Deviance proneness and risk for alcohol dependence

异常倾向和酒精依赖风险

• 批准号: 7552542
• 负责人: VICTOR M HESSELBROCK
• 金额: $ 27.05万
• 依托单位: UNIVERSITY OF CONNECTICUT SCH OF MED/DNT
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-12-01 至 2007-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7552542
• 关键词: 19 year old; Adolescence; Age; Age-Years; Alcohol abuse; Alcohol consumption; Alcohol dependence; Alcoholism; Alcohols; Antisocial Personality Disorder; Behavior; Biological; Clinical; Cognitive; Communities; Connecticut; Daily; Data; Data Analyses; Databases; Development; Elements; Ensure; Equation; Ethanol; Ethnic Origin; Etiology; Evaluation; Expectancy; Family; Family Relationship; Family history of; Frequencies; Gender; Gender Relations; Heavy Drinking; Interview; Investigation; Life; Link; Measures; Mediator of activation protein; Mental disorders; Methods; Modeling; Neuropsychology; Neurotransmitters; Numbers; Parents; Personal Satisfaction; Personality Traits; Population; Predisposition; Problem behavior; Process; Recording of previous events; Research; Risk; Risk Factors; Sampling; Social Interaction; Socialization; Staging; Stress; Temperament; Testing; Time; Universities; Variant; Work; alcohol related problem; alcohol research; alcohol use disorder; cognitive function; concept; coping; daily functioning; drinking; drinking behavior; early onset; experience; follow-up; heuristics; male; peer; peer influence; psychologic; psychosocial; skills; trait; university student; young adult

DESCRIPTION (provided by applicant): This application proposes a second five-year follow-up evaluation of a sample of 338 ethnically diverse, young adults (males=148) between the ages of 24-29 years old to examine the 'Deviance Prone' model of vulnerability in relation to predicting several alcohol use behaviors, including pathological involvement. This model posits that a significant aspect of the susceptibility for developing pathological alcohol involvement due to a parental history of alcoholism may result from deficient socialization and problem behavior. Although the Deviance Prone model was originally proposed as a heuristic model to explain the development of pathological alcohol involvement, many elements of the model have also been implicated as predictors of early onset of alcohol use and early heavy use of alcohol. The proposed study builds upon and extends our previous work on conduct problems and antisocial personality disorder with this and other samples. Information on key features of the model were initially collected when subjects were 14-19 years old and again at 19-24 years old. The study is unique in that the sample was ascertained from the community, is ethnically diverse, and has been well characterized using clinical, psychosocial, cognitive, and electrophysiological measures during the two initial assessments; parents were also directly interviewed. Using data from the three different time points, the present proposal will: 1) test the accuracy of the model for predicting different drinking behaviors at three different points in the subjects' lives: in mid-adolescence, in late adolescence, and in young adulthood; 2) examine the influence of age, ethnicity, gender, peer, and family relations, and coping ability as potential mediators/moderators of the Deviance Prone model's ability to predict alcohol use and alcohol problems at these three different time points; and 3) examine the accuracy of the Deviance Prone model for predicting alcohol use behaviors over time. Using structural equation modeling methods, the data collected at baseline and at Time 2 will be used to predict drinking behaviors, including pathological alcohol use, at Time 3. We will also continue our analyses using the baseline data to predict alcohol use behaviors at Time 2. The stability and efficiency of the Deviance Prone model for predicting early initiation of regular alcohol use, heavy regular use, and pathological alcohol involvement at these three different points in time will also be examined.

描述（申请人提供）：本申请提出了第二五年的随访 评估24-29岁年龄段的338个种族多样化的年轻人（男性= 148）的样本，以研究与预测几种酒精使用行为有关的“偏见”模型，包括病理参与。该模型指出，由于酗酒的父母历史，由于社会化和问题行为不足而导致的病理酗酒参与的易感性的重要方面。尽管最初提出了容易发生模型的偏差模型，以解释病理酒精参与的发展，但该模型的许多元素也被视为早期饮酒和早期大量使用酒精的预测指标。拟议的研究基于并扩展了我们先前关于行为问题和反社会人格障碍的工作，并使用此样本进行了反社会人格障碍。最初，当受试者年龄在14-19岁时，并在19-24岁时再次收集有关模型的关键特征的信息。这项研究的独特之处在于，从社区确定样本，是种族多样的，并且在两种初始评估中使用临床，社会心理，认知和电生理学指标表征了很好的特征。父母也直接采访了。使用来自三个不同时间点的数据，目前的建议将：1）测试模型的准确性，以预测受试者生活中三个不同点的不同饮酒行为：在青春期，青春期和成年时期； 2）检查 年龄，种族，性别，同伴和家庭关系，以及应对能力作为偏离模型的潜在调解人/主持人，这些模型容易预测这三个不同时间点酒精使用和酒精问题的能力； 3）检查偏离偏差模型的准确性，以预测随着时间的推移饮酒行为。使用结构方程建模方法，将使用在时间3的基线和时间2收集的数据来预测饮酒行为，包括病理饮酒，在时间3中。我们还将继续使用基线数据进行分析，以预测时间2的酒精使用行为。偏离偏差模型的稳定性和效率，可预测常规酒精的早期使用，并进行了定期的饮酒量，并在三个不同的酒精中进行了差异。