Administrative Core

行政核心

• 批准号: 10388080
• 负责人: MATTHEW J SILVA
• 金额: $ 30.94万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-04-15 至 2024-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10388080
• 关键词: Advisory Committees; Animal Model; Applications Grants; Award; Biological; Biological Testing; Biology; Biometry; Collaborations; Communication; Communities; Consult; Development; Disease; Electronic Mail; Ensure; Environment; Evaluation; Event; Fostering; Functional disorder; Funding; Genetic Models; Goals; Grant; Interdisciplinary Study; Internal Medicine; Intervention; Leadership; Maintenance; Medicine; Mouse Strains; Musculoskeletal; Newsletter; Orthopedic Surgery; Performance; Publications; Recording of previous events; Research; Research Design; Research Personnel; Resources; Saints; Seeds; Series; Services; Social Network; Time; Universities; University resources; Washington; Work; base; cost effective; experience; interest; member; mouse genetics; news; next generation; operation; organizational structure; outreach; programs; social media; symposium; synergism; web site

Summary – Administrative Core (A) The long-term goals of the Washington University in Saint Louis (WUSTL) Resource-Based Center for Musculoskeletal Biology and Medicine (a.k.a., the “Center”) are to advance musculoskeletal research towards a better understanding of the biological basis of disease, and to develop and test biologically based interventions. We represent a Research Community of 81 investigators with $66 million in annual funding. A strength of our Research Community is in the use of animal models. Therefore, the overall objective for the Center and its Administrative Core is to support the development, implementation and evaluation of animal models for musculoskeletal biology and medicine. We will pursue this objective through our Leadership activities and Enrichment Program. The Administrative Core will provide leadership of the Center through a transparent organizational structure. We will coordinate all Center communications to our Research Community and the broader WUSTL community. We will participate in outreach activities and partnerships with other campus centers and programs to represent musculoskeletal research interests. We will provide guidance and oversight of the Research Cores to ensure that they are accessible, cost-effective and state- of-the-art. Through regular evaluation of utilization and performance, we will ensure that the Cores have strong impact locally and nationally. Since 2009, we have supported 343 publications that have been cited 6687 times. We propose a multi-faceted Enrichment Program to sustain and enhance the environment for musculoskeletal research at WUSTL, and to foster the development of the next generation of musculoskeletal investigators. Through a Pilot & Feasibility (P&F) Grant Program we will provide seed funding for meritorious projects that have potential to build to larger grant proposals, and that provide critical support to Early Stage Investigators or those new to musculoskeletal research. Since its inception, P&F Program awardees have earned 21 external grant awards on work related to their pilot grants. We will also provide numerous opportunities for exchange of new ideas and findings, through research and educational seminars, symposia and networking events. Lastly, we will support rigorous research approaches by providing expert consulting on the use of mouse genetic models, as well as study design and biostatistics. In summary, we will provide essential support for our Research Community to develop, implement and evaluate animal models for musculoskeletal biology and medicine, while fostering development of the next generation of musculoskeletal investigators.

总结——行政核心（A） 圣路易斯华盛顿大学 (WUSTL) 资源中心的长期目标 肌肉骨骼生物学和医学（又名“中心”）旨在推进肌肉骨骼研究 更好地了解疾病的生物学基础，并开发和测试基于生物学的 我们代表一个由 81 名研究人员组成的研究团体，每年资助 6600 万美元。 我们研究界的优势在于动物模型的使用。 中心及其行政核心是支持动物的开发、实施和评估 我们将通过我们的领导力来实现这一目标。 行政核心将通过一个中心领导该中心。 我们将协调所有中心与我们研究的沟通。 社区和更广泛的 WUSTL 社区我们将参与外展活动和合作伙伴关系。 我们将与其他校园中心和项目一起代表肌肉骨骼研究兴趣。 对研究核心进行指导和监督，以确保它们易于使用、具有成本效益且符合国家标准 通过定期评估利用率和性能，我们将确保核心具有 自 2009 年以来，我们已支持了 343 篇已被引用的出版物。 6687次我们提出了一个多方面的丰富计划来维持和改善环境 WUSTL 的肌肉骨骼研究，并促进下一代的发展 我们将通过试点与可行性 (P&F) 资助计划提供种子。 为有潜力建立更大的赠款提案并提供关键的有潜力的项目提供资金 自成立以来，P&F 为早期研究人员或肌肉骨骼研究新手提供支持。 计划获奖者已因其试点补助金相关工作获得了 21 项外部补助金。 通过研究和教育提供大量交流新想法和发现的机会 最后，我们将通过以下方式支持严格的研究方法。 提供有关小鼠遗传模型的使用以及研究设计和生物统计学的专家咨询。 总之，我们将为我们的研究社区提供必要的支持，以开发、实施和 评估肌肉骨骼生物学和医学的动物模型，同时促进下一代的开发 一代肌肉骨骼研究人员。