Mindfulness-based Cognitive Coping Mobile App Intervention for caregivers of individuals with Alzheimer's Disease

针对阿尔茨海默病患者护理人员的基于正念的认知应对移动应用程序干预

• 批准号: 10468322
• 负责人: BRUNO KAJIYAMA
• 金额: $ 98.93万
• 依托单位: PHOTOZIG, INC.
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-09-15 至 2024-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10468322
• 关键词: Address; Adoption; Adult; Affect; Age; Age-Years; Alzheimer' s Disease; Alzheimer' s disease care; Alzheimer' s disease caregiver; Alzheimer' s disease patient; American; Android; Awareness; Caregivers; Caring; Cellular Phone; Centers for Disease Control and Prevention (U.S.); Clinical Trials; Cognitive; Communities; Coping Skills; Data; Dementia; Dementia caregivers; Depressed mood; Deterioration; Distress; Educational Curriculum; Effectiveness; Emergency department visit; Evaluation; Exercise; Family; Family Caregiver; Feeling; Focus Groups; Fostering; Funding Opportunities; Goals; Government; Health; Home; Hospitalization; Human Resources; Individual; Informal Social Control; Institutionalization; Intervention; Knowledge; Lead; Learning; Left; Major Depressive Disorder; Mental Depression; Mind; Modeling; Monitor; Motivation; Neurons; Notification; Outcome; Ownership; Patients; Pattern; Persons; Pharmaceutical Preparations; Phase; Process; Prophylactic treatment; Psychological Stress; Publishing; Quality of life; Randomized; Randomized Clinical Trials; Recurrence; Relapse; Reporting; Research; Resources; Rest; Role; Services; Severities; Shoulder; Side; Societies; Stress; Symptoms; Techniques; Thinking; Time; Training; Translating; United States National Institutes of Health; Update; Well in self; Work; base; cardiovascular disorder risk; care giving burden; care outcomes; caregiver education; caregiver interventions; caregiver stress; caregiving; coping; cost; cost effective intervention; crowdsourcing; dementia caregiving; depressive symptoms; experience; improved; informal caregiver; innovation; insight; mindfulness; mindfulness based cognitive therapy; mobile application; novel; phase 1 study; physical conditioning; prevent; programs; prototype; psychologic; public health relevance; recruit; recurrent depression; response; rumination; rural underserved; skills training; smartphone Application; societal costs; stress symptom; tool; usability; web site

Project Summary Alzheimer's Disease (AD) is a devastating illness for patients, families, and society. Most of the care of AD patients rests on shoulders of informal caregivers, largely untrained to undertake the caregiving role, bearing a high level of distress, and suffering deterioration in physical health and psychological well-being. There are over 16 million Americans providing care to AD patients, experiencing high rates of depressive symptoms (30%), stress (59%), associated risks for cardiovascular diseases, and many other adverse health effects. For example, in separate studies, hospitalization and emergency department visits were more likely for dementia caregivers than any other types of caregivers. The severity of AD caregiving is influenced by several factors, such as intensity of dementia symptoms in AD patients, how challenging distressful situations are perceived by caregivers, and available resources. Although information and programs about Alzheimer's Disease are available to the public, an essential missing tool is how to deal with depressive symptoms in an effective manner, as they are very common and demanding. Therefore, in this Phase II project, we propose to complete the new Mindfulness-based Cognitive Coping (MCC) intervention, and enable easy access with our mobile app, called Caring Mind App (CMA), providing an effective cost-effective intervention for caregivers to reduce their stress and depressive symptoms. The MCC intervention is built upon the Mindfulness-Based Cognitive Therapy (MBCT), which has been effective to treat individuals with major depressive disorder, with the integration of caregiving coping strategies from our past studies to help caregivers to overcome stressful situations in their caregiver role. Innovation: (1) integration of MBCT with caregiving coping in a mobile app; (2) anonymous sharing of real responses and techniques used by caregivers; and (3) automated content update through an advanced “crowdsourcing” of caregiving knowledge (after “curation” by project personnel) to promote best practices. Phase I demonstrated the feasibility, met all milestones, and provided evidence to support the concept (MCC in app format). AD caregivers were able to use the Caring Mind mobile App and accepted it very well. In fact, besides demonstrating usability, acceptance and perceived benefits, Phase I study showed significant positive outcomes for caregivers on reducing their depressive symptoms and psychological stress. In Phase II, we will finalize the MCC curriculum, develop the complete app, and evaluate its effectiveness in a randomized clinical trial; resulting in a novel intervention that integrates MCC content, aggregation of community shared experience, effective training to reduce depressive symptoms and psychological stress, and a mobile app to be deployed to millions of families struggling with Alzheimer's Disease. Commercial Opportunity: MCC program will be available to AD caregivers (16+ Million people in US) as a mobile app subscription. This model has been very successful with our current mobile apps in App Stores.

项目概要 阿尔茨海默病（AD）是一种对患者、家庭和社会来说都是毁灭性的疾病。 病人靠在非正式护理人员的肩膀上，这些护理人员基本上没有接受过承担护理角色的培训，承担着 高度痛苦，身体健康和心理健康恶化。 有超过 1600 万美国人为 AD 患者提供护理，他们的抑郁症发病率很高 症状（30%）、压力（59%）、心血管疾病的相关风险以及许多其他不良健康 例如，在单独的研究中，住院和急诊就诊的可能性更大。 痴呆症护理人员比任何其他类型的护理人员都要多。 AD 护理的严重程度受多种因素影响，例如 AD 痴呆症状的强度 患者、护理人员如何看待具有挑战性的痛苦情况以及可用的资源。 尽管有关阿尔茨海默病的信息和计划已向公众开放，但缺少一个重要的工具是 如何有效地应对抑郁症状，因为它们非常常见且要求很高。 因此，在这个二期项目中，我们建议完成新的基于正念的认知应对 (MCC) 干预，并通过我们的移动应用程序（称为 Caring Mind App (CMA)）轻松访问，提供 为护理人员提供有效且具有成本效益的干预措施，以减轻他们的压力和抑郁症状。 MCC 干预建立在基于正念的认知疗法 (MBCT) 的基础上，该疗法已被 结合护理应对策略，可有效治疗重度抑郁症患者 根据我们过去的研究，帮助护理人员克服护理角色中的压力情况。 创新：(1) 将 MBCT 与护理应对整合在移动应用程序中；(2) 匿名分享真实信息； 护理人员使用的反应和技术；(3) 通过先进的自动内容更新 “众包”护理知识（由项目人员“策划”后）以推广最佳实践。 第一阶段展示了可行性，达到了所有里程碑，并提供了支持该概念的证据（MCC AD 护理人员能够使用 Caring Mind 移动应用程序，并且接受得很好。 除了展示可用性、接受度和感知效益之外，第一阶段研究还显示出显着的积极作用 护理人员减少抑郁症状和心理压力的结果。 在第二阶段，我们将最终确定 MCC 课程，开发完整的应用程序，并评估其有效性 随机临床试验；产生整合 MCC 内容、汇总的新型干预措施 社区分享经验、有效培训以减轻抑郁症状和心理压力，以及 一款将部署到数百万患有阿尔茨海默病的家庭的移动应用程序。 商业机会：MCC 计划将作为 AD 护理人员（美国超过 1600 万人）提供 移动应用程序订阅模式对于我们当前在应用程序商店中的移动应用程序来说非常成功。