Histopathology Core

组织病理学核心

基本信息

批准号：
8339820
负责人：
Chi-Chao Chan
金额：
$ 39.51万
依托单位：
NATIONAL EYE INSTITUTE
依托单位国家：
美国
项目类别：
财政年份：
资助国家：
美国
起止时间：
至
项目状态：
未结题

项目摘要

The Histopathology Core of the NEI is devoted to supporting the patient care, vision research, and mission of the NEI and other collaborative institutes at the NIH. This consists of processing human tissues (mainly ocular tissues) that were removed in surgeries and collected at autopsies. The Core grosses the tissues, sections and stains slides for light and/or transmission electron microscopy. Within the NEI, the Histopathology Core serves the Clinical Branch and all NEI laboratories under the NEI Intramural Research Program, as well as other NIH institutes, which perform research involving ocular and related tissues. In addition, the Core receives clinical and experimental specimens submitted by clinicians and investigators outside NIH (USA and abroad) for consultation. During FY11, approximately 3994 tissue blocks were prepared from over 7780 specimens and over 9534 slides were cut and stained. Additionally, the laboratory processed case materials sent for ultrastructure, which produced 2004 electron microscopic images from 1893 thick sections and 314 samples. This fiscal year, 757 consultation specimens including 118 clinical cases as of August 14, 2011 were also received and processed. Although about 95% of our effort is devoted to NEI duties, the Histopathology Core also performs services for research projects inside and outside the NIH. The core follows the guidelines for the conduct of research in the intramural research program at the NIH and other standards set by the NIH.

NEI 的组织病理学核心致力于支持患者护理、视力研究以及 NEI 和 NIH 的其他合作机构的使命。这包括处理在手术中切除并在尸检中收集的人体组织（主要是眼组织）。 Core 对组织、切片和染色载玻片进行粗略观察，以进行光学和/或透射电子显微镜检查。在 NEI 内，组织病理学核心为临床部门和 NEI 校内研究计划下的所有 NEI 实验室以及其他 NIH 机构提供服务，这些机构进行涉及眼部和相关组织的研究。此外，核心还接收 NIH 以外（美国和国外）的临床医生和研究人员提交的临床和实验标本以供咨询。 2011 财年，我们从 7780 多个标本中制备了大约 3994 个组织块，并对超过 9534 个载玻片进行了切割和染色。此外，实验室还处理了送至超微结构的案例材料，从 1893 个厚切片和 314 个样品中生成了 2004 年电子显微图像。截至2011年8月14日，本财年还收到并处理了757份会诊标本，其中包括118例临床病例。尽管我们大约 95% 的精力致力于 NEI 职责，但组织病理学核心还为 NIH 内外的研究项目提供服务。其核心遵循 NIH 校内研究项目的研究指导方针以及 NIH 制定的其他标准。