New GORDON RESEARCH CONFERENCE: Advanced Cell and Tissue Biomanufacturing: Technology Development and Innovation through Convergence

新戈登研究会议：先进细胞和组织生物制造：通过融合进行技术开发和创新

• 批准号: 10682943
• 负责人: KAIMING YE
• 金额: $ 2.8万
• 依托单位: STATE UNIVERSITY OF NY,BINGHAMTON
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-04-01 至 2024-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10682943
• 关键词: Academia; Acceleration; Address; Attention; Automation; Award; Biological Assay; Biological Process; Biomanufacturing; Bioreactors; Cells; Characteristics; Chemicals; Collaborations; Communities; Complex; Creativeness; Development; Disease; Education; Engineering; Environment; Event; Evolution; Fostering; Generations; Goals; Good Manufacturing Process; Growth; Healthcare; Hour; Industrialization; Industry; Intervention; Learning; Logistics; Manuals; Measurement; Mechanics; Medical; Methods; Modeling; Monitor; Organ; Organoids; Pharmacologic Substance; Postdoctoral Fellow; Prevention; Problem Sets; Procedures; Process; Production; Productivity; Qualifying; Readiness; Regenerative Medicine; Regulation; Relaxation; Reproducibility; Research; Research Personnel; Running; Science; Scientist; Source; Standardization; Students; System; Systems Integration; Technology; Therapeutic; Tissue Engineering; Tissue Model; Tissue Preservation; Tissues; Training; Translations; Underrepresented Populations; Validation; Woman; bench to bedside; biofabrication; career; cohort; data management; design; disease diagnosis; empowerment; experience; fabrication; graduate student; innovation; insight; interest; manufacture; meetings; member; next generation; novel; operation; posters; prevent; research and development; scale up; simulation; skills; symposium; technological innovation; technology development; tool

The recent interest in advanced cell and tissue biomanufacturing offers new opportunities to spur research, education, and industry growth and innovation. Evolution of tissue engineering, regenerative medicine, and additive manufacturing enables the generation of various therapeutic cells and tissues for disease diagnosis, treatment, prevention, and management. Tissue models and organoids have emerged as a way to better understand disease and streamline pharmaceutical development. Despite this progress, the high-level of complexity of the bioproducts relative to other medical products calls for an equivalent high-level convergence and integration—which has yet to emerge—to lead to the production of reliable, scalable, robust, and reproducible constructed tissues on demand. Harnessing these recent advancements, a new Gordon Research Conference entitled “Advanced Cell and Tissue Biomanufacturing: Technology Development and Innovation through Convergence” will identify gaps and challenges that will stimulate new science and technology innovation in advanced biomanufacturing. The conference will highlight the intersection of academic forces with industry niches to accelerate the translation of lab discoveries into industrial scale production of cell and tissue products. Development of enabling technologies and new methods for material and cell sourcing, process modeling and integration, tissue biomanufacturing automation, on- and off-line sensing and control, tissue development and maturation, product validation and functional assays, cell and tissue preservation, regulation, and QA/QC as well as workforce training are essential to foster growth and sustain the field. The meeting will offer a platform for productive interactions across the spectrum or science and engineering from junior investigators and students to leaders in the field. Such interactions will help them to explore new directions of research and build their careers in advanced biomanufacturing. Special attention will be paid to enhancing diversity among investigators and understanding the cultural impacts of these novel interventions.

最近对先进细胞和组织生物制造的兴趣提供了新的机会来刺激 组织工程、再生的研究、教育以及行业发展和创新。 医学和增材制造能够产生各种治疗细胞和组织 疾病诊断、治疗、预防和管理。 成为更好地了解疾病和简化药物开发的一种方式。 这一进展，生物产品相对于其他医疗产品的高度复杂性要求 同等的高水平趋同和一体化（尚未出现）将导致 按需生产可靠、可扩展、坚固且可重复的构建组织。 这些最新进展，一个新的戈登研究会议题为“先进细胞和 组织生物制造：通过融合进行技术开发和创新”将 找出将刺激先进科学技术创新的差距和挑战 会议将强调学术力量与行业利基的交叉。 加速将实验室发现转化为细胞和组织产品的工业规模生产。 开发材料和细胞采购、工艺建模的支持技术和新方法 和集成、组织生物制造自动化、在线和离线传感和控制、组织 开发和成熟、产品验证和功能测定、细胞和组织保存、 监管、质量保证/质量控制以及劳动力培训对于促进该领域的发展和维持至关重要。 该会议将为跨领域或科学和领域的富有成效的互动提供一个平台 从初级研究人员和学生到该领域的领导者，这种互动将对他们有所帮助。 探索新的研究方向并在先进生物制造领域建立自己的职业生涯。 将注意增强调查人员之间的多样性并了解文化影响 这些新颖的干预措施。