Administrative Core

行政核心

• 批准号: 10863409
• 负责人: Martin Lindquist
• 金额: $ 1.23万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-01 至 2027-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10863409
• 关键词: Acute; Benchmarking; Clinical; Collaborations; Communication; Communities; Data; Data Analyses; Data Collection; Effectiveness; Enrollment; Environment; Evaluation; Funding; Goals; Individual; Infrastructure; Lead; Leadership; Maintenance; Measures; Monitor; Patients; Personnel Management; Principal Investigator; Productivity; Recurrence; Reporting; Research; Research Personnel; Research Support; Resources; Schedule; Services; Site; Structure; Translations; United States National Institutes of Health; Universities; Update; Vision; Work; biosignature; chronic pain; clinical center; clinical research site; cost effectiveness; data centers; data integration; data quality; data resource; data submission; design; experience; meetings; member; operation; outreach; programs; response; sound; statistics; success; virtual; working group

In response to RFA-RM-18-031, we will establish a “Data Center for Acute to Chronic Pain Biosignatures” at Johns Hopkins University (JHU). The Center will serve as the Data Integration and Resource Center (DIRC) for the Common Fund Acute to Chronic Pain Signatures (A2CPS) Program. The Center will consist of three components and an Administrative Core (AC). The AC will be led by the Principal Investigators, Martin Lindquist and Tor Wager, with support from a steering committee consisting of the leadership of the various components of the Center and external consultants with significant experience with leading large-scale multisite projects. The AC will oversee and manage the Center components, including fiscal management; personnel management; scheduling and organization of meetings; and maintenance of resources. The AC will also be responsible for facilitating communication and interaction between the components of the Center, as well as with the Clinical Coordinating Center, Multisite Clinical Centers, Omics Data Generating Centers, and NIH staff. It will: (1) reduce administrative barriers across the A2CPS consortium by providing management resources; (2) facilitate presentation of consortium results to the broader scientific community; (3) serve as a central hub for organizing recurring A2CPS consortium meetings, including both face-to-face and virtual meetings; (4) provide regular quantitative updates on enrollment, patient assessments, data deposition, data quality, and data usage statistics, both to the NIH and to other members of the A2CPS consortium; and (5) maintain access to the necessary infrastructure for accomplishing the specific aims of Center, including research, collaboration, and dissemination. Overall, the AC will promote a stimulating intellectual environment to knit researchers involved in A2CPS activities into a strong interdisciplinary community.

为了响应RFA-RM-18-031，我们将建立一个“急性到慢性的数据中心 约翰·霍普金斯大学（JHU）的疼痛生物签名”。该中心将作为 通用基金急性到慢性的数据集成和资源中心（DIRC） 疼痛签名（A2CPS）程序。该中心将由三个组成部分和一个组成 行政核心（AC）。 AC将由主要调查员马丁领导 Lindquist和Tor Wager在指导委员会的支持下由 中心各个组成部分和外部顾问的领导 在领先的大规模多站点项目方面的重要经验。交流将监督 并管理中心组件，包括财政管理；人员 管理;会议安排和组织；和资源维护。 AC还将负责促进 中心的组成部分以及临床协调中心多站点 临床中心，OMICS数据生成中心和NIH员工。它将：（1）减少 通过提供管理 资源; （2）促进财团结果向更广泛的科学呈现 社区; （3）用作组织重复A2CPS联盟的中心枢纽 会议，包括面对面和虚拟会议； （4）提供常规 有关入学率，患者评估，数据沉积，数据质量的定量更新， NIH和A2CPS的其他成员的数据使用统计信息和数据使用统计信息 财团； （5）维护访问完成必要的基础架构 中心的具体目标，包括研究，协作和传播。 总体而言，AC将促进刺激的智力环境来编织研究人员 参与A2CP的活动进入一个强大的跨学科社区。