Web App Technology for Boys and Parents: Improving HPV Vaccine Uptake

面向男孩和家长的网络应用技术：提高 HPV 疫苗的接种率

• 批准号: 9982847
• 负责人: W GILL WOODALL
• 金额: $ 21.57万
• 依托单位: KLEIN BUENDEL, INC.
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-07-18 至 2022-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9982847
• 关键词: 13 year old; Address; Adolescent; Adopted; Adoption; Advisory Committees; Age; Alberta province; Caring; Cellular Phone; Centers for Disease Control and Prevention (U.S.); Childhood; Clinic; Computer software; Computers; Data; Decision Making; Development; Devices; Diffuse; Diffusion of Innovation; Dose; Effectiveness; Ethnic group; Failure; Family; Female; Female Adolescents; Gender; Gills; Goals; Health; Health Communication; Health Sciences; Hispanic Americans; Human Papilloma Virus Vaccination; Human Papilloma Virus Vaccine; Human Papillomavirus; Immunization; Indiana; Intervention; Knowledge; Language; Life; Male Adolescents; Malignant Neoplasms; Malignant Vaginal Neoplasm; Malignant neoplasm of anus; Malignant neoplasm of cervix uteri; Malignant neoplasm of penis; Malignant neoplasm of vulva; Mediating; Mediator of activation protein; Medical; Medical Records; Minority; Native Americans; New Mexico; Outcome; Parents; Pattern; Personal Computers; Population; Preventive healthcare; Principal Investigator; Randomized; Records; Reporting; Research; Research Personnel; Risk; Running; Safety; Schedule; Social Marketing; Sturnus vulgaris; Sum; Surveys; Tablet Computer; Techniques; Technology; Testing; United States; Universities; Update; Vaccination; Vaccines; Woman; Youth; aged; boys; caucasian American; comparison group; comparison intervention; computational platform; design; digital; efficacy trial; follow-up; group intervention; health disparity; improved; innovation; laptop; literacy; male; malignant oropharynx neoplasm; men; mobile application; novel; novel vaccines; pediatric department; programs; recruit; response; uptake; web app

The President's Cancer Advisory Board and the Centers for Disease Control have called for renewed efforts in promoting vaccination for Human Papillomavirus (HPV), including vaccination for adolescent boys, because the uptake of this new vaccine remains alarmingly low. Currently, less than 15% of adolescent boys have received the HPV vaccine; thus, most of this population remains at risk for oropharyngeal, anal, and penile cancers. Many parents remain unconvinced of the safety and effectiveness of HPV vaccines, so effective and accessible messaging to improve decision-making on this vaccine is needed. Parents of adolescent boys also have different concerns about HPV vaccination than for adolescent girls, creating a need for unique health communication interventions to promote vaccine uptake among boys. Interventions also need to address the unique challenges of minority populations and populations for whom English is not the first language. A novel digital intervention will be produced and evaluated for its ability to improve HPV vaccine outcomes. Specifically, a mobile responsive web application (“mobile web app”) will be created that performs similar to a mobile app but runs on a variety of computing platforms from personal desktop and laptop computers to the latest smart phones and tablet computers. Mobile web app content will be targeted to parents and adolescent boys aged 11-13 years living in New Mexico, a majority-minority population with large proportions of Hispanics, Whites, and Native Americans. The specific aims are to: 1) carefully and systematically develop a mobile web app (BoyVac) for smart phones, tablet computers, and personal computers that will utilize Diffusion of Innovations principles to provide targeted information concerning HPV vaccine adoption to adolescent males and their parents, particularly minority adolescents and parents; 2) implement a comprehensive and rigorous test of the impact of the BoyVac mobile web app intervention on HPV vaccine adoption outcomes via a randomized efficacy trial (BoyVac v. usual and customary care); and 3) examine the dose-response relationships between mobile web app usage and vaccine outcomes within a components analysis. A group-randomized pretest-posttest controlled design will be implemented, recruiting 1800 pairs of parents and adolescent boys from 30 pediatric clinics (n=60 parents and boys per clinic) affiliated with the Envision New Mexico, a best practices program at the University of New Mexico Health Sciences Center's Department of Pediatrics. Parents will be surveyed at baseline, a 3-month follow-up, and a 9-month follow-up and records HPV vaccination adoption for the boys will be obtained from the clinics' medical records at the 9- month follow-up. Analyses will test the hypotheses that 1) more 11-13 year old boys in the intervention group (BoyVac mobile web app) will adopt the HPV vaccine than boys in the usual and customary care comparison group and 2) adoption of HPV vaccine will be mediated by improvements in theoretical mediators among parents in the intervention compared to the usual and customary care comparison group.

总统癌症咨询委员会和疾病控制中心呼吁在以下方面继续努力： 促进人乳头瘤病毒 (HPV) 疫苗接种，包括为青春期男孩接种疫苗，因为 目前，只有不到 15% 的青春期男孩接种了这种新疫苗。 接种了 HPV 疫苗；因此，该人群中的大多数仍面临口咽部、肛门和阴茎感染的风险 许多家长仍然不相信 HPV 疫苗的安全性和有效性，以及其有效性和有效性。 还需要提供方便的信息来改善青春期男孩的父母对这种疫苗的决策。 与青春期女孩相比，对 HPV 疫苗接种有不同的担忧，因此需要独特的健康 促进男孩接种疫苗的沟通干预措施还需要解决以下问题。 少数民族人口和英语不是第一语言的人口面临的独特挑战。 将制定数字干预措施并评估其改善 HPV 疫苗效果的能力。 具体来说，将创建一个移动响应式 Web 应用程序（“移动 Web 应用程序”），其执行类似于 移动应用程序，但可以在各种计算平台上运行，从个人台式机和笔记本电脑到 最新的智能手机和平板电脑内容将针对父母和青少年。 居住在新墨西哥州的 11 至 13 岁男孩，该州是少数族裔人口占多数的地区 西班牙裔、白人和美洲原住民的具体目标是： 1) 仔细、系统地开发一个 适用于智能手机、平板电脑和个人电脑的移动网络应用程序 (BoyVac) 创新传播原则，提供有关 HPV 疫苗采用的有针对性的信息 2）实施 全面、严格地测试 BoyVac 移动网络应用干预对 HPV 疫苗的影响 通过随机功效试验（BoyVac 诉常规护理）确定收养结果；3) 检查 组件内移动网络应用程序的使用与疫苗结果之间的剂量反应关系 将实施分组随机前测-后测控制设计，招募 1800 对。 来自 30 个儿科诊所的家长和青春期男孩（每个诊所 60 名家长和男孩） 展望新墨西哥州，新墨西哥大学健康科学中心的最佳实践项目 儿科将在基线、3 个月随访和 9 个月随访时对家长进行调查。 男孩 HPV 疫苗接种情况的记录将从 9-9 点的诊所医疗记录中获取。 一个月的随访分析将检验以下假设：1) 干预组中有更多 11-13 岁男孩。 （BoyVac 移动网络应用程序）在常规和常规护理比较中将比男孩采用 HPV 疫苗 组和 2) HPV 疫苗的采用将通过理论中介因素的改进来调节 干预组中的父母与常规护理对照组进行比较。