Multipotent stem cells derived from postimplantation mouse embryos: Evaluation of germ layer differentiation potential

来自植入后小鼠胚胎的多能干细胞：胚层分化潜力的评估

• 批准号: nhmrc : 632776
• 负责人: Prof Patrick Tam
• 金额: $ 52.6万
• 依托单位: The University of Sydney
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2010
• 资助国家: 澳大利亚
• 起止时间: 2010-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/multipotent-stem-cells-differentiation-potential/95131
• 关键词: Multipotent; stem; cells; derived; postimplantation

This study of the properties of cells that can differentiate into specific lineages provides useful insights into the cellular and molecular mechanisms for the specification of these progenitors from the pluripotent stem cells. The procurement of tissue-specific precursor cells that are capable of self-renewing and population expansion is a critical pre-requisite for achieving directed differentiation of stem cells into therapeutically useful cells for tissue replacement and regeneration.

这项对可分化为特定谱系的细胞特性的研究为了解多能干细胞分化这些祖细胞的细胞和分子机制提供了有用的见解。获得能够自我更新和群体扩张的组织特异性前体细胞是实现干细胞定向分化为用于组织替代和再生的治疗有用细胞的关键先决条件。