Histopathology Core

组织病理学核心

基本信息

批准号：
8557111
负责人：
Chi-Chao Chan
金额：
$ 59.96万
依托单位：
NATIONAL EYE INSTITUTE
依托单位国家：
美国
项目类别：
财政年份：
资助国家：
美国
起止时间：
至
项目状态：
未结题

项目摘要

The Histopathology Core of the NEI is devoted to supporting the patient care, vision research, and mission of the NEI and other collaborative institutes at the NIH. This consists of processing human tissues (mainly ocular tissues) removed in surgeries and collected at autopsies. The Core grosses the tissues, sections and stains slides for light and/or transmission electron microscopy. The Histopathology Core serves the Clinical Branch and all NEI laboratories under the NEI Intramural Research Program, as well as other NIH institutes, which perform research involving ocular and related tissues. In addition, the Core receives clinical and experimental specimens submitted by clinicians and investigators outside NIH (USA and abroad) for consultation or collaboration. During FY12, the Histopathology Core received and processed approximately 5340 specimens and yielded over 9336 slides stained. Additionally, the laboratory processed case materials sent for ultrastructure, which produced 1683 electron microscopic images. This fiscal year, 113 clinical cases were also received and processed. The patient specimens produced 1139 histological slides and 94 electronic microscopic images. There are over 20 publications that include work performed by the Core. Although about 95% of our effort is devoted to NEI duties, the Histopathology Core also performs services for research projects inside and outside the NIH. The core follows the guidelines for the conduct of research in the intramural research program at the NIH and other standards set by the NIH.

NEI 的组织病理学核心致力于支持患者护理、视力研究以及 NEI 和 NIH 的其他合作机构的使命。这包括处理手术中取出并尸检时收集的人体组织（主要是眼组织）。 Core 对组织、切片和染色载玻片进行粗略观察，以进行光学和/或透射电子显微镜检查。组织病理学核心为临床部门和 NEI 校内研究计划下的所有 NEI 实验室以及其他 NIH 机构提供服务，这些机构进行涉及眼部和相关组织的研究。此外，核心还接收 NIH 以外（美国和国外）的临床医生和研究人员提交的临床和实验标本，以进行咨询或合作。 2012 财年期间，组织病理学核心接收并处理了大约 5340 个标本，并产生了超过 9336 个染色玻片。此外，实验室还处理了送至超微结构的病例材料，产生了 1683 个电子显微图像。本财年还受理并处理了113例临床病例。患者标本产生了 1139 张组织学载玻片和 94 张电子显微图像。有 20 多种出版物包含核心所做的工作。尽管我们大约 95% 的精力致力于 NEI 职责，但组织病理学核心还为 NIH 内外的研究项目提供服务。其核心遵循 NIH 校内研究项目的研究指导方针以及 NIH 制定的其他标准。