50万
• 依托单位: UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-06-15 至 2011-06-14
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7852654
• 关键词: Applications Grants; Area; Communicable Diseases; Diabetes Mellitus; Equilibrium; Facility Construction; Faculty; Funding; Grant; Growth; Health Sciences; Housing; Knock-out; Malignant Neoplasms; Mus; Neurosciences; Oklahoma; Population; Positioning Attribute; Rattus; Recruitment Activity; Request for Applications; Research; Resources; Rodent; Time; Transgenic Organisms; United States National Institutes of Health; Universities; Update; Veterinarians; Vision; cost; meetings; programs

DESCRIPTION (provided by applicant): This grant application request funds for the purchase of additional ventilated cage racks to meet the continuing demand for cage space in the new Rodent Barrier Facility (RBF). The Oklahoma University Health Sciences Center (OUHSC) has a total of 53 active grants and 23 pending grants involving rodent programs that benefit greatly from being housed in a barrier facility. The OUHSC has identified four areas of research concentration which includes cancer, diabetes, neurosciences/vision and infectious diseases. Utilization of both transgenic and knockout rodents has necessitated an update in rodent research resource facilities. An NIH C 06 grant partially funded the new Rodent Barrier Facility. The C-06 provided four million dollars in support and the University supplied the balance of the funds for construction of the facility totaling over ten million dollars. The University also funded the purchase of 24 ventilated racks for mice and eight ventilated racks for rats at a cost of $872,000 dollars. Subsequently six additional rat ventilated racks were funded by the University at a cost of $118,000. The administration created and funded an additional full time position for a veterinarian and staff to augment the rodent program. Our population of rodents in the barrier has increased at a rapid pace. This growth is the result of both rederivation of transgenic and knockout rodent colonies and recruitment of new faculty that utilize rodents. Faculty are being recruited to fill 18 new endowed research professorship positions further increasing the need for a larger housing capacity in the RBF.

描述（由申请人提供）：本拨款申请请求资金用于购买额外的通风笼架，以满足新啮齿动物屏障设施 (RBF) 对笼子空间的持续需求。俄克拉荷马大学健康科学中心 (OUHSC) 共有 53 项活跃拨款和 23 项待决拨款，涉及啮齿动物项目，这些项目因安置在屏障设施中而受益匪浅。 OUHSC 确定了四个研究重点领域，包括癌症、糖尿病、神经科学/视觉和传染病。转基因和基因敲除啮齿动物的利用需要更新啮齿动物研究资源设施。 NIH C 06 拨款部分资助了新的啮齿动物屏障设施。 C-06提供了400万美元的支持，大学提供了设施建设资金的余额，总计超过1000万美元。该大学还资助购买了 24 个老鼠通风架和 8 个老鼠通风架，耗资 872,000 美元。随后，大学又资助了 6 个老鼠通风架，耗资 118,000 美元。政府为兽医和工作人员设立并资助了一个额外的全职职位，以加强啮齿动物计划。屏障中的啮齿动物数量迅速增加。这种增长是转基因和基因敲除啮齿动物群体重新衍生以及利用啮齿动物招募新教师的结果。正在招募教员来填补 18 个新的捐赠研究教授职位，进一步增加了 RBF 对更大住房容量的需求。