Translational Science Training to Reduce the Impact of Alcohol on HIV Infection

减少酒精对艾滋病毒感染影响的转化科学培训

• 批准号: 10223171
• 负责人: Robert L Cook
• 金额: $ 29.35万
• 依托单位: UNIVERSITY OF FLORIDA
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-08-01 至 2023-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10223171
• 关键词: Alcohols; HIV Infections; Training; Translational Research

Creation of a new T32 program in Florida, focused on alcohol and HIV infection, will fulfill a significant need. The state of Florida currently ranks first in new HIV infections per year, second in total HIV/AIDS cases, and third in total US population. Alcohol consumption contributes to poor HIV outcomes and to ongoing HIV transmission, and the relationships between alcohol consumption and HIV can vary by age, gender, ethnicity, and sexual orientation. The University of Florida is an ideal location to host the proposed T32, not only due to its geographic location and access to diverse populations, but also due to our growing NIH-supported alcohol research and infrastructure. The overall objective of this T32 grant is to train and mentor the next generation of researchers who have the skills, knowledge and experience to improve health outcomes in those affected by alcohol and HIV. We need a research task force that is capable of developing and implementing alcohol intervention across diverse populations, who can use novel data systems and sources, and who seek to reduce comorbidities associated with aging. Thus, the specific aims of our training program are to a) deliver an academic curriculum, b) provide outstanding mentoring, c) ensure skills in communication of science, d) provide experience in team science, and e) maximize professionalism and ethical conduct of research. The training program will support up to four pre-doctoral and two post-doctoral trainees at any given time, and several potential candidates have already expressed interest. Trainees will be based in the following academic programs: Epidemiology, Biostatistics, Clinical and Health Psychology, Nursing Science, Health Education and Behavior, and/or the Interdisciplinary Program in Medicine. These programs represent a broad range of health- related disciplines, ensuring trainees will have state of the art training in team science. Our 18 faculty mentors span four colleges and eight departments at UF. Each bring unique skills and expertise related to alcohol and HIV. The training program will ensure appropriate depth in knowledge regarding alcohol, HIV, and three additional focus areas that represent areas of strength in ongoing research at UF: a) health behavior intervention science; b) epidemiology and data science; and c) cognitive science related to aging. The training program will be closely integrated with Southern HIV Alcohol Research Consortium (SHARC), which is supported by over $10 million in ongoing NIAAA funding through 2021. The T32 will be led by three MPIs who each have specific administrative roles, and who will obtain input from an Internal Steering Committee, an Advisory Council, and ongoing program evaluations. UF is an outstanding training environment with many supporting resources, including a pledge to provide an additional $500,000 in overall support to our specific training program. Ultimately, the impact of the training program will be judged by the long-term track record of trainees who complete the training program, which we will monitor over time.

在佛罗里达州创建一个新的 T32 计划，重点关注酒精和艾滋病毒感染，将满足重大需求。 佛罗里达州目前每年新增艾滋病毒感染人数排名第一，艾滋病毒/艾滋病病例总数排名第二， 占美国总人口第三位。饮酒会导致艾滋病毒结果不佳和艾滋病毒持续存在 传播以及饮酒与艾滋病毒之间的关系可能因年龄、性别、种族、 和性取向。佛罗里达大学是举办拟议的 T32 的理想地点，不仅因为 它的地理位置和接触不同人群的机会，而且还得益于我们不断增长的 NIH 支持的酒精饮料 研究和基础设施。 T32 拨款的总体目标是培训和指导下一代 研究人员拥有改善受影响人群健康状况的技能、知识和经验 酒精和艾滋病毒。我们需要一个能够开发和实施酒精的研究工作组 对不同人群进行干预，他们可以使用新颖的数据系统和来源，并且寻求 减少与衰老相关的合并症。因此，我们培训计划的具体目标是 a) 提供 学术课程，b) 提供出色的指导，c) 确保科学传播技能，d) 提供团队科学方面的经验，以及 e) 最大限度地提高研究的专业性和道德行为。这 培训计划将在任何特定时间支持最多四名博士前培训生和两名博士后培训生，并且 一些潜在候选人已经表示了兴趣。学员将在以下学术机构工作 专业：流行病学、生物统计学、临床与健康心理学、护理学、健康教育和 行为学和/或医学跨学科项目。这些计划代表了广泛的健康领域 相关学科，确保学员将接受最先进的团队科学培训。我们的18位导师 横跨佛罗里达大学的四个学院和八个系。每个人都带来与酒精和酒精相关的独特技能和专业知识 艾滋病病毒。培训计划将确保有关酒精、艾滋病毒和三种疾病的知识有适当的深度。 代表佛罗里达大学正在进行的研究优势领域的其他重点领域：a) 健康行为 干预科学； b) 流行病学和数据科学； c) 与衰老相关的认知科学。培训内容 计划将与南方艾滋病毒酒精研究联盟 (SHARC) 紧密结合，该联盟 到 2021 年，将获得超过 1000 万美元的 NIAAA 持续资助。T32 将由三个 MPI 领导，他们 每个人都有特定的管理角色，并且谁将从内部指导委员会、 咨询委员会和正在进行的计划评估。佛罗里达大学是一个优秀的培训环境，拥有许多 支持资源，包括承诺为我们的特定项目提供额外 500,000 美元的总体支持 培训计划。最终，培训计划的影响将通过长期跟踪记录来判断 完成培训计划的学员，我们将对其进行长期监控。