CSHL 2010 Conference on Molecular Genetics and Bacteria & Phages

CSHL 2010 分子遗传学和细菌会议

基本信息

批准号：
8005291
负责人：
DAVID J. STEWART
金额：
$ 1.85万
依托单位：
COLD SPRING HARBOR LABORATORY
依托单位国家：
美国
项目类别：
财政年份：
2010
资助国家：
美国
起止时间：
2010-07-01 至 2011-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8005291
关键词：
Address Animals Area Bacteria Bacteriophages Biochemistry Biotechnology Cell physiology Cells Chairperson Cheese Cholera Communicable Diseases Development Ecology Ecosystem Environment Gene Expression Genetic Genetic Transcription Genomics Heat shock proteins Human Immunity Individual International Laboratories Life Life Cycle Stages Literature Metabolism Metagenomics Molecular Molecular Genetics Nature Participant Pathogenesis Planets Plants Postdoctoral Fellow Process Research Scanning Scientist Sea Senior Scientist Signal Transduction Soil Students Syphilis Systems Analysis Text Translations Tuberculosis Universities Virus Wisconsin Work abstracting biological adaptation to stress graduate student meetings microorganism posters protein folding recombinational repair response structural biology symposium tool

Address Animals Area Bacteria Bacteriophages Biochemistry Biotechnology Cell physiology Cells Chairperson Cheese Cholera Communicable Diseases Development Ecology Ecosystem Environment Gene Expression Genetic Genetic Transcription Genomics Heat shock proteins Human Immunity Individual International Laboratories Life Life Cycle Stages Literature Metabolism Metagenomics Molecular Molecular Genetics Nature Participant Pathogenesis Planets Plants Postdoctoral Fellow Process Research Scanning Scientist Sea Senior Scientist Signal Transduction Soil Students Syphilis Systems Analysis Text Translations Tuberculosis Universities Virus Wisconsin Work abstracting biological adaptation to stress graduate student meetings microorganism posters protein folding recombinational repair response structural biology symposium tool

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项目摘要

DESCRIPTION (provided by applicant): Abstract PI: STEWART, DAVID J. Project: 1R13AI091053-01 Title: CSHL 2010 Conference on Molecular Genetics and Bacteria & Phages Accession Number: 3254930 ================== NOTICE: THIS ABSTRACT WAS EXTRACTED FROM APPLICATION AND HAS NOT BEEN PROOFED BY AN SRA.WHEN THERE ARE PROBLEMS WITH THE APPLICATION SCANNING PROCESS, THE EXTRACTED TEXT MAY BE INCORRECT OR INCOMPLETE. ================== COLD SPRING HARBOR LABORATORY CONFERENCE ON THE MOLECULAR GENETICS OF BACTERIA AND PHAGES AUGUST 24 - 28, 2010 PROJECT SUMMARY The Molecular Genetics of Bacteria and Phages Conference, traditionally held at Cold Spring Harbor and now being held in alternate years at the University of Wisconsin in Madison and at the Cold Spring Harbor Laboratory, is a central forum for the presentation of new results in prokaryotic molecular genetics. On the order of 200-400 participants attend, representing laboratories throughout the world, and most present either short talks or posters. Its breadth makes it an important focus for the exchange of information in this era of scientific specialization. Topics covered include fundamental work on bacterial replication, recombination, repair, transposition, transcription, control of gene expression, translation, signaling, heat shock, protein folding and secretion, stress response, cell development and division, and pathogenesis. In recent years, efforts have been made to include emerging areas such as genomics and metagenomics, sociomicrobiology, molecular ecology, structural biology and systems analysis. For many graduate students and postdoctoral fellows, this is the first large meeting at which they have an opportunity to speak. Due to its highly interactive nature, the meeting provides an important opportunity for these young scientists to meet and talk to the senior scientists they know from the literature. In response to the large numbers of students who attend the meeting and the diversity of topics covered, established and distinguished scientists are invited to chair each session. This strengthens the meeting because each chairperson gives a short introduction in which he or she summarizes some of the key facets of the field to be covered and provides a conceptual framework for the major questions that the talks will address. As an additional benefit, publicizing the judiciously chosen chairpeople and session topics in announcements of the meeting encourages the submission of abstracts in exciting new areas and stimulates attendance by a larger constituency. COLD SPRING HARBOR LABORATORY CONFERENCE ON THE MOLECULAR GENETICS OF BACTERIA AND PHAGES AUGUST 24 - 28, 2010 LAY STATEMENT The unicellular microorganisms known as bacteria can be found in almost all ecosystems on the planet, from extreme environments to the human gut. Humans have evolved robust immunity to live alongside many bacteria, and indeed to use bacteria in processes from cheese-making to biotechnology, but under adverse conditions, bacteria are responsible for many important infectious diseases such as tuberculosis, cholera or syphilis. Much as plants and animals have viruses, so bacteria can be infected by bacteriophages that alter their metabolism and biochemistry. Phages have been used by scientists for many decades as exquisite genetic tools to probe many fundamental aspects of the molecular machinery at work in bacteria. This work has helped us to understand how bacteria control their life cycle, how cells reproduce and divide, and how they survive in and sense their environment. Research is now shifting from how individual bacterial cells function to how colonies of microorganisms collaborate and survive, and how these colonies adapt to changes in their environment, in niches as varied as in the soil, under the sea, or in an animal or human host. This international conference will provide a forum for scientists working on related topics to share their latest discoveries and will bring together the leading experts in the field.

描述（由申请人提供）：抽象的 PI：Stewart，David J.项目：1R13AI091053-01标题：CSHL 2010年分子遗传学和细菌和噬菌体登录号：3254930 =================== 注意：此摘要是从应用程序中提取的，尚未由SRA证明。当应用程序扫描过程存在问题时，提取的文本可能不正确或不完整。 =================== 冷春港实验室大会细菌分子遗传学和噬菌体会议2010年8月24日至28日，项目总结细菌和噬菌体会议的分子遗传学，传统上在冷春港举行，现在在麦迪逊大学的威斯康星大学在麦迪逊大学和冷春港大学的替代年份举行，是对新遗传学的核心论坛。根据200-400名参与者的命令，代表世界各地的实验室，大多数人都在短暂的谈判或海报。它的广度使其成为在这个科学专业时代交换信息的重要重点。涵盖的主题包括细菌复制，重组，修复，换位，转录，控制基因表达，翻译，信号传导，热休克，蛋白质折叠和分泌，压力反应，细胞发育和分裂以及发病机理的基本工作。近年来，已经做出了努力，包括基因组学和宏基因组学，社会生物学，分子生态学，结构生物学和系统分析等新兴领域。对于许多研究生和博士后研究员来说，这是他们有机会讲话的第一次大型会议。由于其高度互动性的性质，会议为这些年轻科学家提供了一个重要的机会，可以与他们从文献中认识的高级科学家见面和交谈。为了回应参加会议的众多学生以及涵盖，建立和杰出科学家的主题的多样性。这加强了会议，因为每个主席都简要介绍了他或她总结了要涵盖的领域的一些关键方面，并为会谈将解决的主要问题提供了一个概念框架。为了额外的好处，在会议公告中宣传明智选择的主席和会议主题，鼓励在令人兴奋的新领域提交摘要，并通过更大的选区刺激出席。冷春港实验室关于细菌和噬菌体分子遗传学和噬菌体的实验室会议，2010年8月24日至28日，在地球上的几乎所有生态系统中，从极端环境到人类肠道。人类已经发展出强大的免疫力，可以与许多细菌一起生活，并且实际上是在从奶酪制作到生物技术的过程中使用细菌，但是在不利条件下，细菌是导致许多重要的感染性疾病（例如结核，霍乱或梅毒）。就像动植物具有病毒一样，细菌可以被噬菌体感染，这些噬菌体会改变其新陈代谢和生物化学。科学家已经将噬菌体用作精美的遗传工具，以探测细菌工作中分子机械的许多基本方面。这项工作帮助我们了解了细菌如何控制其生命周期，细胞如何繁殖和分裂以及它们如何在环境中生存并感知环境。现在，研究正在从单个细菌细胞的功能如何转变为微生物的菌落如何合作和生存，以及这些菌落如何适应其环境变化，在土壤，海底或动物或人类或人类宿主中的壁ni。这次国际会议将为研究相关主题的科学家提供一个论坛，以分享其最新发现，并将该领域的领先专家汇集在一起。