Administrative Core

行政核心

• 批准号: 10271831
• 负责人: JAMES M TAKACS
• 金额: $ 50.03万
• 依托单位: UNIVERSITY OF NEBRASKA LINCOLN
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-08-15 至 2026-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10271831
• 关键词: Advisory Committees; Biochemical Pathway; Biology; Biomedical Research; Cells; Centers of Research Excellence; Chemicals; Collaborations; Communication; Complex; Development; Development Plans; Disease; Disease Pathway; Educational workshop; Ensure; Environment; Evaluation; Faculty; Fostering; Funding; Goals; Grant; Growth; Health; Homeostasis; Individual; Infrastructure; Institution; Interdisciplinary Study; Intervention; Leadership; Life; Mentors; Molecular; Molecular Probes; Nebraska; Outcome; Pathway interactions; Phase; Population; Postdoctoral Fellow; Process; Program Research Project Grants; Regulation; Research; Research Infrastructure; Research Methodology; Research Personnel; Research Project Grants; Research Support; Role; Route; Secure; Seeds; Structure; Talents; Techniques; Technology; Tissues; Training; Travel; United States; Universities; Vision; career development; graduate student; improved; informatics tool; macromolecule; member; novel; operation; organizational structure; prevent; programs; recruit; research and development; success; symposium; therapy development; undergraduate student

PROJECT SUMMARY/ABSTRACT The transfer of information between macromolecules is one of the defining aspects of life at the molecular level and is critical for all homeostatic and disease processes. The Nebraska Center for Integrated Biomolecular Communication (CIBC) fosters interdisciplinary research focused on spatial and temporal aspects of biomolecular communication using approaches that span a continuum ranging from the molecular to the tissue levels. CIBC has significantly increased biomedical research expertise in Nebraska by developing independently funded interdisciplinary research collaborations that are pursuing high impact research into complex diseases from diverse perspectives. The goal of the Administrative Core in Phase 2 is to continue to provide the overall coordination and administrative infrastructure that will enable CIBC to continue growing the interdisciplinary biomedical expertise and approaches needed to understand the regulation of biomedically relevant communication pathways. The specific aims are: 1) provide the scientific, administrative, and programmatic leadership and research infrastructure needed to ensure CIBC operations function effectively and efficiently and support progress toward the Center’s overall goals and specific aims, 2) coordinate a strong mentoring and development plan to catalyze the research and career development of early stage investigators and their transition to independent investigator status, 3) support and expand a suite of Center-wide enrichment activities to create a collaborative research environment, provide meaningful opportunities for CIBC members to interact with one another, and promote a clear pathway by which additional faculty, postdoctoral research associates, and graduate and undergraduate students will affiliate with the Center; and 4) support CIBC’s eventual transition to a self-sustaining center of biomedical research excellence by supporting Center members in securing program project grants; large-scale, multi-investigator grants; individual investigator projects; and training grants. By accomplishing these aims, the Administrative Core will support CIBC’s central goals of 1) supporting the growth of biomedical research infrastructure at the University of Nebraska and 2) advancing the understanding of the regulation of biomedically relevant communication pathways and the development of interventions to detect, prevent, and treat disease, improving health outcomes among the broader population.

项目摘要/摘要 大分子之间的信息传递是分子水平生命的防御性方面 对于所有稳态和疾病过程至关重要。 沟通（CIBC）促进了针对空间和时间方面的跨学科研究 使用跨越分子到tisue的连续体的方法，生物分子通信 CIBC的水平大大提高了内布拉斯加州的生物医学研究专业知识 资助的跨学科研究合作，对复杂的探索进行高影响研究 从不同的角度来看。 协调和行政基础设施将使CIBC能够继续跨学科 生物医学专业知识和方法是了解生物医学相关的调节 沟通途径。 确保CIBC操作功能的功能和有效的领导和研究基础架构需要 支持朝着中心的整体目标和具体目标的进展，2）协调强大的指导和 开发计划促进早期研究人员的研究和职业发展及其职业发展 过渡到独立调查员身份，3）支持和扩展一套中心范围的丰富活动 为了创建协作研究环境，为CIBC成员提供有意义的机会 彼此之间，并宣传了一条明确的途径 毕业生和地下学生将隶属于中心； 4） 通过支持安全计划的中心成员来为卓越生物医学研究的自我维持中心 项目赠款； 实现目标，行政核心将支持CIBC的核心目标1）支持增长 内布拉斯加州大学生物医学研究基础设施和2）促进对 对生物医学相关的沟通途径的规定和国际发展的发展，以检测， 预防和治疗疾病，改善更广泛的人群中的健康状况。