New GORDON RESEARCH CONFERENCE: Advanced Cell and Tissue Biomanufacturing: Technology Development and Innovation through Convergence

新戈登研究会议：先进细胞和组织生物制造：通过融合进行技术开发和创新

• 批准号: 10682943
• 负责人: KAIMING YE
• 金额: $ 2.8万
• 依托单位: STATE UNIVERSITY OF NY,BINGHAMTON
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-04-01 至 2024-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10682943
• 关键词: Academia; Acceleration; Address; Attention; Automation; Award; Biological Assay; Biological Process; Biomanufacturing; Bioreactors; Cells; Characteristics; Chemicals; Collaborations; Communities; Complex; Creativeness; Development; Disease; Education; Engineering; Environment; Event; Evolution; Fostering; Generations; Goals; Good Manufacturing Process; Growth; Healthcare; Hour; Industrialization; Industry; Intervention; Learning; Logistics; Manuals; Measurement; Mechanics; Medical; Methods; Modeling; Monitor; Organ; Organoids; Pharmacologic Substance; Postdoctoral Fellow; Prevention; Problem Sets; Procedures; Process; Production; Productivity; Qualifying; Readiness; Regenerative Medicine; Regulation; Relaxation; Reproducibility; Research; Research Personnel; Running; Science; Scientist; Source; Standardization; Students; System; Systems Integration; Technology; Therapeutic; Tissue Engineering; Tissue Model; Tissue Preservation; Tissues; Training; Translations; Underrepresented Populations; Validation; Woman; bench to bedside; biofabrication; career; cohort; data management; design; disease diagnosis; empowerment; experience; fabrication; graduate student; innovation; insight; interest; manufacture; meetings; member; next generation; novel; operation; posters; prevent; research and development; scale up; simulation; skills; symposium; technological innovation; technology development; tool

The recent interest in advanced cell and tissue biomanufacturing offers new opportunities to spur research, education, and industry growth and innovation. Evolution of tissue engineering, regenerative medicine, and additive manufacturing enables the generation of various therapeutic cells and tissues for disease diagnosis, treatment, prevention, and management. Tissue models and organoids have emerged as a way to better understand disease and streamline pharmaceutical development. Despite this progress, the high-level of complexity of the bioproducts relative to other medical products calls for an equivalent high-level convergence and integration—which has yet to emerge—to lead to the production of reliable, scalable, robust, and reproducible constructed tissues on demand. Harnessing these recent advancements, a new Gordon Research Conference entitled “Advanced Cell and Tissue Biomanufacturing: Technology Development and Innovation through Convergence” will identify gaps and challenges that will stimulate new science and technology innovation in advanced biomanufacturing. The conference will highlight the intersection of academic forces with industry niches to accelerate the translation of lab discoveries into industrial scale production of cell and tissue products. Development of enabling technologies and new methods for material and cell sourcing, process modeling and integration, tissue biomanufacturing automation, on- and off-line sensing and control, tissue development and maturation, product validation and functional assays, cell and tissue preservation, regulation, and QA/QC as well as workforce training are essential to foster growth and sustain the field. The meeting will offer a platform for productive interactions across the spectrum or science and engineering from junior investigators and students to leaders in the field. Such interactions will help them to explore new directions of research and build their careers in advanced biomanufacturing. Special attention will be paid to enhancing diversity among investigators and understanding the cultural impacts of these novel interventions.

最近对高级细胞和组织生物制造的兴趣为刺激的新机会 研究，教育以及行业的增长与创新。组织工程的演变，再生 医学和添加剂制造可以生成各种治疗细胞和组织 疾病诊断，治疗，预防和管理。组织模型和器官具有 成为更好地理解疾病并简化药物开发的一种方式。尽管 这一进展，相对于其他医疗产品的生物产品的高度复杂性要求 等效的高级转换和整合（尚未出现）导致 按需生产可靠，可扩展，健壮和可再现的构造组织。利用 这些最近的进步，一个新的戈登研究会议，题为“高级细胞和 组织生物制造：通过融合技术开发和创新”将 确定将刺激高级科学技术创新的差距和挑战 生物制造。会议将突出与行业壁ni的学术力量的交汇处 加速了将实验室发现转化为细胞和组织产品的工业规模生产。 开发启用技术和材料和细胞采购的新方法，过程建模 以及整合，组织生物制造自动化，在线感应和控制，组织 开发和成熟，产品验证和功能测定，细胞和组织制备， 法规，质量保证和劳动力培训对于促进增长和维持该领域至关重要。 会议将为整个范围或科学的生产互动提供一个平台， 初级调查人员和学生到该领域的领导者的工程。这样的互动将帮助他们 探索研究的新方向并在高级生物制造中建立职业。特别的 将注意提高研究人员之间的多样性并了解文化影响 这些新颖的干预措施。