Histology Core

组织学核心

• 批准号: 7970112
• 负责人: Chi-Chao Chan
• 金额: $ 36.31万
• 依托单位: NATIONAL EYE INSTITUTE
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/7970112
• 关键词: Autopsy; Cells; Clinical; Collaborations; Consult; Core Facility; Diagnosis; Electrons; Eye; Histology; Image; In Vitro; Institutes; Intramural Research Program; Laboratories; Licensing; Microscope; Microscopic; Microscopy; Mission; Operative Surgical Procedures; Process; Research; Research Activity; Research Project Grants; Sampling; Services; Slide; Specimen; Staining method; Stains; Thick; Tissues; Transmission Electron Microscopy; United States National Institutes of Health; human tissue; in vivo; research study; tissue processing; transmission process

The Histology Core of the NEI devotes to supporting the histopathological activities of NEI and other collaborative institutes at the NIH. This consists of accessioning human tissues removed at surgery and autopsy, processing the tissues, preparing and staining slides for microscopy and transmission electron microscopy. Within the NEI, the Histology lab serves the Clinical Branch and all NEI Laboratories and Units under the NEI intramural research program, as well as other NIH institutes, which perform research involving ocular tissues. During FY09, approximately 3266 tissue blocks were prepared from over 6232 specimens and over 6497 slides were cut and stained. Additionally, the laboratory processed case materials sent for ultrastracture, which produced 455 electron microscopic images from 69 thick sections and 60 samples. This fiscal year, 488 consult slides over 96 clinical cases were received. Although about 90% of effort is devoted to NEI duties, the Histology Core also performs service of processing eyes and ocular tissues for research projects inside NIH and outside NIH by collaborations and arrangements. This activity is coordinated with the tissue research request function of the NIH Operations.

NEI 的组织学核心致力于支持 NEI 和 NIH 的其他合作机构的组织病理学活动。 这包括加入在手术和尸检中取出的人体组织、处理组织、制备用于显微镜和透射电子显微镜的载玻片并对其进行染色。 在 NEI 内，组织学实验室为临床部门、NEI 校内研究计划下的所有 NEI 实验室和单位以及其他 NIH 机构提供服务，这些机构进行涉及眼组织的研究。 2009 财年期间，从超过 6232 个样本中制备了大约 3266 个组织块，并对超过 6497 个载玻片进行了切割和染色。 此外，实验室还处理了送至超微结构的案例材料，从 69 个厚切片和 60 个样本中生成了 455 张电子显微镜图像。 本财年，共收到 96 个临床病例的 488 张咨询幻灯片。 尽管大约 90% 的精力致力于 NEI 职责，但组织学核心还通过合作和安排为 NIH 内部和外部的研究项目提供眼睛和眼组织的处理服务。 这项活动与 NIH 运营部门的组织研究请求职能相协调。