Translational Science Training to Reduce the Impact of Alcohol on HIV Infection

减少酒精对艾滋病毒感染影响的转化科学培训

• 批准号: 10700505
• 负责人: Robert L Cook
• 金额: $ 41.44万
• 依托单位: UNIVERSITY OF FLORIDA
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-08-10 至 2028-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10700505
• 关键词: Alcohols; HIV Infections; Training; Translational Research

This is an application to continue to support both predoctoral trainees and postdoctoral fellows in the T32 training program, “Translational Science Training to Reduce the Impact of Alcohol on HIV Infection”. This training need remains significant across the state of Florida which continues to rank among the top 3 states in new HIV infections per year and total HIV/AIDS cases. Alcohol consumption, and related issues such as drug use and mental health, contributes to enduring HIV transmission and to poor HIV outcomes. We need an interdisciplinary research task force skilled in alcohol research to help reduce HIV transmission and HIV- related comorbidities. The specific aims of our T32 are to: (1) Deliver an outstanding training curriculum focused on alcohol and HIV that incorporates three key focus areas (health behavior intervention science, epidemiology and data science, and cognitive science related to aging); (2) Provide effective mentorship for establishing or advancing programs of research in alcohol and HIV science; (3) Facilitate leaderships skills and experience collaborating with multidisciplinary research teams; (4) Promote excellence in the communication and dissemination of alcohol and HIV science; and (5) Ensure professionalism and ethical conduct of research. The training program will support five pre-doctoral and two post-doctoral trainees at any time and be based in 6 academic programs. The program is led by three MPIs who represent departments of Epidemiology, Health Education and Behavior, and Nursing. We will provide in-depth training around the intersection of alcohol and HIV, together with three additional focus areas: a) health behavior intervention science; b) epidemiology and data science integrated with the UF AI initiative; and c) cognitive science related to aging. Training activities include required courses, T32 Program activities, and training activities associated with the Southern HIV Alcohol Research Consortium (SHARC), itself supported by over $10 million in ongoing NIH funding through 2022. Trainees also will receive training in the responsible conduct of research. The research environment is strong at the University of Florida, which collectively has pledged an additional $500,000 in overall support to our specific training program. Given the success of our trainees to date, and breadth and depth of our faculty mentors’ expertise around alcohol and HIV, we reaffirm our readiness and commitment to training the next cohort of researchers to reduce the risk of negative health outcomes from alcohol and HIV infection throughout Florida and beyond.

这是一份继续支持 T32 博士前培训生和博士后研究员的申请 培训计划，“减少酒精对艾滋病毒感染影响的转化科学培训”。 佛罗里达州的培训需求仍然很大，该州继续位居全美前 3 位。 每年新增的艾滋病毒感染人数和艾滋病毒/艾滋病病例总数，以及相关问题，例如毒品。 的使用和心理健康，会导致艾滋病毒的持久传播和不良的艾滋病毒结果。 跨学科研究工作组擅长酒精研究，以帮助减少艾滋病毒传播和艾滋病毒- 我们的 T32 的具体目标是： (1) 提供出色的培训课程。 重点关注酒精和艾滋病毒，其中包括三个关键重点领域（健康行为干预科学、 (2) 提供有效指导 建立或推进酒精和艾滋病毒科学研究计划；(3) 促进领导技能和 与多学科研究团队合作的经验；（4）促进卓越的沟通； (5) 确保研究的专业性和道德行为。 该培训计划将随时支持5名博士前培训生和2名博士后培训生，并驻扎在6个国家和地区。 该项目由代表流行病学、卫生部门的三个 MPI 领导。 我们将围绕酒精与行为的交叉点提供深入的培训。 艾滋病毒，以及另外三个重点领域：a) 健康行为干预科学；b) 流行病学； 与佛罗里达大学人工智能计划相结合的数据科学；以及 c) 与老龄化相关的认知科学培训活动。 包括与南方艾滋病相关的必修课程、T32 计划活动和培训活动 酒精研究联盟 (SHARC) 本身得到了 NIH 超过 1000 万美元的持续资助， 2022 年。学员还将接受负责任的研究培训。研究环境是。 佛罗里达大学的实力雄厚，该大学集体承诺额外提供 50 万美元的总体支持 鉴于我们的学员迄今为止的成功以及我们教师的广度和深度。 导师在酒精和艾滋病毒方面的专业知识，我们重申我们准备好并致力于培训下一个 一组研究人员致力于降低酒精和艾滋病毒感染对健康造成负面影响的风险 佛罗里达及其他地区。

项目成果

A pseudo-value regression approach for differential network analysis of co-expression data.

用于共表达数据差分网络分析的伪值回归方法。

• 发表时间: 2023-01-09
• 影响因子: 3
• 作者: Ahn, Seungjun;Grimes, Tyler;Datta, Somnath
• 通讯作者: Datta, Somnath

Does Self-Reported or Behavioral Impulsivity Predict Subjective Response to Low-Dose Alcohol?

自我报告或行为冲动是否可以预测对低剂量酒精的主观反应？

• 发表时间: 2019-03-01
• 作者: Berey, Benjamin L;Leeman, Robert F;Pittman, Brian;Franco, Nicholas;Krishnan
• 通讯作者: Krishnan

Practical Considerations in Qualitative Health Research During the COVID-19 Pandemic.

COVID-19 大流行期间定性健康研究的实际考虑。

• 发表时间: 2021
• 作者: Varma, Deepthi S;Young, Mary E;Kreider, Consuelo M;Williams, Katherine;Vaddiparti, Krishna;Parisi, Christina;Semeah, Luz M
• 通讯作者: Semeah, Luz M

(Mis)Perceiving Sexual Intent: A Mixed-Method Approach Investigating Sexual Overperception Across Diverse Sexual Identities.

（错误）感知性意图：调查不同性别身份的性过度感知的混合方法。

• 发表时间: 2024-02
• 影响因子: 3.8
• 作者: Moran, James B;Airington, Zachary;McGee, Emily;Murray, Damian R
• 通讯作者: Murray, Damian R

Using an Electronic Medication Event-Monitoring System for Antiretroviral Therapy Self-Management Among African American Women Living With HIV in Rural Florida: Cohort Study.

使用电子药物事件监测系统对佛罗里达州农村地区感染艾滋病毒的非洲裔美国妇女进行抗逆转录病毒治疗自我管理：队列研究。

• 发表时间: 2020-02-19
• 影响因子: 2.2
• 作者: Lucero, Robert;Williams, Renessa;Esalomi, Tanisia;Alexander;Cook, Christa;Bjarnadottir, Ragnhildur I
• 通讯作者: Bjarnadottir, Ragnhildur I