CLINICAL CORE

临床核心

• 批准号: 7318790
• 负责人: MARY J KREEK
• 金额: $ 34.38万
• 依托单位: ROCKEFELLER UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-08-01 至 2012-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7318790
• 关键词: Area; Buprenorphine; Clinic; Clinical; Clinical Investigator; Clinical Research; Disease; Drug abuse; Environment; Evaluation; Funding; Genetic; Goals; Health Personnel; Heroin Dependence; Human; Informed Consent; Inpatients; Maintenance; Medical; Medicine; Methadone; Molecular Genetics; Molecular Neurobiology; New York; Numbers; Nurse Practitioners; Nurses; Nursing Research; Outpatients; Pharmacotherapy; Physicians; Professional counselor; Psychologist; Purpose; Research; Research Ethics Committees; Screening procedure; Site; Social Workers; Study Subject; Training; Training and Education; Universities; University Hospitals; follow-up; interest; performance site; programs; response

The Clinical Research Core is a fundamental and essential core of our NIH-NIDA funded Center. The goals of the core are: 1) To provide highly trained staff (physicians, nurse practitioners, nurses, and assistants for research) at all levels to perform the rigorous inpatient molecular neurobiology studies as detailed in Project 4, as well as an outpatient site for performance of related genetic studies, as well as for subject screening, evaluation, and follow-up. 2) The second goal is to develop or maintain strong on-site relationships with a limited number of large, successful programs delivering primarily pharmacotherapy for heroin addiction using methadone maintenance or buprenorphine maintenance for: a. Recruitment of subjects for studies at The Rockefeller University Hospital b. In some cases, conducting onsite human molecular genetics ascertainment studies with local clinic IRBs' Informed Consent, as well as Rockefeller University IRB Informed Consent, both signed c. To identify new problems, including psychiatric and medical problems, new drug abuse problems confronting these groups, as well as any unexpected positive or adverse responses to specific treatments. A broad spectrum of subjects in the greater New York area are used for recruitment. Our related clinic in Las Vegas, NV, is used primarily for identification of problems and confirming or refuting the generalizability of observations made in the greater New York area in another part of our nation. 3) The third goal is to provide a nurturing and rigorous environment for the training of clinical investigators, including physicians, nurse practitioners, research nurses, counselors, psychologists, and a wide variety of healthcare personnel, including social workers and counselors interested in becoming directly involved in addictive diseases research or for the purpose of general education and training in research medicine and/or addictive diseases treatment.

临床研究核心是我们 NIH-NIDA 资助中心的基础和重要核心。目标 的核心是： 1) 提供训练有素的工作人员（医生、执业护士、护士和研究助理） 执行项目 4 中详述的严格的住院患者分子神经生物学研究的水平，以及 用于进行相关遗传学研究以及受试者筛选、评估和治疗的门诊场所 后续行动。 2) 第二个目标是与有限数量的大型、 成功的项目主要是使用美沙酮维持治疗海洛因成瘾提供药物治疗 或丁丙诺啡维持治疗： 一个。洛克菲勒大学医院招募研究对象 b.在某些情况下，与当地诊所 IRB 一起进行现场人类分子遗传学确定研究 知情同意书以及洛克菲勒大学 IRB 知情同意书均已签署 c.发现新问题，包括精神和医疗问题、新的药物滥用问题 面对这些群体，以及对特定治疗的任何意外的积极或不利反应。一个 大纽约地区的广泛科目用于招聘。我们位于 拉斯 的相关诊所 内华达州维加斯主要用于识别问题并确认或反驳以下问题的普遍性 在我国另一地区的大纽约地区进行的观察。 3）第三个目标是为临床研究者的培训提供培育和严格的环境， 包括医生、执业护士、研究护士、咨询师、心理学家以及各种各样的人 医护人员，包括有兴趣直接参与的社会工作者和辅导员 成瘾疾病研究或用于研究医学的普通教育和培训和/或 成瘾性疾病的治疗。