ANIMAL CORE

动物核心

• 批准号: 9249646
• 负责人: Kim Elizabeth Saunders
• 金额: $ 24.88万
• 依托单位: OREGON HEALTH & SCIENCE UNIVERSITY
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至 2020-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9249646
• 关键词: Animal Experimentation; Animal Model; Animals; Breeding; Caring; Chronic; Complex; Cost Savings; Development; Disease; Human Resources; Individual; Laboratory Animals; Maintenance; Medicine; Neonatal; Operative Surgical Procedures; Partner in relationship; Pharmaceutical Preparations; Program Research Project Grants; Research; Research Personnel; Research Project Grants; Savings; Schedule; Services; Sheep; Signal Transduction; Time; Tissues; Universities; Veterinarians; Zoonoses; animal care; animal facility; comparative; cost; cost effective; cost effectiveness; design; improved; instrument; member; pregnant; programs; routine care; skills; transmission process

This Program Project Grant designed an animal core to improve cost effectiveness and provide efficiency for the projects in the program. Projects I, II,III will all use sheep through the assistance of the core. The Animal Core provides many advantages for PPG investigators. First, it is much easier to schedule a time-mated breeding program with sheep suppliers, and less expensive by use ofthe "economy of scale." It would be chaotic to have every sheep investigator trying to buy sheep independently. Second, it is often possible to share tissues, and on occasion live animals with other investigators who need similariy instrumented animals for a slightly different purpose. Third, the Department of Comparative Medicine shares animal laboratories within the animal facility for the purpose of chronic experimentation. It would be difficult to overstate the convenience of not having to transport instrumented animals across campus, apart from the otherwise worrisome considerations of the transmission of zoonotic diseases. Fourth, many of the personnel in our Department of Comparative Medicine are highly skilled in the handling of pregnant and neonatal sheep; these skills need to be preserved and an animal core under the directorship of one of the DCM veterinarians is the logical way to do this. Fifth and finally. Dr. Saunders is able to be more involved in each project than is normally possible with the usual arrangement between research projects and DCM veterinary staff. She is an outstanding asset to the University and to the PPG. As a member of the PPG team. Dr. Saunders understands the special needs of each project. Cost effectiveness of this core comes in several forms: First and foremost is coordination in the buying and delivering of animals, 2) sharing personnel for routine care of animals and surgery suite, 3) saving money on veterinary care, 4) saving by buying drugs at lower cost.

该计划项目赠款设计了一个动物核心，以提高成本效益并为 计划中的项目。项目I，II，III都将在核心的帮助下使用绵羊。动物 Core为PPG调查人员提供了许多优势。首先，安排时间合作要容易得多 与绵羊供应商的育种计划，并通过使用“规模经济”来降低价格。这将是 混乱，让每位绵羊调查员都试图独立购买绵羊。其次，通常有可能 共享组织，有时还与其他需要类似仪器的研究者 出于略有不同的目的。第三，比较医学系共享动物实验室 为了进行慢性实验的目的，在动物设施中。很难夸大 不必在校园内运输乐器动物的便利性 人畜共患病传播的令人担忧的考虑。第四，我们中的许多人员 比较医学系在处理怀孕和新生儿绵羊方面具有很高的技能；这些 需要保留技能，并且在DCM兽医之一的董事下进行动物核心是 逻辑方法来做到这一点。第五，最后。 Saunders博士能够比IS更多地参与每个项目 通常，通过研究项目与DCM兽医之间的通常安排。她是一个 大学和PPG的杰出资产。作为PPG团队的成员。桑德斯博士明白 每个项目的特殊需求。 该核心的成本有效性有几种形式：首先是购买中的协调 交付动物，2）共享人员进行动物和手术套房的常规护理，3）节省金钱 兽医护理，4）以较低的成本购买药物来节省。