Glycoscience Training Program

糖科学培训计划

基本信息

批准号：
10192521
负责人：
I JONATHAN AMSTER
金额：
$ 16.03万
依托单位：
UNIVERSITY OF GEORGIA
依托单位国家：
美国
项目类别：
财政年份：
2014
资助国家：
美国
起止时间：
2014-07-01 至 2022-12-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10192521
关键词：
Training Programs

项目摘要

Abstract/Summary The objectives of the Glycoscience Training Program (GTP) for Predoctoral Students are to train students in research that focuses on both the chemical and biological aspects of glycans and glycoconjugates, and their expression, as they relate primarily to biomedicine. The rationale for this program was highlighted by the National Academies' 2012 study entitled Transforming Glycoscience: A Roadmap of the Future, which demonstrated the great potential that Glycoscience holds for biomedicine, as well as other applications such as bio-energy. Glycoscience involves the study of the function and structure of glycans, the enzymes that regulate their expression, and the genes and regulatory sequences that are involved. The GTP has 22 faculty trainers/mentors from the Chemistry, Biochemistry & Molecular Biology, Infectious Disease, Microbiology Departments and the Bioinformatics Institute. It accepts students from both the Interdisciplinary Life Sciences and Chemistry department portals. Appointments are for 2 years, after which trainees are supported by their trainers. Trainees conform to the requirements of the department/institute of their trainers' appointment. Key activities are a seminar series, annual retreat, monthly breakfast presentations, special classes such as the ASBMB Scientific Communication short course, and biotechnology career development workshops. All trainees are predoctoral students, and we are requesting six full-time appointments, each for a two year duration. The intended outcomes for our students are to progress to a postdoctoral appointment and/or to enter the workforce in the biotechnology industry.

摘要/总结博士前学生糖科学培训计划（GTP）的目标是培训学生研究重点是聚糖和糖复合物的化学和生物学方面及其表达，因为它们主要与生物医学相关。国家统计局强调了该计划的理由科学院 2012 年题为“糖科学转型：未来路线图”的研究表明糖科学在生物医学以及生物能源等其他应用领域具有巨大的潜力。糖科学涉及聚糖的功能和结构的研究，聚糖是调节聚糖的酶表达，以及所涉及的基因和调控序列。 GTP 有 22 名教员培训师/导师来自化学、生物化学与分子生物学、传染病、微生物学系和生物信息研究所。它接受跨学科生命科学和化学的学生部门门户网站。培训期限为 2 年，之后学员将得到培训师的支持。实习生符合聘任培训师的部门/机构的要求。关键活动是研讨会系列、年度静修会、每月早餐演讲、ASBMB Scientific 等特殊课程交流短期课程和生物技术职业发展研讨会。所有学员均为博士前学生，我们请求六次全职任命，每次为期两年。预期结果对于我们的学生来说，他们将晋升为博士后职位和/或进入生物技术领域的劳动力队伍行业。

项目成果

期刊论文数量（29）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

TFCP2 is a transcriptional regulator of heparan sulfate assembly and melanoma cell growth.

DOI：
10.1016/j.jbc.2023.104713
发表时间：
2023-06
期刊：
JOURNAL OF BIOLOGICAL CHEMISTRY
影响因子：
4.8
作者：
Basu, Amrita;Champagne, Rachel N;Patel, Neil G;Nicholson, Elijah D;Weiss, Ryan J
通讯作者：
Weiss, Ryan J

Online Capillary Zone Electrophoresis Negative Electron Transfer Dissociation Tandem Mass Spectrometry of Glycosaminoglycan Mixtures.

DOI：
10.1016/j.ijms.2019.116209
发表时间：
2019-11
期刊：
International journal of mass spectrometry
影响因子：
1.8
作者：
M. Stickney;Patience Sanderson;F. E. Leach;Fuming Zhang;Robert J. Linhardt;I. Amster
通讯作者：
M. Stickney;Patience Sanderson;F. E. Leach;Fuming Zhang;Robert J. Linhardt;I. Amster

Spatiotemporal diversity and regulation of glycosaminoglycans in cell homeostasis and human disease.

DOI：
10.1152/ajpcell.00085.2022
发表时间：
2022-05-01
期刊：
American journal of physiology. Cell physiology
影响因子：
0
作者：
通讯作者：

Glycopeptide epitope facilitates HIV-1 envelope specific humoral immune responses by eliciting T cell help.

糖肽表位通过引发 T 细胞帮助来促进 HIV-1 包膜特异性体液免疫反应。

DOI：
10.1038/s41467-020-16319-0
发表时间：
2020
期刊：
Nature communications
影响因子：
16.6
作者：
Sun,Lina;Paschall,AmyV;Middleton,DustinR;Ishihara,Mayumi;Ozdilek,Ahmet;Wantuch,PaetonL;Aceil,Javid;Duke,JeremyA;LaBranche,CeliaC;Tiemeyer,Michael;Avci,FikriY
通讯作者：
Avci,FikriY

Advancing the Guidance Debate: Lessons from Educational Psychology and Implications for Biochemistry Learning.