The Center for Innovation and Translation of Point of Care Technologies for Equitable Cancer Care (CITEC) - Administrative Core

公平癌症护理护理点技术创新与转化中心 (CITEC) - 行政核心

• 批准号: 10715741
• 负责人: Rebecca R. Richards-Kortum
• 金额: $ 15.04万
• 依托单位: RICE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-13 至 2028-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10715741
• 关键词: Acceleration; Address; Advisory Committees; Algorithms; Anus; Brazil; Budgets; Carcinoma; Caring; Cervix Uteri; Cessation of life; Clinical; Collaborations; Colon; Communication; Communities; Data; Decision Making; Development; Diagnostic; Disease; Early Diagnosis; Engineering; Ensure; Epithelium; Equity; Esophagus; Evaluation; Feedback; Funding; Gastrointestinal tract structure; Goals; Imaging Device; In Vitro; Incidence; Individual; Inequity; Instruction; Knowledge; Leadership; Lesion; Malignant Neoplasms; Mission; Molecular; Mozambique; Office of Administrative Management; Oral cavity; Organ; Performance; Point of Care Technology; Policies; Process; Productivity; Protocols documentation; Public Health; Rectum; Research; Research Personnel; Resources; Scientist; Screening for cancer; Site; Stomach; Structure; System; Techniques; Technology; Testing; Tissues; Translations; United States National Institutes of Health; Voting Right; Work; biomedical imaging; cancer care; cancer prevention; commercialization; conflict resolution; design; imaging system; improved; in vivo imaging; in-vitro diagnostics; industry partner; innovation; manufacture; member; mortality; multidisciplinary; premalignant; prevent; programs; rectal; sensor; socioeconomic disparity; tool

Abstract: Cancers arising in epithelial tissue account for 80‐90% of all cases. Many epithelial cancers could be prevented or cured by detecting and treating pre‐cancerous lesions and early stage disease. A number of POC technologies have shown promise to improve cancer screening and early detection of epithelial precancer and cancer, including both in vitro and in vivo imaging tools, and molecular sensors. However, development and translation of POC technologies are slowed by multiple technical and clinical barriers. The Center for Innovation and Translation of Point‐of‐Care Technologies for Equitable Cancer Care (CITEC) is structured to offer “one‐stop shopping” to address these barriers. CITEC will support and accelerate the development, delivery and equitable use of affordable, effective and accessible POC technologies to screen and/or detect epithelial precancer and early cancer. The Administrative Core will provide overall project oversight and management to ensure that all CITEC cores function at a high level, that cores collaborate effectively to achieve the overall goals of CITEC, and that CITEC is responsive to and synergistic with the goals of the overall POCTRN network. The first aim of the Administrative Core is to establish and manage the administrative structure, governance policies, decision making, budget management, and conflict resolution processes and communications plans for the Center. The CITEC program will be overseen by a CITEC Steering Committee, consisting of the PD/PIs and co‐leads of Cores with equal voting rights. The CITEC Steering Committee will review progress of cores and individual projects, develop collaborative protocols, identify technological impediments to progress, select strategies to surmount them and identify opportunities for sharing techniques and tools developed within individual projects. The Administrative Core will also have primary responsibility for interactions with NIH and will work with NIH to advance efforts to reach the goals of POCTRN. The second aim of the Administrative Core is to work to continuously evaluate and improve CITEC, partnering with the leadership of the Cores to gather and analyze data to identify challenges in optimizing the impact of CITEC activities. To achieve this aim, the Administrative Core will assist CITEC Cores to build multidisciplinary partnerships; to ensure inclusion of a diverse community of partners and stakeholders; and to evaluate performance and guide performance improvement. The AC will develop review mechanisms to ensure that project resources are used effectively to accelerate the development, translation and equitable implementation of POC technologies to improve cancer screening and early detection. The AC will establish an External Advisory Committee; CITEC performance data will be shared with the External Advisory Committee and, with their feedback, will ensure that CITEC engages in effective continuous quality improvement. In short, the Administrative Core will support robust, productive and efficient interactions between CITEC members, funded investigators, the POCTRN network and relevant stakeholders.

抽象的： 在上皮组织中产生的癌症占所有病例的80-90％。可以预防或治愈许多上皮癌 通过检测和治疗癌前病变和早期疾病。许多POC技术已显示 有望改善癌症筛查和早期检测上皮预科剂和癌症，包括体外和IN 体内成像工具和分子传感器。但是，POC技术的开发和翻译被放缓 多个技术和临床障碍。创新和翻译中心护理技术的技术 公平癌症护理（CETEC）的结构是提供“一站式购物”来解决这些障碍。 Citec将支持并 加快价格合理，有效且可访问的POC技术的开发，交付和公平使用 和/或检测上皮预科剂和早期癌症。行政核心将提供整体项目监督和 管理层以确保所有Citec核心在高水平上发挥作用，核心有效地协作以实现总体 Citec的目标，以及Citec对整个POCTRN网络的目标响应和协同作用。 行政核心的第一个目的是建立和管理行政结构，治理政策， 该中心的决策，预算管理以及冲突解决过程和通信计划。 CETEC计划将由Citec指导委员会监督，由PD/PI和核心的共同领导者组成 投票权。 CETEC指导委员会将审查核心和个别项目的进度，开发协作 协议，确定进步的技术障碍，选择策略来克服它们并确定机会 用于共享各个项目中开发的技术和工具。行政核心也将有主要 与NIH互动的责任，并将与NIH合作，以促进实现Poctrn目标的努力。 行政核心的第二个目的是努力不断评估和改善Citec，与 核心的领导地收集和分析数据，以确定优化Citec活动影响的挑战。到 实现这一目标，行政核心将有助于Citec Core建立多学科合作伙伴关系；确保包容 由伙伴和利益相关者组成的潜水员社区；并评估性能和指导性能的改善。 AC将开发审查机制，以确保有效地使用项目资源来加速 POC技术的开发，翻译和公平实施以改善癌症筛查和早期 检测。 AC将成立外部咨询委员会； CETEC性能数据将与外部咨询共享 委员会以及他们的反馈将确保Citec从事有效的持续质量改进。 简而 资助的研究人员，Poctrn网络和相关利益相关者。