Histopathology Core

组织病理学核心

• 批准号: 8938505
• 负责人: Chi-Chao Chan
• 金额: $ 53.92万
• 依托单位: NATIONAL EYE INSTITUTE
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/8938505
• 关键词: Autopsy; Cells; Clinical; Clinical Research; Collaborations; Consult; Consultations; Cytology; Cytology Histology; Diagnosis; Electron Microscopy; Electronics; Electrons; Guidelines; Health Services Research; Histology; Histopathology; Image; Immunoelectron Microscopy; Immunohistochemistry; Institutes; Intramural Research Program; Laboratories; Licensing; Light; Liquid substance; Microscopic; Mission; Operative Surgical Procedures; Patient Care; Patients; Physicians; Process; Publications; Reporting; Research; Research Personnel; Research Project Grants; Services; Slide; Specimen; Staining method; Stains; Time; Tissues; Transmission Electron Microscopy; United States National Institutes of Health; Universities; Vision research; Work; human tissue; molecular pathology; operation; research study; tissue processing; transmission process

The Histopathology Core of the NEI, a CLIA licensed facility, is devoted to supporting the patient care, vision research, and mission of the NEI and other collaborative institutes at the NIH. This consists of processing human tissues (mainly ocular tissues) removed in surgeries and collected at autopsies. The Core grosses the tissues, sections and stains slides for light and/or transmission electron microscopy. The Core also performs cytology examination of ocular fluids. The Histopathology Core serves the Clinical Branch and all NEI laboratories under the NEI Intramural Research Program, as well as other NIH institutes, which conduct research involving ocular and related tissues and fluids. In addition, the Core receives clinical and experimental specimens submitted by clinicians and investigators outside NIH (USA and abroad) for diagnosis, consultation or collaboration. During FY14, the Histopathology Core received and processed approximately 4044 specimens and yielded over 5100 slides stained. Additionally, the laboratory processed case materials sent for ultrastructure, which produced 3717 electron microscopic images. This fiscal year, 65 clinical cases were also received and processed. The patient specimens produced 1722 histological slides and 115 electronic microscopic images. There are over 20 publications that include work performed by the Core. Although about 95% of our effort is devoted to NEI duties, the Histopathology Core also performs services for research projects from other institutes, universities, physicians and researchers inside and outside the NIH. The core follows the guidelines for the conduct of research in the intramural research program at the NIH and other standards set by the NIH.

NEI 的组织病理学核心是 CLIA 许可的机构，致力于支持 NEI 和 NIH 的其他合作机构的患者护理、视力研究和使命。这包括处理手术中取出并尸检时收集的人体组织（主要是眼组织）。 Core 对组织、切片和染色载玻片进行粗略观察，以进行光学和/或透射电子显微镜检查。核心还对眼液进行细胞学检查。组织病理学核心为临床部门和 NEI 校内研究计划下的所有 NEI 实验室以及其他 NIH 机构提供服务，这些机构开展涉及眼部和相关组织和液体的研究。此外，核心还接收 NIH 以外（美国和国外）的临床医生和研究人员提交的临床和实验标本，用于诊断、咨询或合作。 2014 财年，组织病理学核心接收并处理了大约 4044 个标本，并产生了 5100 多张染色玻片。此外，实验室还处理了送至超微结构的病例材料，产生了 3717 张电子显微图像。本财年还受理并处理了65例临床病例。患者标本产生了 1722 张组织学载玻片和 115 张电子显微图像。有 20 多种出版物包含核心所做的工作。尽管我们大约 95% 的精力致力于 NEI 职责，但组织病理学核心还为 NIH 内外其他研究所、大学、医生和研究人员的研究项目提供服务。其核心遵循 NIH 校内研究项目的研究指导方针以及 NIH 制定的其他标准。