Recharge Behavioral Therapy for caregivers of individuals with Alzheimer's Disease

为阿尔茨海默病患者的护理人员提供充电行为疗法

• 批准号: 10761621
• 负责人: BRUNO KAJIYAMA
• 金额: $ 49.34万
• 依托单位: PHOTOZIG, INC.
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-05 至 2024-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10761621
• 关键词: Address; Alzheimer' s Disease; Alzheimer' s disease care; Alzheimer' s disease caregiver; Alzheimer' s disease patient; American; Anxiety; Apple; Behavior; Behavior Therapy; Behavioral; Calendar; Caregivers; Caring; Charge; Clinical Trials; Cognitive; Complement; Coping Skills; Creativeness; Data; Dementia; Dementia caregivers; Development; Distress; Educational Curriculum; Educational process of instructing; Effectiveness; Effectiveness of Interventions; Emotional; Emotions; Environment; Evaluation; Event; Family; Family Caregiver; Family member; Fees; Focus Groups; Fostering; Goals; Health; Home; Hybrids; Incidence; Individual; Institutionalization; Intervention; Learning; Link; Literature; Location; Marketing; Mental Depression; Methods; Moods; Music; Notification; Outcome; Patients; Personal Satisfaction; Personality; Persons; Pharmaceutical Preparations; Phase; Play; Protocols documentation; Publishing; Quality of life; Randomized; Reporting; Research; Rewards; Role; Services; Stress; Symptoms; Testing; Therapeutic Intervention; Time; Training; Training Programs; Translating; Well in self; care burden; care systems; caregiver stress; caregiving; chronic pain; coping; cost; cost effective intervention; dementia caregiving; depressive symptoms; design; economic cost; effective therapy; evidence base; feasibility testing; flexibility; high risk; improved; informal care; innovation; mindfulness; mindfulness intervention; mobile application; online care; prevent; programs; prototype; psychoeducation; psychoeducational; public health relevance; randomized, clinical trials; recruit; recurrent depression; relapse prevention; skills; social; stress management; stress reduction; stress symptom; usability

Project Summary Caring for individuals with Alzheimer's Disease (AD) is associated with depressive symptoms and “burden” because dealing with AD patient's cognitive, behavioral and personality changes is very challenging and stressful for caregivers. There are over 11 million AD caregivers in the US, providing informal care services to family members, with high incidences of stress (59%) and depressive symptoms (30%). Clinical trials and other academic research demonstrated the benefits of non-pharmacological interventions to improve the psychological well-being of AD caregivers, however there is a recognized need to translate these programs to accessible products/services and deliver them widely at minimum cost. To address these needs, we propose the new Recharge Behavioral Therapy (RBT), derived from an evidence- based protocol to treat depression (Behavioral Activation) and a proven program to train coping skills (Coping With Caregiving). We will translate prior research, combine powerful behavioral activation methods, and tailor the integrated curriculum for AD caregivers into a new intervention to reduce stress and depressive symptoms. Besides being an effective treatment for depression (efficacy stablished by multiple clinical trials), Behavioral Activation (BA) was selected because it motivates individuals to engage in healthy behaviors to improve their wellness. AD caregivers usually sacrifice their own physical and emotional needs, when providing care. The BA component will encourage caregivers to take care of their own well-being and “Recharge their energy” in their caregiving journey, so that they can fulfil their caregiver role at their best and improve their quality of life. Coping With Caregiving (CWC) is a psychoeducational training program for AD caregivers, evaluated in several clinical trials with demonstrated effectiveness in decreasing caregiver distress, burden of care, stress, and depression. By integrating CWC in RBT, we will provide the necessary consideration to the AD caregiving context and the resulting intervention will contain beneficial coping strategies for AD caregivers. Furthermore, the implementation mechanism for the RBT intervention will be the new Recharge Mobile App (RMA), an interactive, easy to use, and engaging mobile app that can be deployed to millions of people on demand (app install from app stores) and at very low cost (small subscription fee). RMA will be tailored for AD caregivers with training, practices, and content for RBT, which is not available in the market. Creative use of app features (interactivity, compliance, and notifications) will engage caregivers. Phase I will determine the initial RBT curriculum, develop the RMA prototype, and evaluate the feasibility. Phase II will fully develop RBT/RMA and evaluate the intervention effectiveness with a randomized clinical trial. RMA will help to reduce caregiver stress and depressive symptoms related to AD caregiving with a non- pharmacological approach; offering an effective, low-cost, and accessible mobile app to be disseminated to innumerous families struggling with Alzheimer's Disease through Apple and Google Play app stores.

项目摘要 照顾阿尔茨海默氏病（AD）的人与抑郁症状和“负担”有关 因为处理广告患者的认知，行为和个性变化是非常挑战的，并且 压力很大。美国有超过1100万的广告护理人员，提供非正式护理服务 家庭成员，有高压力（59％）和抑郁症状（30％）。 临床试验和其他学术研究表明，非药理干预的好处 改善广告护理人员的心理健康，但是有必要将其翻译 计划以最低成本访问产品/服务并广泛交付它们。 为了满足这些需求，我们提出了源自证据的新补给行为疗法（RBT） 基于治疗抑郁症（行为激活）和培训应对技巧的验证计划（应对 带有照料）。我们将翻译先前的研究，结合强大的行为激活方法和量身定制 广告护理人员的综合课程进行新的干预措施，以减轻压力和抑郁症状。 除了是抑郁症的有效治疗方法（通过多个临床试验施加功效），行为 之所以选择激活（BA），是因为它促使个人参与健康的行为以改善自己的行为 健康。广告护理人员通常在提供护理时牺牲自己的身体和情感需求。这 BA组件将鼓励看护人照顾自己的福祉，并在 他们的护理旅程，以便他们可以在最佳状态履行照顾者角色并提高生活质量。 应对护理（CWC）是针对广告护理人员的心理教育培训计划，并评估 几项临床试验表明，在减少护理人员的痛苦，护理，压力，压力， 和抑郁。通过将CWC集成到RBT中，我们将为广告护理提供必要的考虑 上下文和由此产生的干预措施将包含广告护理人员的有益应对策略。 此外，RBT干预的实施机制将是新的充电移动应用 （RMA），一种交互式，易于使用和引人入胜的移动应用程序，可以部署给数百万的人 需求（来自应用商店的应用程序安装）和成本非常低（小订阅费）。 RMA将针对RBT的培训，实践和内容量身定制的广告护理人员，这在 市场。对应用程序功能（交互，合规性和通知）的创造性使用将吸引护理人员。 第一阶段将确定初始RBT课程，开发RMA原型并评估可行性。 第二阶段将通过一项随机临床试验完全发展RBT/RMA并评估干预效果。 RMA将有助于减轻与非 - 药理方法；提供有效的，低成本且可访问的移动应用程序，以传播到 通过Apple和Google Play应用商店挣扎的无数家庭与阿尔茨海默氏病斗争。