Expansion of the efficacy trial of Tele-Harm Reduction into a federally qualified health center operated syringe services program.

将减少远程伤害的功效试验扩展到联邦合格的健康中心运营的注射器服务计划。

• 批准号: 10656900
• 负责人: Hansel Emory Tookes
• 金额: $ 15.35万
• 依托单位: UNIVERSITY OF MIAMI SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-05-01 至 2025-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10656900
• 关键词: AIDS prevention; Academic Medical Centers; Acquired Immunodeficiency Syndrome; Address; Administrative Supplement; Anti-Retroviral Agents; Caring; Case Management; Centers for Disease Control and Prevention (U.S.); Climacteric; Communicable Diseases; Communities; County; Developed Countries; Diagnosis; Disease Outbreaks; Drug user; Enrollment; Ensure; Environment; Epidemic; Federally Qualified Health Center; Florida; Foundations; General Hospitals; Goals; HIV; HIV Infections; HIV Seropositivity; Harm Reduction; Health; Health system; Healthcare; Healthcare Systems; Hepatitis C; Hepatitis C Therapy; Hepatitis C virus; High Prevalence; Incidence; Injecting drug user; Intervention; Intervention Studies; Modeling; Needle-Exchange Programs; Outcome; Patients; Persons; Pharmaceutical Preparations; Play; Population; Provider; Research; Role; Site; Stigmatization; Substance Use Disorder; System; Trust; Universities; addiction; base; care delivery; care outcomes; combat; coronavirus disease; efficacy study; efficacy testing; efficacy trial; evidence base; experience; flexibility; implementation barriers; implementation facilitation; implementation facilitators; implementation strategy; implementation study; injection drug use; meetings; novel strategies; opioid use disorder; prevent; programs; response; service delivery; standard of care; syndemic; telehealth

PROJECT ABSTRACT This application is being submitted in response to PA-20-272 as an administrative supplement to DP2DA053720- 01 (PI: Tookes). The T-SHARP (Telehealth Solution to HIV and Addiction-Related Problems) trial will study the efficacy of the Tele-Harm Reduction intervention in 2 syringe services programs (SSPs) operated within academic medical centers, University of Miami/Jackson Health System and University of South Florida/Tampa General Hospital. The aims of this administrative supplement are 1) to expand the T-SHARP trial of the Tele- Harm Reduction intervention to a third site in Florida with a high prevalence of PWID with HIV and 2) to examine implementation barriers and facilitators to identify appropriate implementation strategies to facilitate implementation of the Tele-Harm Reduction intervention within a new contextual environment (a Federally Qualified Health Center based SSP). The third site will expand the existing trial to three of the seven Ending the HIV Epidemic jurisdictions in Florida (Miami-Dade, Hillsborough, and Broward Counties). This expansion of trial sites and study of the intervention implementation in a new context will ensure the study meets enrollment targets and that the intervention is feasible in varying SSP environments.

项目摘要 该申请正在响应PA-20-272提交，作为DP2DA053720-的管理补充 01（pi：tickes）。 T-SHARP（针对HIV和与成瘾有关的问题的远程医疗解决方案）试验将研究 在内部运行的2个注射器服务计划（SSP）中，电障碍干预的功效 迈阿密大学/杰克逊大学卫生系统和南佛罗里达大学/坦帕大学学术医疗中心 综合医院。这种行政补充的目的是1）扩大电信的T-sharp试验 对佛罗里达州第三个地点的损害减少干预，艾滋病毒的PWID患病率很高和2） 实施障碍和促进者，以确定适当的实施策略以促进 在新的上下文环境中实施减少电障碍干预（联邦政府 合格的健康中心SSP）。第三个站点将将现有试验扩展到七个结束的三项 佛罗里达州的艾滋病毒流行司法管辖区（迈阿密戴德，希尔斯伯勒和布劳沃德县）。试验的扩展 在新情况下对干预实施实施的站点和研究将确保研究达到入学目标 在不同的SSP环境中，干预是可行的。

项目成果

Prevalence of xylazine among people who inject drugs seeking medical care at a syringe services program clinic: Miami, Florida, 2023.

• DOI: 10.1016/j.dadr.2023.100209
• 发表时间: 2023-12
• 期刊: Drug and alcohol dependence reports
• 作者: Hauschild, Maia H;Warp, Peyton V;Tookes, Hansel E;Yakir, Ella;Malhotra, Bharat;Malik, Subul;Owens, Cyrus;Suarez, Edward Jr;Serota, David P;Bartholomew, Tyler S
• 通讯作者: Bartholomew, Tyler S

A Confirmed Case of Xylazine-Induced Skin Ulcers in a Person Who Injects Drugs in Miami, Florida, USA.

美国佛罗里达州迈阿密一例注射毒品者因甲苯噻嗪诱发皮肤溃疡的确诊病例。

• DOI: 10.21203/rs.3.rs-3194876/v1
• 发表时间: 2023
• 期刊: Research square
• 作者: Warp,PeytonV;Hauschild,Maia;Tookes,HanselE;Ciraldo,Katrina;Serota,DavidP;Cruz,Irasema
• 通讯作者: Cruz,Irasema

Adaptation of the Tele-Harm Reduction intervention to promote initiation and retention in buprenorphine treatment among people who inject drugs: a retrospective cohort study.

• DOI: 10.1080/07853890.2023.2182908
• 发表时间: 2023-12
• 期刊: Annals of medicine
• 影响因子: 4.4

Injection and Sexual Behavior Profiles among People Who Inject Drugs in Miami, Florida.

• DOI: 10.1080/10826084.2022.2083171
• 发表时间: 2022
• 期刊: SUBSTANCE USE & MISUSE
• 影响因子: 2
• 作者: Chueng, Teresa A.;Tookes, Hansel E.;McLaughlin, Megan;Arcaro-Vinas, Angela M.;Serota, David P.;Bartholomew, Tyler S.
• 通讯作者: Bartholomew, Tyler S.