Smoking Machine Adaptor Design Project for ENDS, Cigars, and Heated Tobacco Products (UC2)

适用于 ENDS、雪茄和加热烟草产品的吸烟机适配器设计项目 (UC2)

• 批准号: 10214769
• 负责人: Marielle Cavanaugh Brinkman
• 金额: $ 199.54万
• 依托单位: OHIO STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-12-01 至 2025-11-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10214769
• 关键词: Smoking; Machine; Adaptor; Design; Project

ABSTRACT The purpose of the smoking machine adaptor design project is to develop a standardized and validated adaptor, or family of adaptors, for attachment to existing smoking and vaping machines to ensure the accuracy and reliability of scientific data obtained from the study of the physical and chemical properties of electronic nicotine delivery systems (ENDS), cigars, and heated tobacco products (HTPs). Equally important, the project will produce a set of protocols for the generation and collection of mainstream yield data for these four product types. For the proposed research efforts, the Ohio State University (prime contractor) will collaborate closely with the Food and Drug Administration’s Center for Tobacco Products (CTP), and with our proposed team members, including our Particle and Aerosol Characterization Laboratory, the Centers for Disease Control and Prevention Tobacco Products Laboratory (CDC-TPL); our smoking and vaping machine industry partner, Cerulean; and former Borgwaldt KC USA linear smoking machine design implementation engineer, Jeremy Jones, President, Produced Better. The project is comprised of four main phases: 1) Feasibility, 2) Prototype Design and Testing, 3) Adaptor Validation, and 4) Continued Stakeholder Support. Once the validation of the adaptors is complete, our team will be responsible for the manufacture, sale, and continued device support, including continuous design improvement, of the USMA in the final phase of the project and after CTP sponsorship has concluded. The project will provide a public benefit by ensuring that stakeholders can generate accurate scientific data and reduce measurement variability to help fill current scientific gaps regarding the chemical and physical properties of ENDS, cigars, and HTPs. These data will assist FDA in their mission to protect Americans from tobacco-related death and disease by regulating tobacco products and by educating the public, especially young people, about tobacco products and the dangers their use poses to themselves and others.

抽象的 吸烟机适配器设计项目的目的是开发一个标准化且经过验证的 适配器或适配器系列，用于连接到现有吸烟机和电子烟机以确保准确性 电子物理和化学特性研究中获得的科学数据的可靠性和可靠性 尼古丁输送系统（ENDS）、雪茄和加热烟草产品（HTP）同样重要。 将制定一套协议，用于生成和收集这四种产品的主流良率数据 对于拟议的研究工作，俄亥俄州立大学（主承包商）将密切合作。 与美国食品和药物管理局烟草制品中心 (CTP) 以及我们提议的团队合作 成员，包括我们的颗粒和气溶胶表征实验室、疾病控制中心和 预防烟草产品实验室 (CDC-TPL)；我们的吸烟和电子烟机行业合作伙伴， Cerulean；以及前 Borgwaldt KC USA 线性吸烟机设计实施工程师 Jeremy Jones，《制作更好》总裁。该项目由四个主要阶段组成：1) 可行性，2) 原型。 设计和测试，3) 适配器验证，以及 4) 持续的利益相关者支持。 适配器完成后，我们的团队将负责制造、销售和持续的设备支持， 包括 USMA 在项目最后阶段和 CTP 之后的持续设计改进 该项目将通过确保利益相关者能够提供公共利益。 生成准确的科学数据并减少测量变异性，以帮助填补当前的科学空白 有关 ENDS、雪茄和 HTP 的化学和物理特性这些数据将有助于 FDA 的评估。 使命是通过监管烟草产品和通过 教育公众，特别是年轻人，了解烟草制品及其使用对健康造成的危险 他们自己和他人。