Predoctoral Training in Multifaceted Translational Approach to Mental Illness
精神疾病多方面转化方法的博士前培训
基本信息
- 批准号:10628129
- 负责人:
- 金额:$ 8.4万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2023
- 资助国家:美国
- 起止时间:2023-06-01 至 2028-05-31
- 项目状态:未结题
- 来源:
- 关键词:
项目摘要
Mental disorders are among the most common causes of disability, and the disease burden is among the highest
of all illnesses. Thus, there is an urgent need to develop not only novel therapeutic approaches but also the next
generation of research scientists who can meet the challenges of the growing field of mental health research.
The overarching goal of this “Predoctoral Training in a Multifaceted Translational Approach to Mental Illness
(AMI)” program (Adrienne Lahti, MD, and Yogesh Dwivedi, PhD as Directors) is to provide the students with an
environment of cross-cultural training where they will be exposed to the clinical challenges, biological
mechanisms, and cutting-edge research approaches used across mental illnesses, rather than the kind of single-
disease training they might obtain by working in an individual research laboratory. The AMI T32 training program
will uniquely provide an interdisciplinary training environment that will integrate basic and translational research
training of predoctoral students to foster the development of critical thinking, communication, and in-depth
research skills. Built on a strong foundation and supported by a large infrastructure of outstanding basic,
translational, and multidisciplinary programs in mental health research, the AMI training program will take
advantage of interdisciplinary mental health research investigative efforts led by strong, internationally renowned
clinical and educational resources within the UAB Department of Psychiatry, dynamic mental health research
efforts by the Comprehensive Neuroscience Center, university-wide interdisciplinary initiatives of the UAB
Depression and Suicide Center, the Comprehensive Center for Translational Sciences, and UAB graduate
programs within the thematically based Graduate Biomedical Sciences and the Psychology Doctoral Program
affiliated with the Department of Psychology. The collaborative environment at UAB, embodied by various cores,
centers, programs, and departments, will provide extensive support for invigorating research efforts. The training
program is requesting three predoctoral training slots per year and will take advantage of well-established best
practices for the successful recruitment of underrepresented minorities and individuals with disabilities. The plan
will include required didactic courses, laboratory and clinical research, journal clubs, seminars, scientific
presentations both locally and at national meetings, and training in the responsible conduct of research. Trainees
will also benefit from courses on grant writing and professional skills development. Together, the trainee and
mentoring team will craft an individual development plan. Internal and External Advisory Committees will
evaluate the overall performance of the AMI training program. A series of benchmarks for progress will be
formulated for each trainee and mentor and reviewed on a semi-annual basis. As a top 25 NIH-funded academic
medical center with state-of-the-art scientific core facilities and university-wide, interdisciplinary research centers,
the University of Alabama at Birmingham is remarkably well-positioned to cultivate a new generation of
translational scientists who will advance and transform mental health research.
精神疾病是残疾最常见的原因之一,伯恩疾病是最高的
在所有疾病中。那迫切需要不仅需要开发新型的治疗方法,而且还需要开发
可以应对心理健康研究领域挑战的研究科学家的产生。
这种“在多方面转化方法中的培训中培训前培训的总体目标
(AMI)”计划(马里兰州Adrienne Lahti和Yogesh Dwivedi,博士学位)是为学生提供
跨文化培训的环境将面临临床挑战,生物学
机制和精神疾病中使用的尖端研究方法,而不是一种单一的
他们可能通过在个别研究实验室工作而获得的疾病训练。 AMI T32培训计划
将独特提供跨学科的培训环境,该环境将整合基本和翻译的研究
培训前学生的培训,以促进批判性思维,沟通和深入的发展
研究技能。建立在强大的基础上,并得到了巨大的基础架构的支持
心理健康研究中的翻译和多学科计划,AMI培训计划将进行
跨学科的心理健康研究调查工作的优势,由强,国际知名的
UAB精神病学系内的临床和教育资源,动态心理健康研究
综合神经科学中心的努力,UAB的大学范围跨学科计划
抑郁和自杀中心,综合转化科学中心和UAB毕业生
基于理论的研究生生物医学科学和心理学博士课程中的计划
隶属于心理学系。 UAB的协作环境,由各种核心体现,
中心,计划和部门将为振兴研究工作提供广泛的支持。培训
计划每年要求三个术前训练插槽,并将利用公认的最佳
成功招募代表性不足的少数民族和残疾人的实践。计划
将包括所需的教学课程,实验室和临床研究,期刊俱乐部,半货人,科学
在当地和国家会议上的演讲以及负责任的研究进行培训。学员
还将受益于赠款写作和专业技能发展的课程。在一起,实习生和
指导团队将制定个人发展计划。内部和外部咨询委员会将
评估AMI培训计划的整体表现。一系列进步基准将是
为每个学员和精神锻炼,并每半年审查。作为NIH资助的前25名学者
拥有最先进的科学核心设施和跨大学的医学中心,跨学科研究中心,
伯明翰阿拉巴马大学的培养非常好,可以培养新一代
转化科学家将进步并改变心理健康研究。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Yogesh Dwivedi其他文献
Yogesh Dwivedi的其他文献
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{{ truncateString('Yogesh Dwivedi', 18)}}的其他基金
Novel regulatory role of nuclear miRNAs in repatterning the transcriptional and post-transcriptional dynamics in MDD brain
核 miRNA 在重模式 MDD 大脑转录和转录后动态中的新调节作用
- 批准号:
10661760 - 财政年份:2022
- 资助金额:
$ 8.4万 - 项目类别:
Neural-Derived Plasma Exosomal MicroRNAs As Promising Novel Biomarkers for Suicidality and Treatment Outcome in Adolescents
神经源性血浆外泌体 MicroRNA 作为青少年自杀和治疗结果的有前景的新型生物标志物
- 批准号:
10684830 - 财政年份:2022
- 资助金额:
$ 8.4万 - 项目类别:
MicroRNA Correlates of Childhood Maltreatment and Suicidality
MicroRNA 与童年虐待和自杀的相关性
- 批准号:
10394212 - 财政年份:2021
- 资助金额:
$ 8.4万 - 项目类别:
MicroRNA Correlates of Childhood Maltreatment and Suicidality
MicroRNA 与童年虐待和自杀的相关性
- 批准号:
10642884 - 财政年份:2021
- 资助金额:
$ 8.4万 - 项目类别:
Epitranscriptomic Mapping of Novel N6-Adenosine-based RNA Methylation in MDD Brain
MDD 脑中新型 N6-腺苷 RNA 甲基化的表观转录组图谱
- 批准号:
9978955 - 财政年份:2019
- 资助金额:
$ 8.4万 - 项目类别:
Epitranscriptomic Mapping of Novel N6-Adenosine-based RNA Methylation in MDD Brain
MDD 脑中新型 N6-腺苷 RNA 甲基化的表观转录组图谱
- 批准号:
10402779 - 财政年份:2019
- 资助金额:
$ 8.4万 - 项目类别:
Epitranscriptomic Mapping of Novel N6-Adenosine-based RNA Methylation in MDD Brain
MDD 脑中新型 N6-腺苷 RNA 甲基化的表观转录组图谱
- 批准号:
10616780 - 财政年份:2019
- 资助金额:
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Perturbed cell signaling network and suicide neurobiology
扰动的细胞信号网络和自杀神经生物学
- 批准号:
8908050 - 财政年份:2013
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$ 8.4万 - 项目类别:
Perturbed cell signaling network and suicide neurobiology
扰动的细胞信号网络和自杀神经生物学
- 批准号:
9325581 - 财政年份:2013
- 资助金额:
$ 8.4万 - 项目类别:
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