Trace Metals Facility Services/Core

痕量金属设施服务/核心

• 批准号: 7406494
• 负责人: Joseph H Graziano
• 金额: $ 21.78万
• 依托单位: COLUMBIA UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-04-01 至 2013-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7406494
• 关键词: Arsenic; Basic Science; Biochemical; Biological; Biological Assay; Biological Markers; Blood; Cadmium; Child; Chromium; Cobalt; Copper; Core Facility; Environmental Pollution; Essential Tremor; Folic Acid; Funding; Generations; Health; Intelligence; Iron; Laboratories; Lead; Lesion; Manganese; Mercury; Metals; Methylation; Physiological; Platinum; Potassium; Purpose; Quality Control; Research Personnel; Risk; Risk Factors; Sampling; Schizophrenia; Score; Selenium; Services; Skin; Sodium; Standardization; Trace metal; Water; Zinc; blood lead; fetal lead exposure; method development; programs

A. Objectives The primary purpose of the Trace Metals Facility Core is to provide CEHNM investigators the ability to obtain analyses of biological samples for a broad array of metals including: lead, mercury, arsenic, iron, manganese, cadmium, copper, zinc, chromium, sodium, cobalt, platinum, potassium and others. In addition, the facility provides method development for these analyses, standardization, and quality control. Biochemical analyses that help in the assessment of the physiological status of the subjects that are exposed to these metals are also conducted. This laboratory is partially funded by our Superfund Basic Research Program (SBRP). In the recent successful competitive renewal of that SBRP, this Facility Core received a priority score of 120.

A. 目标 痕量金属设施核心的主要目的是为 CEHNM 研究人员提供获得 分析生物样品中多种金属，包括：铅、汞、砷、铁、锰、 镉、铜、锌、铬、钠、钴、铂、钾等。此外，该设施 为这些分析、标准化和质量控制提供方法开发。生化分析 有助于评估暴露于这些金属的受试者的生理状态 还进行了。该实验室的部分资金来自我们的超级基金基础研究计划 (SBRP)。在 最近该 SBRP 成功进行了竞争性更新，该设施核心获得了 120 分的优先评分。