针对患有阿片类药物使用障碍和严重精神疾病的初级保健患者调整和实施慢性病自我管理计划-猫眼课题宝

批准号：
10785110
负责人：
Elizabeth Siantz
金额：
$ 18.66万
依托单位：
UNIVERSITY OF UTAH
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-09-30 至 2028-08-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10785110
关键词：
Address Adoption Adult Area Behavior Buprenorphine Caring Chronic Disease Clinic Clinical Clinical Investigator Clinical Trials Clinical Trials Design Communities Complex Disease Disease Management Dissemination and Implementation Doctor of Philosophy Education Educational Intervention Environment Ethnography Evidence based treatment Feasibility Studies Formulation Foundations Future Goals Health Health education Helping to End Addiction Long-term Hybrids Improve Access Intervention Interview Leadership Mental Health Associations Mental Health Services Mentored Research Scientist Development Award Mentors Methods Naltrexone Outcome Participant Patient Education Patients Persons Pharmaceutical Preparations Pilot Projects Population Positioning Attribute Primary Care Procedures Process Provider Qualitative Evaluations Quality of Care Randomized Reporting Research Research Personnel Resources Science Scientist Self Management Services Site Social Workers Statistical Data Interpretation Symptoms Testing Time Training Training Activity United States National Institutes of Health acceptability and feasibility addiction career career development contextual factors design education resources effectiveness study ethnographic method evidence base experience feasibility testing gaps in access gender diversity gender equity health related quality of life high risk implementation barriers implementation context implementation evaluation implementation facilitators implementation intervention implementation process implementation research implementation science improved innovation medication for opioid use disorder mortality novel opioid epidemic opioid overdose opioid use disorder patient population peer physical conditioning primary care clinic primary care patient primary care provider primary care services primary care setting programs randomized trial satisfaction self-management program severe mental illness skill acquisition skills social health determinants social vulnerability systematic review tool treatment as usual

Address Adoption Adult Area Behavior Buprenorphine Caring Chronic Disease Clinic Clinical Clinical Investigator Clinical Trials Clinical Trials Design Communities Complex Disease Disease Management Dissemination and Implementation Doctor of Philosophy Education Educational Intervention Environment Ethnography Evidence based treatment Feasibility Studies Formulation Foundations Future Goals Health Health education Helping to End Addiction Long-term Hybrids Improve Access Intervention Interview Leadership Mental Health Associations Mental Health Services Mentored Research Scientist Development Award Mentors Methods Naltrexone Outcome Participant Patient Education Patients Persons Pharmaceutical Preparations Pilot Projects Population Positioning Attribute Primary Care Procedures Process Provider Qualitative Evaluations Quality of Care Randomized Reporting Research Research Personnel Resources Science Scientist Self Management Services Site Social Workers Statistical Data Interpretation Symptoms Testing Time Training Training Activity United States National Institutes of Health acceptability and feasibility addiction career career development contextual factors design education resources effectiveness study ethnographic method evidence base experience feasibility testing gaps in access gender diversity gender equity health related quality of life high risk implementation barriers implementation context implementation evaluation implementation facilitators implementation intervention implementation process implementation research implementation science improved innovation medication for opioid use disorder mortality novel opioid epidemic opioid overdose opioid use disorder patient population peer physical conditioning primary care clinic primary care patient primary care provider primary care services primary care setting programs randomized trial satisfaction self-management program severe mental illness skill acquisition skills social health determinants social vulnerability systematic review tool treatment as usual

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This K01 award application is for Dr. Elizabeth Siantz, a PhD-trained social worker whose overarching career goal is to become an independent clinical investigator who uses implementation science to promote the adoption and integration of evidence-based Chronic Disease Self-Management programs for persons with chronic disease, primarily opioid use disorder (OUD) and serious mental illness (SMI). This K01 will support four key areas of career development: 1) intervention adaptation as it relates to the mental health and primary care needs of persons with OUD; 2) training in clinical trial design and management in real-world settings; 3) advanced skills for qualitatively evaluating intervention implementation; and 4) strengthening research leadership with a focus on gender equity and diversity in science. Dr. Siantz has assembled an interdisciplinary mentoring team comprised of Adam Gordon, MD (Primary Mentor), who is an expert dissemination and implementation (D&I) researcher focused on improving quality of care to vulnerable patient populations with OUD; and Leopoldo Cabassa, PhD, MSW (co-mentor), an expert mixed-methods D&I researcher focused on promoting the physical health of persons with SMI. Additional advisors include: Gerald Cochran, PhD, MSW, a clinical trialist with OUD expertise; Lawrence Palinkas, PhD, an expert in mixed-method designs for D&I research; Angela Presson, PhD, an expert in clinical trials statistical analyses; and Angela Fagerlin, PhD, an expert in patient decision support interventions and in gender equity and diversity in research leadership. People with OUD have a high co-occurrence of serious mental illness (SMI) and other chronic diseases, and are often challenged by their clinical symptoms and social vulnerabilities. While primary care settings frequently treat patients with OUD and SMI, primary care providers have few tools to support this population in self-managing these complex health conditions. Chronic Disease Self-Management programs (CDSMPs) can improve disease management skills and behaviors, but have not been adapted for primary care patients with OUD and SMI. Un-adapted versions might lack relevance to this population and setting. Dr. Siantz will address this implementation gap. This research will support a future hybrid-effectiveness study to test the adapted CDSMP for primary care patients with OUD and SMI. This study’s Specific Aims include: 1) Adapt the CDSMP for adults with OUD and SMI for implementation in a primary care setting using the Collaborative Intervention Planning Framework; 2) Test the feasibility, acceptability, and initial impact of the adapted CDSMP for persons with SMI and OUD in a primary care setting; and 3) Evaluate implementation process and context of the adapted CDSMP using Rapid Assessment Method Informed Clinical Ethnography. This proposed research is significant because it will develop a health education resource for a population at high risk for early mortality. The proposed research is innovative because it will extend an existing CDSMP to a new patient population (persons with OUD and SMI) and novel setting (primary care).

该K01奖项申请是针对受过博士培训的社会工作者伊丽莎白·塞安茨（Elizabeth Siantz）博士的职业目标是成为一个独立的临床研究者，他使用实施科学来促进为患有循证的慢性疾病自我管理计划采用和整合慢性疾病，原发性阿片类药物使用障碍（OUD）和严重的精神疾病（SMI）。这个K01将支持职业发展的四个关键领域：1）与心理健康有关的干预适应 Oud的人的关心需求； 2）在现实世界中的临床试验设计和管理培训； 3）定性评估干预实施的高级技能； 4）加强研究领导着专注于科学方面的性别平等和多样性。 Siantz博士汇集了一个跨学科指导团队完成了医学博士亚当·戈登（Adam Gordon）（主要导师），他是专家传播和实施（D＆I）研究人员致力于提高对弱势患者人群的护理质量 Oud;以及MSW的Leopoldo Cabassa博士（Co-Incertor），专家混合方法D＆I研究人员专注于促进SMI患者的身体健康。其他顾问包括：Gerald Cochran，博士，MSW，A OUD专业知识的临床试验员； Lawrence Palinkas博士，D＆I混合方法设计专家研究; Angela Presson博士，临床试验统计分析的专家；和安吉拉·法格林（Angela Fagerlin）博士患者决策的实验支持干预措施以及研究领导中的性别平等和多样性。 OUD患者具有很高的严重精神疾病（SMI）和其他慢性病疾病，通常受到其临床症状和社会脆弱性的挑战。而初级保健设置经常用OUD和SMI治疗患者，初级保健提供者几乎没有工具来支持这一点自我管理这些复杂健康状况的人口。慢性疾病自我管理计划（CDSMP）可以提高疾病管理技能和行为，但尚未适应初级保健 OUD和SMI的患者。未适应的版本可能与该人群和设置缺乏相关性。博士 Siantz将解决此实施差距。这项研究将支持未来的混合效应研究测试适用于OUD和SMI的初级保健患者的CDSMP。这项研究的具体目的包括：1）使用OUD和SMI的成年人调整CDSMP，以便在初级保健设置中使用协作干预计划框架； 2）测试可行性，可接受性和最初影响在初级保健环境中为患有SMI和OUD的人改编了CDSMP； 3）评估实施使用快速评估方法知情临床人种志的改编CDSMP的过程和背景。这项拟议的研究很重要，因为它将为人群开发健康教育资源早期死亡率的高风险。拟议的研究具有创新性，因为它将将现有的CDSMP扩展到新的患者人群（具有OUD和SMI的人）和新颖的环境（初级保健）。

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数据更新时间：2024-06-01

Adapting and Implementing a Chronic Disease Self-Management Program for Primary Care Patients with Opioid Use Disorder and Serious Mental Illness

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