Louisiana Clinical and Translational Science Center

路易斯安那州临床和转化科学中心

基本信息

批准号：
10677678
负责人：
JOHN P. KIRWAN
金额：
$ 400万
依托单位：
LSU PENNINGTON BIOMEDICAL RESEARCH CTR
依托单位国家：
美国
项目类别：
财政年份：
2012
资助国家：
美国
起止时间：
2012-08-15 至 2027-06-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10677678
关键词：
Academic Medical Centers Address Administrative Supplement Advisory Committees Applications Grants Area Award Bioinformatics Biomedical Research Biometry Black race COVID testing COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 testing COVID-19 vaccination Cardiovascular Diseases Center for Translational Science Activities Chronic Disease Clinic Clinical Clinical Research Clinical Sciences Clinical Trials Collaborations Communication Communities Dedications Development Diabetes Mellitus Disease Management Disparity Diverse Workforce Education Ensure Federally Qualified Health Center Funding Generations Goals Grant Growth Health Health Sciences Healthcare Healthcare Systems Hurricane Infrastructure Inosine Dialdehyde Institution Institutional Review Boards Investments Learning Long COVID Longterm Follow-up Louisiana Malignant Neoplasms Mission Modeling Obesity Outcome Patients Pediatric Hospitals Persons Positioning Attribute Post-Acute Sequelae of SARS-CoV-2 Infection Productivity Professional Education Provider Public Health Publications RADx Underserved Populations Research Research Infrastructure Research Personnel Resources Role Rural Scholars Program School Dentistry Scientist Services Structure System Teacher Professional Development Testing Time Training Translational Research Trust Underrepresented Minority Underserved Population United States National Institutes of Health Universities Vaccination Veterans Work clinical translation cohort community engagement coronavirus disease diversity and inclusion experience health disparity health equity health literacy high risk population improved investigator training minority communities mortality multidisciplinary operation pandemic disease precision medicine precision nutrition pressure programs recoverin protein recruit resilience response rural health clinic safety net skills social health determinants synergism underserved community virtual platform

项目摘要

Project Summary: Overall The Louisiana Clinical and Translational Science (LA CaTS) Center is a consortium of the major academic and biomedical research centers in the State of Louisiana. Pennington Biomedical Research Center is the lead institution and will continue to partner with Louisiana State University Health (LSUH)-New Orleans and Tulane University Health Sciences Center in this initiative. LSUH-Shreveport, LSU-A&M (Baton Rouge), Xavier University and Children's Hospital New Orleans, were early Research Partners in cycle 1. Southeast Louisiana Veterans Healthcare System, a newly opened University Medical Center in New Orleans ($1 billion State investment), Ochsner Health and the LSUH-NO School of Dentistry joined during cycle 2. The LA CaTS Center is growing a unified clinical translational science program for Louisiana based on the creation of synergistic programs and unparalleled collaboration from all the major academic and biomedical research institutions in the state. Since inception 9 years ago, the LA CaTS Center has: 1) successfully leveraged resources and expertise of multiple participating institutions to build a vibrant statewide research infrastructure; 2) developed highly synergistic and integrative collaborative programs; 3) implemented a systematic approach to clinical research across all institutions, that includes a new SMART IRB Reliance Model review; and 4) implemented a highly effective governance system based on an unprecedented level of trust between partners. LA CaTS is experiencing exponential growth in research productivity as assessed by key metrics including a three-fold increase in external grant awards, a more than two-fold increase in publications with authors acknowledging LA CaTS Center resources and services and over 600 researchers benefiting from and using our services. Notably, during a period that has been marked by unique and unprecedented challenges from COVID and then Hurricane Ida, LA CaTS has achieved, and in many cases exceeded, its stated objectives and projected milestones. Indeed, since the COVID pandemic hit Louisiana in March of 2020, LA CaTS has led multiple successful grant applications for Administrative Supplements and NOSI awards, notably to facilitate COVID testing and vaccinations in underserved Black communities through the RADx-UP program and most recently our partnership with the IDeA state ISCORE consortium on the national Long-COVID initiative - Post-Acute Sequelae of SARS-CoV-2 Infection (PASC)/RECOVER trial. However, we fully recognize that our work has only just begun, as we collectively address disparities and improve the lives of our citizens. It is also apparent, that slowly, but surely, we are impacting public health one project at a time! With new services proposed and the additional resources that will be added, our Center is uniquely positioned to devote our activities and resources to our major theme for the next 5-year cycle that will “address health disparities and improve the health outcomes of the citizens we serve”.

项目概要：总体路易斯安那州临床和转化科学 (LA CaTS) 中心是一个由主要学术机构组成的联盟路易斯安那州彭宁顿生物医学研究中心是领先的。机构并将继续与路易斯安那州立大学健康分校 (LSUH)-新奥尔良和杜兰分校合作路易斯安那州立大学什里夫波特大学健康科学中心、路易斯安那州立大学 A&M（巴吞鲁日）、泽维尔。大学和新奥尔良儿童医院是第一周期的早期研究合作伙伴。路易斯安那州东南部退伍军人医疗保健系统，新奥尔良新开设的大学医疗中心（州政府耗资 10 亿美元）投资），Ochsner Health 和 LSUH-NO 牙科学院在第二周期加入。洛杉矶 CatS 中心正在路易斯安那州制定一个统一的临床转化科学计划，该计划的基础是创造协同效应来自所有主要学术和生物医学研究机构的计划和无与伦比的合作自 9 年前成立以来，洛杉矶 CatS 中心已经：1) 成功地利用了资源和专业知识。多个参与机构建立充满活力的本土研究基础设施；2）高度发达协同和综合合作计划；3）实施系统的临床研究方法在所有机构中，包括新的 SMART IRB 信赖模型审查以及 4) 得到高度实施； LA CatS 建立在合作伙伴之间前所未有的信任基础上的有效治理体系。通过关键指标评估，研究生产力呈指数增长，包括三倍外部资助金额增加，作者满意洛杉矶的出版物数量增加两倍以上 CatTS 中心的资源和服务以及 600 多名研究人员受益于并使用我们的服务。在这段时期，新冠肺炎和飓风带来了独特且前所未有的挑战艾达，洛杉矶 CatTS 已经实现并在许多情况下超出了其既定目标和预计里程碑。事实上，自 2020 年 3 月新冠疫情袭击路易斯安那州以来，LA CatTS 已成功领导了多项资助申请行政补充和 NOSI 奖项，特别是为了促进新冠病毒检测和通过 RADx-UP 计划以及最近我们的与 IDeA 州 ISCORE 联盟就国家长期新冠病毒倡议 - 急性后遗症开展合作然而，我们充分认识到我们的工作只是刚刚完成。当我们共同解决不平等问题并改善我们公民的生活时，这一点就开始了。同样明显的是，慢慢地，但可以肯定的是，我们正在通过提出新的服务和额外的项目来影响公共卫生！随着资源的增加，我们中心具有独特的优势，可以将我们的活动和资源投入到我们的专业领域下一个五年周期的主题是“解决健康差距并改善人们的健康结果” 我们服务的公民。”