Administrative Core for SWOG SDMC

SWOG SDMC 的管理核心

• 批准号: 10643702
• 负责人: Michael L. LeBlanc
• 金额: $ 141.3万
• 依托单位: FRED HUTCHINSON CANCER CENTER
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-04-17 至 2025-02-28
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10643702
• 关键词: Advisory Committees; Area; Biometry; Child; Clinical Data; Clinical Medicine; Clinical Sciences; Clinical Trials; Clinical Trials Design; Collaborations; Communities; Data; Data Analyses; Data Coordinating Center; Decision Making; Development; Ensure; Faculty; Fred Hutchinson Cancer Research Center; Genomics; Homes for the Aged; Hospitals; Immunotherapy; Leadership; Methods; Monitor; NCI Center for Cancer Research; National Clinical Trials Network; Research; Research Methodology; Research Personnel; Safety; Southwest Oncology Group; Statistical Methods; anticancer research; biobank; biological specimen archives; clinical development; clinical trial analysis; data management; data science management; data sharing; design; interest; meetings; member; multidimensional data; novel; organizational structure; precision medicine; programs; statistics; translational medicine; user-friendly; working group

Project Summary/Abstract Administrative Core The SWOG SDMC Administrative Core is the home of the senior administrative leadership team of the SDMC; it provides integration between the statistics and data management components. The senior administrative team (in partnership with the SWOG Group Chair and NCI) sets priorities regarding the development of clinical trial designs, monitoring, and data management for SWOG within the NCTN. The SWOG SDMC is located at the Fred Hutchinson Cancer Research Center and Cancer Research And Biostatistics, which are both non-profit research organizations. The SDMC contributes to the collective management of the NCTN Program by participating in the NCI Scientific Steering Committees, associated Task Forces, Working Groups, and other NCI initiatives. In addition, the Administrative Core provides data from completed clinical trials in a timely and user-friendly format for public access. The staff help in the interpretation of clinical data and facilitate the approved use of NCTN program specimens archived by SWOG at the centralized biobank at Children's Nationwide Hospital. SDMC faculty and staff have extensive collaborations with other NCTN Network Groups for the design, conduct, and analysis of clinical trials. They also have significant collaborations with other NCI-sponsored programs, especially the NCORP program. The faculty contribute to new statistical methods developments for clinical trials design, data monitoring and analysis, and genomic analysis, which is useful within the NCTN and also widely applicable to the greater cancer research community. Areas of interest include new methods for precision medicine, immunotherapy studies, and high-dimensional data analysis.

项目摘要/摘要 行政核心 SWOG SDMC行政核心是SDMC高级行政领导团队的所在地； 它提供了统计和数据管理组件之间的集成。高级行政团队 （与Swog Group主席和NCI合作）将有关临床试验发展的优先事项设定 NCTN中的Swog的设计，监视和数据管理。 Swog SDMC位于 弗雷德·哈钦森癌症研究中心以及癌症研究与生物统计学，它们都是非营利组织 研究组织。 SDMC通过参加NCI Scientific，为NCTN计划的集体管理做出了贡献 指导委员会，相关工作队，工作组和其他NCI计划。另外， 行政核心提供及时且用户友好的公众临床试验中的数据 使用权。员工帮助解释临床数据并促进批准使用NCTN计划 在儿童医院的集中生物库中，由Swog存档的标本存档。 SDMC教职员工与其他NCTN网络组进行了广泛的合作，以进行设计，行为， 和临床试验的分析。他们还与其他NCI赞助的程序进行了重要的合作， 特别是NCORP程序。 该教师为临床试验设计，数据监测和 分析和基因组分析，在NCTN中有用，也广泛适用于更大的癌症 研究社区。感兴趣的领域包括用于精密医学，免疫疗法研究和 高维数据分析。