Administrative Core

行政核心

基本信息

批准号：
10016360
负责人：
JAMES M TAKACS
金额：
$ 92.55万
依托单位：
UNIVERSITY OF NEBRASKA LINCOLN
依托单位国家：
美国
项目类别：
财政年份：
2016
资助国家：
美国
起止时间：
2016-08-15 至 2021-09-13
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10016360
关键词：
Award Biochemical Pathway Biomedical Research Cell Communication Cells Cellular Structures Centers of Research Excellence Chemicals Collaborations Communication Communication Research Complex Computer Models Core Facility Coupled Development Development Plans Disease Disease Pathway Ensure Environment Environmental Risk Factor Evaluation Expression Profiling Faculty Fostering Gene Expression Genetic Transcription Genome Goals Grant Health Image Individual Interdisciplinary Study Intervention Leadership Mass Spectrum Analysis Mentors MicroRNAs Molecular Molecular Probes Monitor NMR Spectroscopy Nebraska Nutrient Outcome Pathway interactions Peptide Sequence Determination Pilot Projects Population Postdoctoral Fellow Process Program Research Project Grants Proteins Regulation Research Research Infrastructure Research Methodology Research Personnel Research Support Role Route Structure Students Talents Teacher Professional Development Techniques Technology Tissues Training Travel University resources Vision Visit base career development deep sequencing faculty mentor graduate student improved informatics tool innovation meetings member novel operation organizational structure pathogen prevent programs research and development success undergraduate student voucher

项目摘要

ABSTRACT The Nebraska Center for Integrated Biomolecular Communication (CIBC) will promote and coordinate interdisciplinary research focused on filling fundamental gaps in understanding spatial and temporal aspects of biomolecular communication. The CIBC will embrace approaches that span from the molecular and tissue levels to computational modeling. The CIBC's long-term goal is to leverage existing capabilities in basic biomedical research by fostering the development of integrated, interdisciplinary research teams with broad disciplinary representation to interrogate complex disease pathways from a wide range of perspectives. The CIBC's near-term goal is to support the research efforts and career development of early stage investigators whose research is broadly focused on understanding the regulation of biomedically relevant communication pathways. The interdisciplinary focus of CIBC, coupled with support for two essential research cores facilities, will serve as a natural mixing chamber to encourage new collaborations, especially by connecting researchers developing new molecular probes and analytical techniques with those researching specific disease pathways. The overall goal of the Administrative Core is to contribute to the CIBC's success by leading, implementing, and supporting the Center's primary activities. The four Specific Aims of the Administrative Core are to: 1) Develop and maintain an organizational structure to provide leadership and coordination of CIBC research and related activities; 2) Implement a faculty development and mentoring plan to further the research and career development of early stage investigators and catalyze their transition to independent investigators; 3) Provide enrichment activities for CIBC members to promote membership in the Center and encourage new research collaborations; and 4) Transition from IDeA program support as a self-sustaining center of biomedical research excellence. The Administrative Core defines the roles and responsibilities of the Director and Co-director, two advisory groups, two research core facilities and their directors, and the project leaders' scientific mentors, as well as the criteria for Center membership and selection as project leader. The faculty development and mentoring plan for early stage investigators leverages available university resources and combines them with responsive one-on-one mentoring to create the framework for individual mentoring plans for project leaders. The Administrative Core's enrichment activities will include monthly meetings, support for seminars, an annual Center retreat, travel awards for graduate students and postdoctoral researchers, support for short-term faculty or student visits, a research core voucher program, and support for pilot projects. All Center activities will be monitored by a comprehensive evaluation plan. The Administrative Core will provide the essential structure to support CIBC in the development of novel research methods and cutting-edge bioanalytical and informatics tools to facilitate the study of complex disease, provide a suite of enrichment activities for its members, and chart the route to a self-sustaining center of biomedical research excellence.

抽象的内布拉斯加州综合生物分子通讯中心（CIBC）将促进和协调跨学科研究的重点是填补理解空间和时间方面的基本空白生物分子通讯。 CIBC 将采用从分子到组织的方法水平到计算建模。 CIBC 的长期目标是利用基本业务领域的现有能力通过培养具有广泛知识的综合性、跨学科研究团队来促进生物医学研究学科代表从广泛的角度审视复杂的疾病途径。这 CIBC 的近期目标是支持早期研究人员的研究工作和职业发展其研究广泛集中于理解生物医学相关通讯的调节途径。 CIBC 的跨学科重点，加上对两个重要研究核心设施的支持，将作为一个自然的混合室来鼓励新的合作，特别是通过连接研究人员与研究特定疾病途径的人员一起开发新的分子探针和分析技术。行政核心的总体目标是通过领导、实施、并支持中心的主要活动。行政核心的四个具体目标是： 1) 开发和维护一个组织结构，以领导和协调 CIBC 的研究和相关活动； 2）实施教师发展和指导计划以进一步研究和职业发展培养早期研究人员并促进他们向独立研究人员过渡； 3）提供为 CIBC 会员举办丰富活动，以促进中心会员资格并鼓励新研究合作； 4) 从 IDeA 计划支持转型为自我维持的生物医学研究中心卓越。行政核心定义了董事和联合董事（两位董事）的角色和职责顾问小组、两个研究核心设施及其负责人以及项目负责人的科学导师，例如以及中心成员资格和选拔项目负责人的标准。师资队伍建设及早期研究人员的指导计划利用现有的大学资源并将其与响应式一对一指导，为项目负责人创建个人指导计划框架。行政核心的丰富活动将包括每月会议、支持研讨会、年度会议中心务虚会、研究生和博士后研究人员的旅行奖励、短期教师支持或学生访问、研究核心凭证计划以及对试点项目的支持。所有中心活动将由综合评估计划进行监控。行政核心将提供基本结构支持 CIBC 开发新颖的研究方法以及尖端的生物分析和信息学促进复杂疾病研究的工具，为其成员提供一套丰富的活动，以及规划通往自我维持的卓越生物医学研究中心的路线。