University of New Mexico Cancer Center Support Grant

新墨西哥大学癌症中心支持补助金

基本信息

批准号：
10514685
负责人：
Alan E Tomkinson
金额：
$ 25万
依托单位：
UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR
依托单位国家：
美国
项目类别：
财政年份：
2005
资助国家：
美国
起止时间：
2005-09-26 至 2026-08-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10514685
关键词：
Advanced Malignant Neoplasm American Indians Award Behavioral Black race Cancer Burden Cancer Center Cancer Center Support Grant Cancer Control Cancer Control Research Catchment Area Characteristics Clinic Clinical Clinical Research Clinical Trials Network Communities Community Clinical Oncology Program Community Health Community Health Systems Community Outreach Comprehensive Cancer Center Contracts Data Environmental Exposure Etiology Evaluation Foundations Funding Genetic Genomic medicine Goals Grant Growth Health Health system Hispanic Human Papillomavirus Incidence Informatics Infrastructure Interdisciplinary Study Intervention Journals Laboratories Latino Leadership Legal patent Malignant Neoplasms Mentors Mexican Minority Mission NCI Center for Cancer Research New Mexico Not Hispanic or Latino Oncology Pattern Peer Review Persons Population Population Sciences Positioning Attribute Provider Publications Registries Research Research Infrastructure Research Institute Research Personnel Resource Sharing Rural Rural Population SEER Program Source Strategic Planning Therapeutic Training Training Programs Training and Education Translating Translational Research Translations Trust Underrepresented Minority Universities Visualization anticancer research base cancer care cancer clinical trial cancer education cancer genome cancer health disparity cancer prevention care delivery caucasian American cellular oncology community engagement community intervention data modeling early phase trial environment related cancer ethnic minority genome sequencing hispanic community member molecular oncology mortality mortality disparity multi-ethnic novel patient engagement predictive modeling programs racial and ethnic recruit respiratory screening social socioeconomics translational research program tribal Nation tumor registry underserved minority

项目摘要

OVERALL COMPONENT: THE UNIVERSITY OF NEW MEXICO COMPREHENSIVE CANCER CENTER PROJECT SUMMARY / ABSTRACT Since achieving designation as a NCI Cancer Center in 2005 and a NCI Comprehensive Cancer Center in 2015, the University of New Mexico Comprehensive Cancer Center (UNMCCC) and its Consortium Partner, Lovelace Biomedical/The Lovelace Respiratory Research Institute (LRRI), have built a single transdisciplinary cancer- focused research enterprise across its catchment area, the State of New Mexico (NM). The distinguishing characteristics of the UNMCCC include: 1) the multiethnic, urban/rural populations that it serves - primarily Hispanic/Latino, non-Hispanic White, American Indian, and Black - with strikingly different patterns of cancer incidence and mortality, tremendous cancer health disparities, and profound socioeconomic vulnerabilities; 2) deep engagement and unique research and education and training partnerships with American Indian (AI) Nations and Hispanic (H) communities; 3) statewide cancer surveillance, screening registries, and unique tele- mentoring infrastructures that facilitate cancer control research; and 4) a statewide clinical trials network, funded as a Minority/Underserved NCI Community Oncology Research Program, engaging the majority of the state's oncology providers. The UNMCCC mission is to reduce the cancer burden and overcome the tremendous cancer health disparities of the NM catchment area through ground-breaking transdisciplinary research, translation of discoveries to clinical and community interventions, impactful bi-directional community engagement, training of a more diverse cancer workforce, and delivery of exceptional cancer care. With extensive strategic planning and evaluation, the UNMCCC significantly restructured and enhanced its Leadership, 3 Research Programs, 9 Shared Resources, and clinical research infrastructure to assure the Center's continued growth. Since 2015, 33 new Members were recruited and 23 Endowed Positions created. The Center's 102 Members are clustered into 3 interdisciplinary, highly translational Research Programs (Cancer Control & Population Sciences, Cellular & Molecular Oncology, and Cancer Therapeutics), supported by $36,196,038 in annual direct cancer-relevant funding, of which $27,542,340 is peer-reviewed and $8,245,544 is NCI. With $3,009,657 in additional NCI contracts and supplements, total annual NCI funding to the Center is $11,255,201. UNMCCC research is highly interactive and impactful (with collaborative publications ranging from 34-60% in its Research Programs, 16% of 930 publications in high impact journals, 136 patents filed, and 10 new companies launched). Four UNMCCC discoveries were translated to early phase trials, one of which is now a national NCTN NRG trial. Of 1361 accruals in 2019, 40% of interventional treatment accruals were racial/ethnic minorities (29% H; 6% AI), as were 55% of interventional non-treatment accruals (33% H; 12% AI). Among 530 trainees, 72% were minority/diverse scholars. With the awarding of 27 collaborative grants (including a NCI Participant Engagement-Cancer Genome Sequencing Research Center and 3 focused on environmental exposure and cancer causation, all engaging Tribal Nations), the UNMCCC will continue to have a profound impact on its catchment area and the nation.

整体组成部分：新墨西哥大学综合癌症中心项目概要/摘要自 2005 年被指定为 NCI 癌症中心和 2015 年被指定为 NCI 综合癌症中心以来，新墨西哥大学综合癌症中心 (UNMCCC) 及其联盟合作伙伴 Lovelace 生物医学/洛夫莱斯呼吸研究所 (LRRI) 建立了一个单一的跨学科癌症- 新墨西哥州 (NM) 的集中研究企业。与众不同的 UNMCCC 的特点包括： 1) 它所服务的多民族、城市/农村人口——主要是西班牙裔/拉丁裔、非西班牙裔白人、美洲印第安人和黑人 - 癌症模式截然不同发病率和死亡率、巨大的癌症健康差异以及深刻的社会经济脆弱性； 2）与美洲印第安人 (AI) 的深入接触和独特的研究、教育和培训合作伙伴关系民族和西班牙裔 (H) 社区； 3) 全州范围的癌症监测、筛查登记和独特的远程监测指导促进癌症控制研究的基础设施； 4) 资助的全州临床试验网络作为少数群体/服务不足的 NCI 社区肿瘤学研究计划，吸引了该州的大多数人肿瘤学提供者。 UNMCCC 的使命是减轻癌症负担并战胜巨大的癌症通过突破性的跨学科研究，翻译新墨西哥州流域的健康差异临床和社区干预措施的发现、有影响力的双向社区参与、培训更加多元化的癌症劳动力，以及提供卓越的癌症护理。凭借广泛的战略规划和评估，UNMCCC 显着重组并增强了其领导力，3 个研究项目，9 共享资源和临床研究基础设施，以确保中心的持续发展。自 2015 年以来，33 招募了新会员并创建了 23 个赋予职位。该中心的 102 名成员分为 3 个跨学科、高度转化的研究项目（癌症控制与人口科学、细胞与分子肿瘤学和癌症治疗），由年度直接癌症相关资金 36,196,038 美元支持资金，其中 27,542,340 美元经过同行评审，8,245,544 美元来自 NCI。额外 NCI 金额为 3,009,657 美元合同和补充材料，NCI 每年向该中心提供的资金总额为 11,255,201 美元。 UNMCCC的研究高度互动性和影响力（其研究项目中合作出版物的比例为 34-60%，其中 16% 在高影响力期刊上发表了 930 篇文章，申请了 136 项专利，成立了 10 家新公司）。四个UNMCCC 这些发现已转化为早期试验，其中一项试验现已成为国家 NCTN NRG 试验。共 1361 个 2019 年的应计收入中，40% 的介入治疗应计收入来自少数族裔/族裔（29% H；6% AI），同样， 55% 的介入非治疗应计费用（33% H；12% AI）。在 530 名学员中，72% 是少数族裔/多元化人士学者。获得 27 项合作资助（包括 NCI 参与者参与癌症基因组测序研究中心和 3 个重点关注环境暴露和癌症因果关系，所有这些都非常吸引人部落国家），UNMCCC 将继续对其辖区和国家产生深远的影响。