Science Education of Alcohol Metabolism

酒精代谢科普教育

基本信息

批准号：
7695054
负责人：
Karen Graf
金额：
$ 51.87万
依托单位：
EDVOTEK, INC.
依托单位国家：
美国
项目类别：
财政年份：
2005
资助国家：
美国
起止时间：
2005-02-01 至 2011-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7695054
关键词：
Acetaldehyde Achievement Adolescence Adolescent Adult Affect Alcohol consumption Alcoholism Alcohols Alleles Award Awareness Bacteria Behavioral Biochemical Biochemistry Biohazardous Substance Biological Biological Assay Biology Biotechnology Cladocera Collaborations Community Health Complement DNA Daphnia Decision Making Development Digestion Drosophila genus Dyes Education Educational Status Educational process of instructing Educational workshop Enzymes Equipment Ethanol Ethanol Metabolism Ethical Issues Ethnic Origin Faculty Family Female Gender Genes Genetic Genetic Polymorphism Genetic Variation Genotype Health Health education Heart Rate Heavy Drinking Human Human Genetics Indiana Individual Invertebrates Investigation Laboratories Learning Left Link Marketing Measurement Measures Metabolic Metabolism Minority Molecular Biology NADH National Institute on Alcohol Abuse and Alcoholism National Research Council Organism Parents Participant Performance Pharmaceutical Preparations Phase Plasmids Population Price Process Public Health Publishing Race Reaction Reagent Reporting Research Resources Restriction fragment length polymorphism Role Sampling School Teachers School-Age Population Schools Science Services Simulate Small Business Innovation Research Grant Societies Students Technology Temperature Testing Time Tobacco Toxic effect Toxin Translating United States United States National Institutes of Health Universities Validation Variant Youth alcohol effect alcohol misuse alcohol related problem base college data sharing design drinking early onset genetic strain hazardous drinking high school male middle school programs psychologic public health relevance research study restriction enzyme science education social symposium teacher underage drinking web site

项目摘要

DESCRIPTION (provided by applicant): Human consumption of alcohol is ubiquitous. While it is reported that ninety percent of the population consumes various amounts of alcohol, only a small but sizable minority of the population abuse alcohol consumption. It is estimated that 10-20% of males and 3-10% of females develop persistent alcohol-related problems. Alcohol use by youth continues to be an important health focus for our Nation. Alcohol misuse among adolescents is on the increase, and excessive drinking is associated with psychological, social and physical harm to the individual, family and society. During the proposed Phase II award period, research will be completed and new experiments and reagents will be tested in workshop and classroom settings prior to the marketing in Phase III. The Company is well established in the science education market and enjoys a fine reputation for its high quality products, technical and education service, and competitive prices. The assessments will be tested and used by workshop participants and classroom students and teachers. Measurement of learning assessments will be based on collaborations with two academic faculty to remove possible bias in these studies. PUBLIC HEALTH RELEVANCE: Alcohol use by youth is an important health focus for our Nation and alcohol misuse among adolescents is on the increase. Excessive drinking is associated with psychological, social and physical harm to the individual, family and society. School age students nationwide report episodes of hazardous drinking of five or more drinks on at least one occasion. Adolescent drinking also leads to poor school performance, criminal involvement and social maladjustments. Equally alarming is evidence that suggests a high correlation between the early-onset of alcohol consumption and the development of alcoholism in adults. The aim of this SBIR is to research and in Phase III to market experiments for grades 7 to 12 on understanding how alcohol is metabolized and that there are differences in the rate of metabolism amongst individuals.

描述（由申请人提供）：人类对酒精的消费无处不在。据报道，有90％的人口消耗了各种饮酒，但只有少数但相当大的人口滥用酒精消费。据估计，男性中有10-20％和3-10％的女性遇到了与酒精有关的问题。青年饮酒仍然是我们国家的重要健康重点。青少年滥用酒精正在增加，过量饮酒与个人，家庭和社会的心理，社会和身体伤害有关。在拟议的第二阶段奖项期间，将完成研究，并在第三阶段的营销之前在研讨会和课堂环境中进行新的实验和试剂。该公司在科学教育市场中建立了良好的建立，并以其高质量的产品，技术和教育服务以及有竞争力的价格享有良好的声誉。研讨会的参与者，课堂学生和老师将测试和使用评估。学习评估的测量将基于与两位学术教师的合作，以消除这些研究中可能的偏见。公共卫生相关性：青年饮酒是我们国家的重要健康重点，青少年的滥用饮酒正在增加。过多的饮酒与个人，家庭和社会的心理，社会和身体伤害有关。全国学生年龄的学生报告至少有一次危险饮酒的剧集。青少年饮酒也导致学校表现不佳，犯罪参与和社交失调。同样令人震惊的证据表明，早期饮酒与成人酒精中毒的发展之间存在很高的相关性。该SBIR的目的是研究和第三阶段，以了解7至12年级的市场实验，了解如何了解酒精的代谢，并且个体中代谢率差异。