Emory-CDC CTU

埃默里大学CDC CTU

基本信息

批准号：
10057691
负责人：
Jeffrey Lennox
金额：
$ 313.48万
依托单位：
EMORY UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2007
资助国家：
美国
起止时间：
2007-02-01 至 2027-11-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10057691
关键词：
AIDS prevention AIDS/HIV problem Acquired Immunodeficiency Syndrome Address Adolescent Adult Americas Anti-Retroviral Agents Area Biological Centers for Disease Control and Prevention (U.S.)Childhood Cities Clinic Clinical Research Clinical Trials Clinical Trials Network Clinical Trials Unit Collaborations Complex Conduct Clinical Trials Country Development Disease Disease remission Enrollment Epidemic Funding Grant HIV HIV Infections HIV therapy HIV vaccine HIV/TB Hepatitis Infection Inflammation Institution International Intervention Kenya Latino Malignant Neoplasms Methods Mexico Minority Mission National Institute of Allergy and Infectious Disease Network Infrastructure Opportunistic Infections Organ Pharmaceutical Preparations Philippines Population Population Heterogeneity Positioning Attribute Prevention Prevention strategy Primates Protocols documentation Public Policy Recording of previous events Research Research Activity Research Infrastructure Research Personnel Research Subjects Scientific Advances and Accomplishments Site Social Behavior Strategic Planning Technology Thailand Therapeutic Translating Translational Research Tuberculosis Tuberculosis Vaccines Underrepresented Populations United States National Institutes of Health Universities Vaccines Woman Youth base clinical center clinical implementation clinical research site co-infection comorbidity experience flexibility high risk human subject improved low and middle-income countries member men next generation novel prevent programs recruit success support network therapeutic vaccine treatment strategy tuberculosis treatment vaccine development volunteer working group

项目摘要

Project Summary/Abstract The currently funded Emory-CDC Clinical Trials Unit (Emory-CDC CTU) is ideally positioned to implement the mission of NIAID and to conduct clinical trials developed by the NIH HIV/AIDS Clinical Trials Networks. The Emory-CDC CTU is supported by Emory’s rich scientific milieu with numerous synergistic grants and various thematic research centers covering all network priority areas, as well as the support and experience of our CDC partners. The Emory-CDC CTU is comprised of 5 CRSs with well-established programs and histories of performing NIH funded clinical research. In this renewal the Emory-CDC CTU will be expanding to a 6th CRS in Mexico City. Our specific aims are the following: 1. To contribute scientific expertise and human subject enrollment into studies that address these four key research areas: Adult HIV therapeutic strategies, including HIV cure, noninfectious comorbidities, and the infectious comorbidities of hepatitis and tuberculosis; strategies to address HIV and HIV-associated infections in pediatric and maternal populations; integrated HIV prevention strategies; and vaccines to prevent HIV infection. 2. To be a leading CTU for contributions of women, minorities, and adolescents to support network clinical trials, both domestically and in low and middle-income countries. 3. To operate an efficient and flexible CTU that can respond rapidly to evolving research opportunities. 4. To participate in the development and implementation of the clinical research plans of all the NIAID clinical research networks that are addressing the four priority areas.

项目摘要/摘要当前资助的Emory-CDC临床试验单元（Emory-CDC CTU）理想地定位为执行任务 NIAID并进行NIH HIV/AIDS开发的临床试验临床试验网络。 Emory-CDC CTU得到了Emory丰富的科学环境的支持涵盖所有网络的许多协同赠款和各种主题研究中心优先领域以及我们的CDC合作伙伴的支持和经验。 Emory-CDC CTU完成了5个CRS，具有完善的计划和执行NIH的历史资助的临床研究。在此续订中墨西哥城。我们的具体目的是以下： 1。将科学专业知识和人类主题入学介绍给研究这四个关键研究领域：成人艾滋病毒治疗策略，包括艾滋病毒治疗，非感染的合并症以及肝炎的感染性合并症结核;解决儿科和与艾滋病毒相关感染的策略产妇人群；综合艾滋病毒预防策略；和防止艾滋病毒的疫苗感染。 2。成为妇女，少数族裔和青少年的贡献的领先CTU支持网络临床试验，无论是在国内还是中低收入国家。 3。操作有效且灵活的CTU，可以迅速响应不断发展的研究机会。 4。参与所有人的临床研究计划的制定和实施 NIAID临床研究网络正在解决这四个优先领域。