Administrative Core: Center for Diagnostic and Therapeutic Strategies in Pancreatic Cancer

行政核心：胰腺癌诊断和治疗策略中心

• 批准号: 10666692
• 负责人: Sanku Mallik
• 金额: $ 56.22万
• 依托单位: NORTH DAKOTA STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-03-01 至 2027-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10666692
• 关键词: Acceleration; Address; Advisory Committees; American Association of Cancer Research; American Cancer Society; Animal Model; Biomedical Research; Budgets; Cancer Biology; Cell model; Clinical; Collaborations; Core Facility; Dedications; Department of Defense; Diagnostic; Disease; Educational workshop; Ensure; Environment; Equilibrium; Equipment; Experimental Designs; Extramural Activities; Faculty; Family; Fostering; Foundations; Funding; Funding Mechanisms; Goals; Grant; Infrastructure; Leadership; Malignant Neoplasms; Malignant neoplasm of pancreas; Manuscripts; Mentors; Modeling; National Institute of General Medical Sciences; North Dakota; Organization and Administration; Peer Review; Personnel Management; Persons; Phase; Pilot Projects; Preparation; Process; Published Comment; R24; Recommendation; Reporting; Research; Research Infrastructure; Research Personnel; Research Project Grants; Resources; Science; Scientist; Secure; Senior Scientist; Services; Strategic Planning; Structure; Technical Expertise; Therapeutic; Training; Translational Research; United States National Institutes of Health; Universities; Work; Writing; career; career development; competitive environment; improved; meetings; member; operation; organizational structure; peer; programs; recruit; skills; success; symposium; translational scientist; translational study; virtual

Project Summary: The administrative core will oversee the coordination of the "Center for Diagnostic and Therapeutic Strategies in Pancreatic Cancer" (CDTSPC). It will provide essential resources to administer the organizational structure and ensure the success of CDTSPC at North Dakota State University (NDSU). The Center will continue to develop research programs led by Junior Investigators, promote biomedical translational research, enhance the research infrastructure at NDSU, and provide enhanced mentoring to increase the number of NIH-funded research grants. The goals of this Center are to develop self-sustaining research programs by Junior Investigators, increase the number of NIH-funded researchers, and expand the University's research capability on a disease-specific program, particularly in pancreatic cancer. These goals will be accomplished through the following Specific Aims. Aim 1: Continue to provide efficient leadership and administrative structure for the successful operations of CDTSPC. The Administrative Core will ensure that the Junior Investigators are supported by all Core Facilities and equipment needed to ensure rapid research progress. The Center will conduct formative and summative assessments of all projects, Core Facilities, and the career development-mentoring plan. In addition, the Administrative Core will be responsible for budget management, External Advisory Committee (EAC) meetings, symposia, and yearly reports to NIGMS. Aim 2: Implement an enhanced, result-oriented, multi-tier mentoring strategy to accelerate the career development of the Junior Investigators. The Administrative Core will implement an enhanced mentoring model that identifies two external and one internal mentor and one peer advisor (mentoring team) for each Junior Investigator. The mentoring team will address future research directions, organization and presentation of manuscripts, strategies for writing competitive proposals, and proposal review before submission. Furthermore, Junior Investigators will engage with CDTSPC's Translational Science Liaison and receive mentoring on the translational aspects of their projects. Aim 3: Enhance biomedical research infrastructure at NDSU. The Administrative Core will competitively recruit a replacement once a Junior Investigator graduates as an independent investigator through a campus-wide proposal solicitation, external peer review, recommendation of the EAC, followed by NIH approval. Aim 4: Accomplish the self-sustaining status of CDTSPC. All investigators will compete for extramural research grants from federal and non-federal resources in the competitive field of cancer biology. In addition, the Administrative core will ensure timely completion of the CDTSPC milestones.

项目摘要： 行政核心将监督“诊断和治疗策略中心的协调 胰腺癌”（CDTSPC）。它将提供重要的资源来管理组织结构和 确保CDTSPC在北达科他州立大学（NDSU）取得成功。中心将继续发展 由初级研究人员领导的研究计划，促进生物医学转化研究，增强研究 NDSU的基础设施，并提供增强的指导，以增加NIH资助的研究赠款的数量。 该中心的目标是制定初级研究人员的自我维持研究计划，增加 NIH资助的研究人员的数量，并扩大大学的研究能力 程序，特别是在胰腺癌中。这些目标将通过以下特定来实现 目标。目标1：继续为成功的运营提供有效的领导力和行政结构 CDTSPC。行政核心将确保初级调查人员得到所有核心设施的支持 以及确保快速研究进展所需的设备。该中心将进行形成性和总结性 评估所有项目，核心设施和职业发展计划。另外， 行政核心将负责预算管理，外部咨询委员会（EAC）会议， 专题讨论会，并年度向尼布姆斯报告。目标2：实施增强的，面向结果的，多层指导 加速初级调查人员职业发展的策略。行政核心将实施 一个增强的指导模型，可以识别两个外部和一名内部指导者和一名同伴顾问 （指导团队）每个初级调查员。指导团队将解决未来的研究方向， 手稿的组织和陈述，编写竞争建议的策略以及提案审查 提交之前。此外，初级调查人员将与CDTSPC的转化科学联络 并在其项目的翻译方面接受指导。目标3：增强生物医学研究 NDSU的基础设施。一旦初级，行政核心将竞争招募替换 调查员通过校园范围的提案招标作为独立研究员毕业，外部 同行评审，EAC的建议，然后进行NIH批准。目标4：完成自我维持的 CDTSPC的状态。所有调查人员将竞争联邦和非联邦的校外研究补助 癌症生物学竞争领域的资源。此外，行政核心将确保及时 CDTSPC里程碑的完成。