EDGE CMT: Dissecting complex traits in wild isolates of yeast by high-throughput genome editing

EDGE CMT：通过高通量基因组编辑剖析野生酵母分离物的复杂性状

• 批准号: 10559617
• 负责人: Lars M Steinmetz
• 金额: $ 50万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-02-01 至 2026-01-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10559617
• 关键词: Agar; Alleles; Azoles; Bar Codes; Biological Assay; Carbon; Chemicals; Cisplatin; Clinical; Clustered Regularly Interspaced Short Palindromic Repeats; Codon Nucleotides; Collection; Communities; Complex; Data; Data Set; Dependence; Development; Engineering; Environment; Eukaryota; Exhibits; Foundations; Genes; Genetic; Genetic Variation; Genome; Geography; Goals; Growth; Human Cell Line; Individual; Instruction; Investigation; Liquid substance; Measures; Metals; Methotrexate; Minor; Modeling; Nature; Open Reading Frames; Organism; Pathway interactions; Phenotype; Population; Quality Control; Recovery; Robotics; Saccharomyces; Saccharomyces cerevisiae; Sirolimus; Source; Spottings; Stress; System; Technology; Terminator Codon; Testing; Time; Validation; Variant; Yeasts; causal variant; fitness; follow-up; functional genomics; genetic architecture; genetic resource; genetic variant; genome database; genome editing; genome sequencing; human disease; indexing; internal control; loss of function; pathogenic fungus; precision medicine; premature; recombinase; small molecule; trait

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