HIV Vaccines, Immunoprophylaxis and Drugs

HIV 疫苗、免疫预防和药物

• 批准号: 10699245
• 负责人: TERRY L. SHEPPARD
• 金额: $ 2.13万
• 依托单位: KEYSTONE SYMPOSIA
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-04-01 至 2024-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10699245
• 关键词: AIDS prevention; Abnormal Cell; Academia; Antibodies; Antigens; Area; Autoimmunity; B-Lymphocytes; Biology of HIV Transmission; COVID-19 prevention; Cellular biology; Clinical Trials; Collaborations; Colorado; Communicable Diseases; Dapivirine; Development; Disease; Educational workshop; Evaluation Studies; Foundations; Future; Government; HIV; HIV Infections; HIV vaccine; HIV-1; Immune; Industry; Infection; Investigation; Knowledge; Learning; Mediating; Mentors; Methodology; Methods; Outcome; Participant; Patients; Pharmaceutical Preparations; Phase; Prevention; Prevention approach; Prevention strategy; Research; Research Personnel; Resolution; Resources; Role; Science; Scientist; Thinking; Update; Vaccination; Vaccine Design; Vaccines; Work; cancer cell; clinical practice; design; effective therapy; efficacy study; immunoprophylaxis; improved; innovation; interest; meetings; method development; multidisciplinary; next generation; novel strategies; novel vaccines; pandemic disease; posters; pre-exposure prophylaxis; preclinical study; prevent; programs; prophylactic; prospective; rapid growth; response; symposium; treatment strategy; vaccination strategy; vaccine development; vaccine efficacy; vaccine platform; vaccine strategy

ABSTRACT Support is requested for a Keystone Symposia conference entitled HIV Vaccines, Immunoprophylaxis and Drugs, organized by Drs. Hanneke Schuitemaker, Steven Deeks and Dennis Burton. The conference will be held in Keystone, Colorado from June 6 - 10, 2023. Despite the availability of effective treatment and prevention strategies, the HIV pandemic continues, with approximately 1.7 million new infections annually. It is critical for there to be more effective prevention strategies. This Keystone Symposia conference will assemble experts on the biology of HIV transmission and emerging prevention methods, including vaccines and pre-exposure prophylaxis (PrEP), in order to discuss the current state-of-the-art in HIV prevention. Specific topics of discussion will include germline vaccination strategies and updates on the vaccine and PrEP efficacy studies. Additionally, the program will cover the challenges and opportunities of developing novel strategies in an era of increasingly effective prevention methods, particularly long-acting PrEP (cabotegravir) and the dapivirine ring, as well as next generation vaccine and PrEP approaches. The role that HIV prevention resources and advances have had on the COVID-19 prevention and HIV cure research agendas will also be discussed, with the hope that these three largely complementary areas of investigation will remain highly synergistic. Finally, this meeting is being held jointly with the Keystone Symposia conference, B Cell Biology in the Context of Infectious Diseases, Autoimmunity and B Cell Cancers. This pairing is ideal to discuss how B cell abnormalities contribute to HIV infection, especially in terms of the potential for antibody-based vaccine development. Participants from both conferences will have the opportunity to network through shared sessions, mealtimes, and evening poster sessions.

抽象的 请求支持Keystone研讨会会议，标题为艾滋病毒疫苗，免疫预防和 药物，由Drs组织。 Hanneke Schuitemaker，Steven Deeks和Dennis Burton。会议将是 于2023年6月6日至10日在科罗拉多州的基斯通举行。 尽管有有效的治疗和预防策略，但艾滋病毒大流行仍在继续 每年大约有170万个新感染。对于更有效的预防至关重要 策略。这次Keystone研讨会会议将汇集有关HIV传播生物学的专家 新兴预防方法，包括疫苗和暴露前预防（PREP），以讨论 当前预防艾滋病毒的最新。讨论的具体主题将包括种系疫苗接种 疫苗和准备功效研究的策略和更新。此外，该程序将涵盖 在日益有效的预防时代，制定新策略的挑战和机遇 方法，尤其是长效准备（Cabotegravir）和Dapivirine环，以及下一代 疫苗和准备方法。艾滋病毒预防资源和进步在 还将讨论COVID-19预防和HIV治疗研究议程，希望这三个 在很大程度上，互补的调查领域将保持高度协同作用。最后，举行了这次会议 与Keystone研讨会会议共同，在传染病的背景下B细胞生物学， 自身免疫性和B细胞癌。这种配对是讨论B细胞异常如何促成HIV的理想选择 感染，特别是在基于抗体的疫苗开发的潜力方面。两者的参与者 会议将有机会通过共享的会议，进餐时间和晚间海报进行联网 会议。