Neural Correlates of the Mirror Neuron System

镜像神经元系统的神经相关性

• 批准号: 8701315
• 负责人: Nathan A Fox
• 金额: $ 21.76万
• 依托单位: UNIV OF MARYLAND, COLLEGE PARK
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-07-01 至 2016-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8701315
• 关键词: 7 year old; Adult; Age; Age-Months; Animals; Behavior; Behavior assessment; Behavioral; Brain; Cells; Child; Childhood; Code; Cognitive; Cognitive Science; Development; Electrodes; Electroencephalogram; Electroencephalography; Elements; Ethology; Frequencies; Functional Magnetic Resonance Imaging; Goals; Human; Infant; Instruction; Investigation; Knowledge; Laboratories; Life; Link; Location; Macaca mulatta; Maryland; Measurement; Methods; Motor; Neonatal; Neurosciences; Newborn Infant; Pattern; Perception; Play; Process; Property; Reporting; Research; Research Personnel; Role; Sampling; Scalp structure; Social Behavior; Stimulus; System; Testing; Time; Universities; Videotape; Visual attention; Work; awake; base; cognitive neuroscience; comparative; developmental psychology; infancy; interest; mirror neuron; mirror neuron system; neuroimaging; neuromechanism; neuron development; neurophysiology; nonhuman primate; programs; relating to nervous system; research study; response; skills; social; social cognition

PROJECT SUMMARY (See Instructions): A fundamental issue in cognitive neuroscience is how the brain is able to encode others' actions and intentions. In this perspective one of the most important advances of our knowledge on how these processes can take place in the cortex is the discovery of mirror neurons. The main conceptual breakthrough open by their discovery is that perceptual and motor processes share a common code. The proposed research will investigate, with non-invasive electroencephalography methods, the emergence of the MN system in infancy and young children. It will compare the EEG activity depicted by specific frequency bands in infants with that of children and adults in which the MNs has been widely studied. Acquisition of EEG will be combined with a careful behavioral assessment of subjects in order to test the hypothesis that MNs are at the basis of specific matching behaviors that are important landmarks in the development of perception action relations. We will as well, carry out experiments in non-human primates to identify these EEG rhythms in infant Rhesus Macaque and to link, for the first time, single cell recordings of mirror neurons to the ongoing EEG.

项目摘要（参见说明）： 认知神经科学的一个基本问题是大脑如何能够编码他人的行为和意图。从这个角度来看，我们关于这些过程如何在皮层中发生的知识的最重要进展之一是镜像神经元的发现。主要概念突破由 他们的发现是知觉和运动过程共享一个共同的代码。拟议的研究将通过非侵入性脑电图方法调查婴儿和幼儿中 MN 系统的出现。它将婴儿特定频段描绘的脑电图活动与 儿童和成人的 MN 已得到广泛研究。脑电图的采集将与对受试者进行仔细的行为评估相结合，以检验以下假设：MN 是基于特定匹配行为的基础，而特定匹配行为是感知动作关系发展的重要里程碑。我们将 此外，还在非人类灵长类动物中进行实验，以确定恒河猴婴儿的脑电图节律，并首次将镜像神经元的单细胞记录与正在进行的脑电图联系起来。