Instrumentation, Fabrication, and Design Core

仪器仪表、制造和设计核心

• 批准号: 10273967
• 负责人: RONALD H SILVERMAN
• 金额: $ 19.12万
• 依托单位: COLUMBIA UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-07-01 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10273967
• 关键词: 3D ultrasound; Behavioral; Blood flow; Collaborations; Core Facility; Custom; Data; Development; Devices; Emergency Situation; Equipment; Eye; Goals; Grant; Home; Human; Implant; Laboratories; Lifting; Mechanics; Modification; Monkeys; Neurosciences; Postdoctoral Fellow; Primates; Rattus; Research Design; Research Personnel; Resources; Science; System; Technology; Time; Training; Universities; Vision research; Visual system structure; design; equipment training; instrument; instrumentation; new technology; prototype; repaired; student training; vision science

Instrumentation and Fabrication Core Resource for Vision Sciences, Ronald Silverman, Core Director Summary/Abstract The long-term goal of the Core is to provide mechanical design and fabrication support for vision research at Columbia, especially that of investigators with RO1 grants and young investigators gathering data for their first successful RO1s. State-of-the-art vision research is dependent upon the development of new technology and the improvement of current technology. The Core supports a specially dedicated machine shop and one machinist. Because the shop is in-house, and the machinist is familiar with demands of vision research, designing new equipment is far more efficient than it would be with a University or commercial shop. The core has four specific aims: 1)To design and build custom equipment necessary for vision research, both systems neuroscience vision research and ophthalmic science. 2)To provide emergency repairs and modifications for equipment currently in use for vision research. 3)To train students and postdoctoral fellows in the most effective ways to collaborate with instrument designers. 4)To encourage collaboration among vision research investigators, having them share ideas for new devices that might be used in multiple laboratories. This is especially important for systems neuroscience vision research, where similar equipment is used to answer vastly different scientific questions. Collaboration in instrument design has often led to scientific collaboration. The Core builds the standard devices used for systems neuroscience such as recording chambers, primate chairs and grids. Although some of these devices are available commercially, the ones built by the Core are far more durable. Examples of custom equipment built by the Core are cage mounted behavioral training systems to train monkeys in their home cage rather than using rig time; a system for lifting a monkey chair to the cage opening to facilitate transfer from the cage to the chair; a 3D ultrasound probe manipulator for blood flow studies in rat eyes. This now successful prototype will be expanded for use in humans.

视觉科学的仪器和制造核心资源， 罗纳德·西尔弗曼（Ronald Silverman），核心导演 摘要/摘要 核心的长期目标是为视觉研究提供机械设计和制造支持 哥伦比亚，尤其是RO1赠款的调查员和年轻调查员收集数据的调查员 第一个成功的RO1。最先进的愿景研究取决于新的发展 技术与当前技术的改进。核心支持专门专用的机器 商店和一名机械师。因为商店是内部的，机械师熟悉视力的需求 研究，设计新设备的效率要比大学或商业广告要高得多 店铺。核心具有四个特定的目标：1）设计和制造视力所需的定制设备 研究，系统神经科学视觉研究和眼科科学。 2）提供紧急情况 当前用于视觉研究的设备进行维修和修改。 3）培训学生和 博士后研究员以最有效的方式与乐器设计师合作。 4）鼓励 视觉研究调查人员之间的合作，让他们分享可能是新设备的想法 用于多个实验室。这对于系统神经科学视觉研究尤其重要 类似的设备用于回答截然不同的科学问题。仪器设计协作 经常导致科学合作。核心构建用于系统神经科学的标准设备 例如录音室，灵长类椅和网格。尽管其中一些设备可用 在商业上，由核心建造的核心要耐用得多。由 核心是笼子安装的行为训练系统，以训练猴子在他们的家笼中而不是使用 钻机时间；将猴子椅子抬到笼子开口的系统，以方便从笼子转移到笼子 椅子;用于大鼠眼中血流研究的3D超声探针操纵器。现在成功的原型 将扩展以供人类使用。