Johns Hopkins HIV Epidemiology and Prevention Sciences Training Program

约翰·霍普金斯大学艾滋病流行病学和预防科学培训计划

• 批准号: 10617066
• 负责人: Shruti H Mehta
• 金额: $ 43.85万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-06-01 至 2028-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10617066
• 关键词: Epidemiology; HIV; Prevention; Science; Training Programs

PROJECT SUMMARY / ABSTRACT This proposal is a renewal application for years 11-15 of a 5-year National Research Service Award Institutional Research Grant to support a training program in HIV Epidemiology and Prevention Sciences at the Johns Hopkins Bloomberg School of Public Health (BSPH) and the Johns Hopkins School of Medicine (SOM), entitled the “Johns Hopkins HIV Epidemiology and Prevention Sciences Training Program.” The program will be led by Shruti Mehta PhD, MPH who has been the deputy director of this program for the past 10 years. We are requesting support for 3 pre- and 4 post-doctoral trainees The program mission is to train pre-doctoral students and post-doctoral fellows to become leaders at the forefront of highest priority HIV research with advanced competencies and state-of-the-art skills in three training tracks: 1) HIV Epidemiology and Implementation Science Methods including training in (1) Populations and Study Designs, including identifying, recruiting, and retaining populations relevant for domestic and international HIV research as well as contemporary designs for implementation science; (2) Measurement issues in populations infected with and at risk for HIV, including innovative methods for surveillance, population-based measures of disease burden and mHealth/online strategies for data collection; (3) Inference techniques, including causal inference, mathematical modeling; and (4) Synthesis and Implementation of research findings to practice, including systematic reviews, cost-effectiveness analyses, and barriers to implementation of HIV programs; 2) HIV Clinical and Laboratory Sciences including training in (1) the epidemiology, prevention and management of major co- infections with HIV including hepatitis C virus (HCV) infection, tuberculosis and SARS-CoV-2/COVID-19; (2) epidemiology and pathogenesis of HIV and age-associated co-morbidities; and (3) Measurement and use (e.g., phylodynamics) of genetic, virologic and immunologic factors that can inform our knowledge of the pathogenesis and transmission of HIV; and 3) HIV Prevention Sciences including how to prevent and reduce the prevalence and incidence of HIV through training in (1) Design and Analysis of HIV biomedical, behavioral and integrated strategies for prevention trials, including treatment as prevention research (TasP), PrEP, HIV vaccine and passive immune-therapy trials, and (2) Community-based population-level approaches to HIV prevention and control. Our program, which is fully integrated through the JHU Center for AIDS Research (CFAR) has resulted in a rich and interactive environment for trainees working in HIV augmented by the exceptionally innovative, productive and collaborative HIV research conducted by epidemiological, clinical, prevention and implementation scientists throughout Johns Hopkins BSPH, and SOM.

项目摘要 /摘要 该提案是为期5年的国家研究服务奖11 - 15年的续签申请 机构研究赠款，以支持HIV流行病学和预防科学培训计划 约翰·霍普金斯彭博公共卫生学院（BSPH）和约翰·霍普金斯医学院 （SOM），题为“约翰·霍普金斯艾滋病毒流行病学和预防科学培训计划”。这 计划将由MPH Shruti Mehta博士领导，他曾担任该计划的副主任 10年。我们要求支持3个前和4名博士后学员，计划任务是培训 博士前的学生和博士后研究员成为最高优先艾滋病毒的领导者 具有高级能力和最先进技能的三个培训轨道的研究：1）艾滋病毒流行病学 和实施科学方法，包括（1）种人口和研究设计的培训，包括 识别，招募和保留与国内和国际艾滋病毒研究相关的人群以及 实施科学的当代设计； （2）感染和处于感染的人群的测量问题 艾滋病毒的风险，包括监视的创新方法，基于人群的疾病燃烧措施 MHealth/数据收集的在线策略； （3）推理技术，包括因果推理，数学 造型; （4）综合和实施研究结果，包括系统评价， 成本效益分析和实施艾滋病毒计划的障碍； 2）HIV临床和实验室 科学包括（1）培训（1）流行病学，预防和管理主要共同感染 HIV包括丙型肝炎病毒（HCV）感染，结核病和SARS-COV-2/COVID-19； （2）流行病学和 艾滋病毒的发病机理和与年龄相关的合并症； （3）测量和使用（例如，系统动力学） 遗传，病毒学和免疫学因素，这些因素可以告知我们对发病机理的了解 艾滋病毒的传播； 3）预防艾滋病毒科学，包括如何预防和降低流行率和 通过（1）培训HIV的发病率（1）艾滋病毒生物医学，行为和综合 预防试验策略，包括作为预防研究（TASP），PREP，HIV疫苗和 被动免疫疗法试验以及（2）基于社区的人群预防艾滋病毒和 控制。我们的计划通过JHU艾滋病研究中心（CFAR）完全整合 为在HIV中工作的受训者增强的学员带来了丰富而互动的环境 由流行病学，临床，预防和 Johns Hopkins BSPH和SOM的实施科学家。

项目成果

Impact of Age and Sex on CD4+ Cell Count Trajectories following Treatment Initiation: An Analysis of the Tanzanian HIV Treatment Database.

• DOI: 10.1371/journal.pone.0164148
• 发表时间: 2016
• 期刊: PloS one
• 影响因子: 3.7
• 作者: Means AR;Risher KA;Ujeneza EL;Maposa I;Nondi J;Bellan SE
• 通讯作者: Bellan SE

Marginal Structural Models to Assess Delays in Second-Line HIV Treatment Initiation in South Africa.

• DOI: 10.1371/journal.pone.0161469
• 发表时间: 2016
• 期刊: PloS one
• 影响因子: 3.7
• 作者: Rohr JK;Ive P;Horsburgh CR;Berhanu R;Shearer K;Maskew M;Long L;Sanne I;Bassett J;Ebrahim O;Fox MP
• 通讯作者: Fox MP

Public health and international drug policy.

• DOI: 10.1016/s0140-6736(16)00619-x
• 发表时间: 2016-04-02
• 期刊: Lancet (London, England)
• 作者: Csete J;Kamarulzaman A;Kazatchkine M;Altice F;Balicki M;Buxton J;Cepeda J;Comfort M;Goosby E;Goulão J;Hart C;Kerr T;Lajous AM;Lewis S;Martin N;Mejía D;Camacho A;Mathieson D;Obot I;Ogunrombi A;Sherman S;Stone J;Vallath N;Vickerman P;Zábranský T;Beyrer C
• 通讯作者: Beyrer C

Getting to 90: linkage to HIV care among men who have sex with men and people who inject drugs in India.

• DOI: 10.1080/09540121.2016.1168915
• 发表时间: 2016-10
• 期刊: AIDS care
• 影响因子: 1.7
• 作者: McFall AM;Mehta SH;Srikrishnan AK;Lucas GM;Vasudevan CK;Celentano DD;Kumar MS;Solomon S;Solomon SS
• 通讯作者: Solomon SS

Prevalence and correlates of using opioids alone among individuals in a residential treatment program in Michigan: implications for overdose mortality prevention.

• DOI: 10.1186/s12954-022-00723-4
• 发表时间: 2022-12-03
• 期刊: HARM REDUCTION JOURNAL
• 影响因子: 4.4
• 作者: Gicquelais, Rachel E.;Genberg, Becky L.;Maksut, Jessica L.;Bohnert, Amy S. B.;Fernandez, Anne C.
• 通讯作者: Fernandez, Anne C.