Mindfulness-based Cognitive Coping Mobile App Intervention for caregivers of individuals with Alzheimer's Disease

针对阿尔茨海默病患者护理人员的基于正念的认知应对移动应用程序干预

• 批准号: 10322963
• 负责人: BRUNO KAJIYAMA
• 金额: $ 98.1万
• 依托单位: PHOTOZIG, INC.
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-09-15 至 2023-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10322963
• 关键词: Address; Adoption; Adult; Affect; Age; Age-Years; Alzheimer' s Disease; Alzheimer' s disease care; Alzheimer' s disease caregiver; Alzheimer' s disease patient; American; Android; Awareness; Caregiver Burden; Caregivers; Caring; Cellular Phone; Centers for Disease Control and Prevention (U.S.); Clinical Trials; Cognitive; Communities; Coping Skills; Data; Dementia; Dementia caregivers; Depressed mood; Deterioration; Distress; Educational Curriculum; Effectiveness; Emergency department visit; Evaluation; Exercise; Family; Family Caregiver; Feeling; Focus Groups; Fostering; Funding Opportunities; Goals; Government; Health; Home; Hospitalization; Human Resources; Individual; Informal Social Control; Institutionalization; Intervention; Knowledge; Lead; Learning; Left; Major Depressive Disorder; Mental Depression; Mind; Modeling; Monitor; Motivation; Neurons; Notification; Outcome; Ownership; Patients; Pattern; Pharmaceutical Preparations; Phase; Process; Prophylactic treatment; Psychological Stress; Publishing; Quality of life; Randomized; Randomized Clinical Trials; Recurrence; Relapse; Reporting; Research; Resources; Rest; Role; Services; Severities; Shoulder; Side; Societies; Stress; Symptoms; Techniques; Thinking; Time; Training; Translating; United States National Institutes of Health; Update; Well in self; Work; base; cardiovascular disorder risk; care giving burden; care outcomes; caregiver education; caregiver interventions; caregiving; coping; cost; cost effective intervention; crowdsourcing; dementia caregiving; depressive symptoms; experience; improved; informal caregiver; innovation; insight; mindfulness; mindfulness based cognitive therapy; mobile application; novel; phase 1 study; physical conditioning; prevent; programs; prototype; psychologic; public health relevance; recruit; recurrent depression; response; rural underserved; skills training; smartphone Application; societal costs; stress symptom; tool; usability; web site

Project Summary Alzheimer's Disease (AD) is a devastating illness for patients, families, and society. Most of the care of AD patients rests on shoulders of informal caregivers, largely untrained to undertake the caregiving role, bearing a high level of distress, and suffering deterioration in physical health and psychological well-being. There are over 16 million Americans providing care to AD patients, experiencing high rates of depressive symptoms (30%), stress (59%), associated risks for cardiovascular diseases, and many other adverse health effects. For example, in separate studies, hospitalization and emergency department visits were more likely for dementia caregivers than any other types of caregivers. The severity of AD caregiving is influenced by several factors, such as intensity of dementia symptoms in AD patients, how challenging distressful situations are perceived by caregivers, and available resources. Although information and programs about Alzheimer's Disease are available to the public, an essential missing tool is how to deal with depressive symptoms in an effective manner, as they are very common and demanding. Therefore, in this Phase II project, we propose to complete the new Mindfulness-based Cognitive Coping (MCC) intervention, and enable easy access with our mobile app, called Caring Mind App (CMA), providing an effective cost-effective intervention for caregivers to reduce their stress and depressive symptoms. The MCC intervention is built upon the Mindfulness-Based Cognitive Therapy (MBCT), which has been effective to treat individuals with major depressive disorder, with the integration of caregiving coping strategies from our past studies to help caregivers to overcome stressful situations in their caregiver role. Innovation: (1) integration of MBCT with caregiving coping in a mobile app; (2) anonymous sharing of real responses and techniques used by caregivers; and (3) automated content update through an advanced “crowdsourcing” of caregiving knowledge (after “curation” by project personnel) to promote best practices. Phase I demonstrated the feasibility, met all milestones, and provided evidence to support the concept (MCC in app format). AD caregivers were able to use the Caring Mind mobile App and accepted it very well. In fact, besides demonstrating usability, acceptance and perceived benefits, Phase I study showed significant positive outcomes for caregivers on reducing their depressive symptoms and psychological stress. In Phase II, we will finalize the MCC curriculum, develop the complete app, and evaluate its effectiveness in a randomized clinical trial; resulting in a novel intervention that integrates MCC content, aggregation of community shared experience, effective training to reduce depressive symptoms and psychological stress, and a mobile app to be deployed to millions of families struggling with Alzheimer's Disease. Commercial Opportunity: MCC program will be available to AD caregivers (16+ Million people in US) as a mobile app subscription. This model has been very successful with our current mobile apps in App Stores.

项目摘要 阿尔茨海默氏病（AD）是患者，家庭和社会的毁灭性疾病。广告的大部分护理 患者靠在非正式护理人员的肩膀上，在很大程度上没有受过训练来担任护理角色， 高水平的困扰，身体健康和心理健康的恶化。 有超过1600万的美国人为广告患者提供护理，经历了高抑郁症的速度 症状（30％），压力（59％），心血管疾病的相关风险以及许多其他不良健康 效果。例如，在单独的研究中，住院和急诊就诊更有可能 痴呆症护理人员比任何其他类型的护理人员。 AD护理的严重程度受到多种因素的影响，例如AD中的痴呆症症状强度 患者，护理人员如何看待挑战障碍的情况以及可用的资源。虽然 有关阿尔茨海默氏病的信息和计划可供公众使用，必不可少的工具是 如何以有效的方式应对抑郁症状，因为它们非常普遍且苛刻。 因此，在此II阶段项目中，我们建议完成新的基于正念的认知应对 （MCC）干预，并可以轻松使用我们的移动应用程序，称为Caring Mind App（CMA），提供了 有效的具有成本效益的干预措施，以减轻压力和抑郁症状。 MCC干预措施建立在基于正念的认知疗法（MBCT）的基础上，该疗法一直是 有效治疗患有重度抑郁症的人，并结合护理应对策略 从过去的研究中，可以帮助护理人员克服压力大小的护理人员角色。 创新：（1）MBCT与移动应用程序中的护理应对集成； （2）真实的匿名共享 护理人员使用的反应和技术； （3）通过高级的自动化内容更新 护理知识（项目人员的“策划”之后）“众包”以促进最佳实践。 第一阶段证明了可行性，达到了所有里程碑，并提供了支持该概念的证据（MCC 以应用程序格式）。广告护理人员能够使用Caring Mind Mobile应用程序，并很好地接受了它。实际上， 除了证明可用性，接受和感知的益处外，第一阶段研究表明了显着的积极 护理人员减轻抑郁症状和心理压力的结果。 在第二阶段，我们将最终确定MCC课程，开发完整的应用程序，并评估其在A中的有效性 随机临床试验；导致了整合MCC含量的新颖干预措施 社区共同的经验，有效的培训以减轻抑郁症状和心理压力，以及 一个移动应用程序，该应用程序将部署到数百万的家庭中，他们陷入了阿尔茨海默氏病。 商业机会：MCC计划将向广告护理人员（美国16多人）作为一个 移动应用订阅。我们当前在应用商店中的移动应用程序非常成功。