Training Program in Neuroengineering and Medicine

神经工程和医学培训计划

• 批准号: 8854679
• 负责人: Brian Litt
• 金额: $ 23.35万
• 依托单位: UNIVERSITY OF PENNSYLVANIA
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-07-01 至 2020-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8854679
• 关键词: Medicine; Training Programs

 DESCRIPTION (provided by applicant): The aim of our new, multidisciplinary institutional training program, based in the Schools of Medicine and Engineering at the University of Pennsylvania, is to train pre-doctoral engineering students and physician postdoctoral fellows in Neuroengineering and its clinical translation. Disorders of the nervous system, such as stroke, epilepsy, Parkinson's disease, depression, dementia, and head trauma, constitute 35% of all disease and disability, and the burden is rising. There is an explosion of promising therapies for these disorders in new technologies to image, analyze, and modulate neural circuits, but translating these therapies from the laboratory to patients is a challenge. It requires talented engineers educated in clinical science and technically proficient physicians who speak the same language. Together these investigators must navigate a complex scientific, regulatory, and clinical landscape. Despite the huge demand, few formal, interdisciplinary Neuroengineering training programs exist. We propose a new program shared by the Penn Schools of Medicine and Engineering focused on Neuroengineering and Clinical Translation. Physician and Engineering trainees will together become fluent in cutting-edge technologies at the forefront of Neuroengineering, such as devices, neurostimulation, machine learning, and algorithm development; cloud computing, nanotechnology and materials science. They will innovate new therapies for human disease and gain a thorough understanding of the clinical, regulatory, and developmental environments necessary to safely bring new technologies to patients. The program's core is a group of collaborative, multidisciplinary faculty mentors in engineering and the clinical neurosciences. In addition to dedicated neuroengineering research, our training program includes: (1) a longitudinal mentored clinical experience for PhD candidates, (2) engineering lab immersion and tutorial for MD postdoctoral fellows, (3) formal courses and seminars in Engineering, Neuroscience and Medicine, (4) training in the proper conduct of research, and (5) workshops on professional and career development, including scientific writing, public presentations, grant writing, and laboratory management. The program will recruit from an excellent pool of ~50 MD fellows and 80-90 PhD students each year. This effort formalizes a collaboration that has trained an impressive array of Neuroengineering investigators over the past twelve years. The program, unique at Penn, leverages a superb research and training environment, including a compact campus where robust centers for Engineering, Medicine and Neuroscience all reside within two blocks of each other, united through Penn's new Center for Neuroengineering and Therapeutics.

 描述（由申请人提供）：我们新的多学科机构培训计划位于宾夕法尼亚大学医学与工程学院，旨在培训神经工程及其临床翻译方面的博士前工程学生和医师博士后研究员神经系统疾病，如中风、癫痫、帕金森病、抑郁症、痴呆和头部外伤，占所有疾病和残疾的 35%，而且这种疾病的负担正在不断增加。针对这些疾病的有希望的治疗方法出现了激增。新技术对神经回路进行成像、分析和调节，但将这些疗法从实验室转移到患者身上是一项挑战，需要受过临床科学教育的优秀工程师和技术熟练的医生，这些研究人员必须共同驾驭。尽管需求巨大，但很少有正式的、跨学科的神经工程培训项目，我们建议宾夕法尼亚大学医学与工程学院共享一个专注于神经工程和临床翻译的新项目。在一起精通神经工程前沿的尖端技术，如设备、神经刺激、机器学习和算法开发、纳米技术和材料科学；他们将为人类疾病创新新疗法，并深入了解临床、安全地将新技术带给患者所需的监管和发展环境该计划的核心是一群工程和临床神经科学领域的协作、多学科教师导师。除了专门的神经工程研究外，我们的培训计划还包括：（1）纵向培训。指导的博士生的临床经验，(2) 医学博士后研究员的工程实验室浸入式学习和辅导，(3) 工程、神经科学和医学方面的正式课程和研讨会，(4) 正确进行研究的培训，以及 (5) 研讨会该项目每年将从约 50 名医学博士研究员和 80-90 名博士生中招募人才，以培养专业和职业发展，包括科学写作、公开演讲、资助写作和实验室管理。令人印象深刻的一系列过去十二年来，该项目在宾夕法尼亚大学独一无二，利用了一流的研究和培训环境，包括一个紧凑的校园，强大的工程、医学和神经科学中心都位于彼此相邻的两个街区内，通过宾夕法尼亚大学的新中心联合起来。用于神经工程和治疗学。