Histology Core

组织学核心

• 批准号: 7734659
• 负责人: Chi-Chao Chan
• 金额: $ 41.58万
• 依托单位: NATIONAL EYE INSTITUTE
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/7734659
• 关键词: Autopsy; Cells; Childhood; Clinical; Consult; Core Facility; Cytopathology; Diagnosis; Diagnostic; Electrons; Eye; Histology; Image; Immunology; In Vitro; Investigation; Laboratories; Licensing; Microscope; Microscopic; Microscopy; Mission; Office of the Director; Operative Surgical Procedures; Pathology; Process; Research; Research Activity; Research Project Grants; Sampling; Services; Slide; Specimen; Staining method; Stains; Thick; Tissues; Transmission Electron Microscopy; United States National Institutes of Health; human tissue; immunopathology; in vivo; research study; tissue processing; transmission process

The Histology Core of the Immunopathology Section, NEI is a core facility devoted to supporting the histopathological activities of NEI. This consists of accessioning human tissues removed at surgery or autopsy, processing the tissues, preparing and staining slides for microscopy and transmission electron microscopy. Within the NEI, the Histology lab serves the Clinical Branch, Laboratory of Immunology, Laboratories and Units under the Scientific Director Office, Cytopathology, and Ultrastructural and Pediatric Pathology sections as well as the Specialized Diagnostics Unit. During FY08, approximately 3092 tissue blocks were prepared from over 3122 specimens and over 7623 slides were cut and stained. Additionally, the laboratory processed case materials sent for ultrastracture, which produced 1199 electron microscopic images from 112 thick sections and 291 samples. This fiscal year, 163 consult slides over 106 clinical cases were received. Although about 95% of effort is devoted to NEI duties, the Histology Core also performs service of processing eyes and ocular tissues for research projects in NIH and outside NIH by arrangement. This activity is coordinated with the tissue research request function of the NIH Operations.

NEI是免疫病理学部分的组织学核心，是致力于支持NEI的组织病理学活性的核心设施。 这包括在手术或尸检时切除的人体组织，处理组织，制备和染色载玻片，以进行显微镜和透射电子显微镜。 在NEI中，组织学实验室在科学主管办公室，细胞病理学以及超微结构和超微结构和儿科病理学部分以及专门的诊断部门下为临床分支，免疫学，实验室和单位实验室服务。 在08财年期间，从3122个标本中制备了大约3092个组织块，并切割并染色了7623张载玻片。 此外，发送的用于超速折磨的实验室加工案例材料，从112个厚的部分和291个样品中产生了1199个电子显微镜图像。在这个财政年度，收到了106例临床病例的163张咨询幻灯片。 尽管大约95％的努力专门用于NEI职责，但组织学核心还通过安排为NIH和NIH外部的研究项目提供了处理眼睛和眼组织的服务。 该活动与NIH操作的组织研究请求函数协调。