NIA/AA for Institute on Methods and Protocols for Advancement of Clinical Trials in ADRD (NIA/AA IMPACT-AD Course)

NIA/AA ADRD 临床试验推进方法和方案研究所（NIA/AA IMPACT-AD 课程）

• 批准号: 10624324
• 负责人: Joshua Grill
• 金额: $ 42.4万
• 依托单位: UNIVERSITY OF SOUTHERN CALIFORNIA
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-06-01 至 2027-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10624324
• 关键词: Acceleration; Achievement; Active Learning; Address; Alzheimer' s Disease; Alzheimer' s disease related dementia; Alzheimer' s disease therapy; Area; Award; Biological Markers; Biometry; Budgets; Caring; Characteristics; Clinical; Clinical Investigator; Clinical Trials; Communication; Communities; Continuing Education; Development; Diagnosis; Disabled Persons; Disparity population; Diverse Workforce; Education; Elements; Ensure; Ethics; Ethnic Population; Evaluation; Evidence Based Medicine; Evolution; Faculty; Fellowship; Funding; Generations; Geriatrics; Goals; Grant; Hispanic-serving Institution; Historically Black Colleges and Universities; Individual; Informatics; Infrastructure; Instruction; Interdisciplinary Study; Intervention; Knowledge; Lead; Learning; Long-Term Effects; Measures; Medical; Medical Research; Mentors; Mentorship; Methodology; Methods; Minority Groups; Mission; Modernization; Monitor; National Institute on Aging; Neuropsychology; Outcome Study; Participant; Patient Recruitments; Persons; Principal Investigator; Professional Organizations; Protocols documentation; Public Health; Request for Proposals; Research; Research Personnel; Resources; Science; Scientist; Sorting; Source; Structure; Training; Training Programs; United States National Institutes of Health; Woman; aging population; career; clinical care; cohort; design; disadvantaged background; education resources; experience; follow-up; improved; innovation; medical specialist; medical specialties; meetings; multidisciplinary; multimodality; neuropsychopharmacology; next generation; novel; outreach; programs; racial population; recruit; satisfaction; skills; sociodemographics; success; symposium; therapy development; trial design; virtual education; workforce needs

Project Summary There is an urgent need for improved therapies for Alzheimer’s Disease and Related Dementias (ADRD). Critical to the mission to develop treatments for and curb the public health impact of ADRD will be a new generation of ADRD scientists, especially scientists with the unique training and skills necessary to design and perform clinical trials. This training is rarely provided through the traditional course of medical or biostatistical education. Moreover, to develop improved therapies for ADRD, multidisciplinary expertise in clinical trials will be necessary, including medical specialists but also expertise in biostatistics, biomarkers, trial design, participant recruitment, study organization, and trial ethics. This proposal requests support for a first-of-its-kind training program in the essential elements of design and conduct of ADRD trials that will leverage the full infrastructure and expertise of the Alzheimer’s Clinical Trials Consortium (ACTC) and be conducted annually to enable a diverse range of clinicians, scientists and researchers to receive modern and robust training on ADRD clinical trials.

项目概要 迫切需要改进阿尔茨海默病和相关痴呆症 (ADRD) 的治疗方法。 新一代药物将致力于开发 ADRD 治疗方法并遏制其对公共健康的影响。 ADRD 科学家，特别是接受过设计和执行临床所需的独特培训和技能的科学家 这种培训很少通过传统的医学或生物统计教育课程提供。 此外，为了开发 ADRD 的改进疗法，临床试验中的多学科专业知识是必要的， 包括医学专家，还包括生物统计学、生物标志物、试验设计、参与者招募、 该提案请求支持该领域首个此类培训计划。 ADRD 试验的设计和实施的基本要素将利用完整的基础设施和专业知识 阿尔茨海默病临床试验联盟 (ACTC) 每年进行一次，以实现各种不同的临床试验 最受欢迎的科学家和研究人员接受有关 ADRD 临床试验的现代而强大的培训。