CTU COVID Testing Supplement

CTU 新冠病毒检测补充资料

• 批准号: 10166198
• 负责人: Jeffrey Lennox
• 金额: $ 59.99万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-06-16 至 2021-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10166198
• 关键词: 2019-nCoV; African American; Age; Area; COVID-19; COVID-19 pandemic; Caring; Case Study; Centers for Disease Control and Prevention (U.S.); Cessation of life; Characteristics; Cities; Clinic; Clinical; Clinical Trials Unit; Communities; Contact Tracing; Coronavirus; Country; County; Data; Diabetes Mellitus; Faculty; HIV; Hospitals; Hypertension; Individual; Infection; Lead; Measures; Medical; Obesity; Outcome; Participant; Patients; Persons; Population; Prevention; Quarantine; Reporting; Research; Research Infrastructure; Research Personnel; Safety; Severe Acute Respiratory Syndrome; Site; Social Distance; Testing; Universities; Vaccines; Virus; clinical research site; co-infection; comorbidity; coronavirus disease; effective therapy; face mask; high risk; interest; mHealth; metropolitan; pandemic disease; patient population; scale up

Emory-CDC Clinical Trials Unit-Supplement for COVID-19 testing Project Summary/Abstract The emerging COVID-19 pandemic, caused by the SARS-Co-V-2 coronavirus has already caused over 1.3 million infections and over 80,000 deaths in the US as of May 13, 2020 (1). In the absence of effective therapies or a vaccine, non-pharmacologic measures such as social distancing, face masks and lockdowns have been implemented for prevention of COVID-19 infection which has helped to decrease the spread. Additional critical measures to control the pandemic include identification and isolation of infected individuals and contact tracing which requires scaling up of testing for all people. As of May 13, 2020, the US has been able to perform ~ 9 million tests, or around 29,000 tests/million population. While this is a large number and, in fact, more tests performed than any other country in the world, it is still not sufficient. Several investigators suggest that 3 – 4 million tests/week are needed in order to test ~ 1% of the US population. Atlanta, Georgia has not been spared by the COVID-19 pandemic. While these is no data available for City of Atlanta, the 5 counties that form the Atlanta metropolitan area (Fulton, DeKalb, Gwinnett, Clayton and Cobb) have reported 11,771 cases which represents 34% of the total cases reported in the State of Georgia (2). The characteristics and clinical outcomes of hospitalized patients with COVID-19 in Georgia have been recently described (3). Among 305 patients, the median age was 60 years with 29% of the patients under the age of 50. Also, 83% were African American and although co-morbid conditions such as diabetes, obesity and hypertension were common, 1 in 4 patients admitted did not have any high-risk conditions. In a study among COVID-19 patients in three hospitals where Emory University faculty provide medical care, 20 of 530 persons had HIV co-infection. Median age was 57 years, most had controlled HIV and comorbid condition such as hypertension and diabetes. The Emory-CDC HIV Clinical Trials Unit has two Clinical Research Sites in Atlanta, the Hope Clinic of the Emory Vaccine Center and the Ponce de Leon Clinic. Both sites offer great opportunities to expand testing, not only to their existing patient populations but also to the neighboring communities. In this application we propose to use the existing infrastructure for research and will add expanded facilities for COVID-19 testing. Since testing for COVID-19 must incorporate safety measures for the staff, we plan to develop expanded facilities including temporary tents to accommodate potential drive through scenarios, and/or a mobile health clinic.

emory-CDC临床试验与19次测试的单位供应 项目摘要/摘要 由SARS-CO-V-2冠状病毒引起的新兴COVID-19大流行已经引起了1.3多次 截至2020年5月13日，美国的百万感染和80,000多人死亡。在没有有效的情况下 疗法或疫苗，非药物措施，例如社交距离，面具和锁定 已经实施了预防COVID-19的感染，这有助于减少蔓延。 控制大流行的其他关键措施包括识别和隔离感染个体 和接触跟踪，需要对所有人进行测试。截至2020年5月13日，美国已经 能够进行约900万次测试，或大约29,000次测试/百万人口。虽然这是一个大数字，并且 事实，比世界上任何其他国家 /地区进行的测试更多，这仍然不够。几个调查人员 建议为了测试约1％的美国人口，需要每周3-400万个测试。 佐治亚州亚特兰大尚未受到19日大流行的遗憾。虽然这些没有可用于城市的数据 亚特兰大，构成亚特兰大大都会地区的5个县（富尔顿，迪卡尔布，格温内特，克莱顿和科布） 已经报告了11,771例病例，占佐治亚州报告总案件的34％（2）。 最近，佐治亚州Covid-19患者的特征和临床结果已最近 描述（3）。在305名患者中，中位年龄为60岁，其中29％的患者在50岁以下。 此外，有83％的非裔美国人，尽管糖尿病，肥胖和诸如糖尿病的疾病 高血压很常见，四分之一的患者承认没有任何高风险状况。在研究中 埃默里大学教职员工提供医疗服务的三家医院的Covid-19患者，530人中有20名 艾滋病毒共感染。中位年龄为57岁，大多数患有艾滋病毒和合并症，例如 高血压和糖尿病。 Emory-CDC HIV临床试验单元在亚特兰大有两个临床研究地点，这是希望的诊所 Emory疫苗中心和Ponce de Leon诊所。这两个站点都提供了扩展测试的绝佳机会， 不仅对他们现有的患者人群，而且针对邻近社区。在此应用中，我们 使用现有基础设施进行研究的建议，并将为Covid-19测试增加扩展的设施。 由于对Covid-19的测试必须纳入员工的安全措施，因此我们计划开发扩展 包括临时租户在内的设施，可容纳在情况下的潜在开车和/或移动健康 诊所。