University of New Mexico Cancer Center Support Grant

新墨西哥大学癌症中心支持补助金

基本信息

批准号：
9765170
负责人：
Alan E Tomkinson
金额：
$ 224.6万
依托单位：
UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR
依托单位国家：
美国
项目类别：
财政年份：
2005
资助国家：
美国
起止时间：
2005-09-26 至 2021-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9765170
关键词：
Address Adolescent and Young Adult Advisory Committees Aftercare American Indians Area Behavior Therapy Behavioral Bone Marrow Stem Cell Transplantation Cancer Biology Cancer Burden Cancer Center Cancer Center Support Grant Cancer Control Cancer Control Research Cancer Control Research Program Cancer Intervention Cancer Research Project Cancer Survivorship Catchment Area Centers for Disease Control and Prevention (U.S.)Cervical Characteristics Clinic Clinical Clinical Research Clinical Trials Network Collaborations Colorectal Cancer Communities Community Networks Comprehensive Cancer Center Cultural Diversity Development Diagnosis Diagnostic Direct Costs Doctor of Philosophy Early Diagnosis Endometrial Carcinoma Epigenetic Process Etiology Evaluation Faculty Fostering Funding Genetic Genomics Geography Goals Health Health Professional Health system Healthcare Systems Hispanics Human Papilloma Virus Vaccination Improve Access Incidence Informatics Institutes Institution Interdisciplinary Study Intervention Intervention Studies Laboratories Latino Life Style Malignant Neoplasms Malignant neoplasm of lung Mentors Mexican Mission Modeling Molecular Epidemiology Morbidity - disease rate National Cancer Institute New Mexico Not Hispanic or Latino Oncologist Oncology Group Outcome Outcome Study Pattern Peer Review Pharmacology Phase Physicians Population Population Sciences Prevention Prevention strategy Primary carcinoma of the liver cells Provider Publications Pueblo Race Race Registries Research Research Institute Research Personnel Research Support Research Training Resource Sharing Resources Risk Risk Reduction Schools Science Scientific Advances and Accomplishments Scientist Signal Transduction Social Identification Surveillance Program Technology Testing Therapeutic Therapeutic Clinical Trial Therapeutic Intervention Training Training Programs Training and Education Translating Treatment outcome Tribes Underrepresented Minority Underserved Population United States Indian Health Service Universities Work anticancer research base behavior measurement cancer care cancer clinical trial cancer genetics cancer health disparity cancer therapy care delivery cervical cancer prevention clinical care clinical translation community intervention cooking design gene environment interaction graduate student improved laboratory facility malignant breast neoplasm medically underserved melanoma member mortality mortality disparity neuro-oncology novel outreach program programs ranpirnase recruit research facility respiratory risk variant screening screening program social socioeconomics survivorship synergism targeted delivery telehealth tumor undergraduate student working group

项目摘要

DESCRIPTION (provided by applicant): The Cancer Control (CaC) Research Program is a newly restructured transdisciplinary program that serves as the hub for cancer control and population science research within the University of New Mexico Cancer Center (UNMCC) and the State of New Mexico (NM), our catchment area. The Program's overall goal is to reduce cancer incidence, morbidity, and mortality, particularly in the unique multiethnic and underserved populations of NM. Disparities research is a cross-cutting theme that fosters scientific focus and synergy across the research areas. Through vigorous strategic program planning and evaluation, recruitment of 9 new investigators to enhance expertise in molecular epidemiology and behavioral/community intervention, and guidance of the UNMCC External Advisory Committee, the CaC Program is now focused on three areas of cancer research: 1) Risk Prediction and Risk Reduction; 2) Screening; and 3) Post-Diagnosis Outcomes and Survivorship. Unique scientific strengths include research addressing disparities (geographic, race/ethnic, socioeconomic, medically underserved), particularly in etiologic, outcome, and intervention studies in Hispanics. By drawing on established and new partnerships, the Program is also building research that addresses American Indian cancer disparities and priorities identified by NM Tribes, Pueblos, and Indian Nations. Major scientific accomplishments in Risk Prediction and Risk Reduction include the identification of social, lifestyle, and genetic factors associated with lung cancer risk; gene-environment interactions in melanoma risk; and development and dissemination of a novel telehealth strategy for the prevention of hepatocellular cancer. In Screening, members have developed a statewide surveillance program of screening and diagnosis for cervical pre-cancer and cancer that informs real- world cervical cancer prevention through human papilloma virus (HPV) vaccination, screening practice and outcomes. Members have also identified barriers to use of early detection tests in colorectal cancer and have developed strategies to overcome these barriers to improve screening in underserved populations. In Post- Diagnosis Outcomes and Survivorship, members have identified factors that contribute to disparities in post- treatment outcomes and survivorship in endometrial and breast cancer and are developing interventions. Led by Linda Cook, Ph.D. and Anita Kinney, Ph.D., RN, the CaC Program is comprised of 28 members (19 full and 9 associate) from 7 UNM schools and departments, the Lovelace Respiratory Institute, and the Indian Health Service Unit of the Centers for Disease Control whose work is supported by $19,276,863 million in annual direct cost funding, of which $15,429,911 million is peer-reviewed and $3,137,820 million is from NCI as of 9/1/2014. The discoveries made in this Program have resulted 294 publications, of which 19% are intra-programmatic collaborations and 16% are inter-programmatic collaborations; with a total UNMCC and external collaborative publication level of 30% and 80%, respectively.

描述（由申请人提供）：癌症控制 (CaC) 研究计划是一个新重组的跨学科计划，作为新墨西哥大学癌症中心 (UNMCC) 和新墨西哥州癌症控制和人口科学研究的中心(NM)，我们的服务区域，该计划的总体目标是降低癌症发病率、发病率和死亡率，特别是在新墨西哥州独特的多种族和服务不足的人群中。通过积极的战略计划规划和评估、招募 9 名新研究人员以增强分子流行病学和行为/社区干预方面的专业知识，以及 UNMCC 外部咨询委员会的指导，CaC 计划现在的重点是促进跨研究领域的科学重点和协同作用。癌症研究的三个领域：1) 风险预测和风险降低；2) 筛查；3) 诊断后结果和生存率，包括解决差异的研究。（地理、种族/族裔、社会经济、医疗服务不足），特别是在西班牙裔的病因、结果和干预研究方面，该计划还利用已建立的和新的伙伴关系开展研究，解决美洲印第安人癌症差异和 NM 确定的优先事项。部落、普韦布洛和印第安民族在风险预测和降低风险方面的主要科学成就包括识别与肺癌风险以及黑色素瘤的发展和传播相关的社会、生活方式和遗传因素；预防肝细胞癌的新型远程医疗策略 In Screening 成员制定了一项省级宫颈癌前病变和癌症筛查和诊断监测计划，通过人乳头状瘤病毒 (HPV) 疫苗接种、筛查为现实世界的宫颈癌预防提供信息。成员们还确定了结直肠癌早期检测检测的障碍，并制定了克服这些障碍的策略，以改善服务不足人群的筛查。在诊断后结果和生存率中，成员们确定了影响结直肠癌的因素。 CaC 项目由 Linda Cook 博士和 Anita Kinney 博士、注册护士领导，由 28 名成员（19 名正式成员和 19 名成员）组成。 9 名助理）来自新墨西哥州 7 个学校和部门、洛夫莱斯呼吸研究所和疾病控制中心印第安人卫生服务部门，其工作得到了 192,768.63 亿美元的年度直接成本支持截至 2014 年 9 月 1 日，该计划中的发现已产生 294 篇出版物，其中 19% 为项目内合作，16% 为项目间合作，其中 15,429,911 百万美元经过同行评审，3,137,820 百万美元来自 NCI。项目合作；UNMCC 和外部合作出版水平分别为 30% 和 80%。