A New Cage Wash for Laboratory Animal Resources at Iowa State

爱荷华州实验动物资源的新笼式清洗

• 批准号: 10737441
• 负责人: Mary Sauer
• 金额: $ 22.09万
• 依托单位: IOWA STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-07-01 至 2025-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10737441
• 关键词: Accreditation; Animal Experimentation; Animals; Area; Biomedical Research; Canis familiaris; Caring; Cattle; Cavia; Chickens; Collaborations; Communicable Diseases; Dimensions; Educational process of instructing; Electricity; Emergency Situation; Employee; Ensure; Environment; Equipment; Faculty; Family suidae; Felis catus; Ferrets; Future; Goals; Goat; Grant; Hamsters; Health; Human Resources; Iowa; Laboratory Animals; Life; Maintenance; Manuals; Medical Research; Mission; Modeling; Mus; Neurosciences; Oryctolagus cuniculus; Performance; Positioning Attribute; Productivity; Protective Devices; Rattus; Recommendation; Research; Research Personnel; Research Project Grants; Research Support; Rodent; Services; Sheep; Side; Site; Site Visit; Testing; Time; Training; Transportation; United States National Institutes of Health; Universities; Vendor; Veterinary Medicine; Water; Water consumption; Wing; Workplace; animal care; animal facility; animal resource; college; cost; guide for the care and use of laboratory animals; improved; model building; nanovaccine; prevent; repaired; square foot

Project Summary/Abstract The overall objective of this application is to continue the mission of providing high quality healthy animals for research, teaching and testing, assuring care and use of animals consistent with the Guide for the Care and Use of Laboratory Animals, and provide a safe and healthy workplace for personnel who use or care for animals as well as maintaining AAALAC accreditation for the College of Veterinary Medicine. The College of Veterinary Medicine has been AAALAC accredited since 2011. The commitment of the Iowa State University to a high level of animal care is supported by our continued CVM AAALAC Accreditation. This project is for the installation of a new cage washer to replace a 31-year-old unit that has reached the end of its useful life. This cage wash services 30 faculty from various departments and colleges, all of whom have animals in Central or A-Wing animal facilities. During our most recent site visit in 2020, AAALAC stated that “the possibility of entrapment must be eliminated, and in the case of cage/rack washers, ideally an emergency shut-off mechanism that is easily accessible from anywhere inside the machine and which de- energizes the washer when activated should be in place”. Per the AAALAC position statement, it is recommended that de-energizer cords are placed on both sides of the cage wash. Our cage wash is so old that it has been difficult to find a vendor who will retrofit this cage wash with a second de-energizer cord. Our next AAALAC site visit will be in June of 2023, so to keep our AAALAC accreditation and to provide a safe working environment for our employees it is imperative that we purchase a new cage wash that comes with two de-energizer cords. The proposed new cagewash will prevent costly downtime when the current outdated model fails and will reduce operating costs and water usage significantly. These facilities house a variety of species used in teaching and research projects, including swine, dogs, rabbits, cats, hamsters, guinea pigs, cattle, sheep, goats, ferrets, chickens and rodents. The new cage washer will be installed in Central Animal Facility, which services both Central and A- Wing animal facilities. This “green” model will reduce hot and cold-water consumption by 40%. The new cage washer will provide a reliable service for cage washing and will eliminate the cost for repair and days of lost use that occur regularly with the current cage washer. Most importantly, it will ensure proper sanitization of equipment, helping to improve animal health and reduce research variables due to equipment borne fomites. The importance of replacing the 31-year-old current cage washer is significant. The new cage wash will have a longer internal chamber, allowing us to now clean large animal penning that was cleaned manually in the past.

项目摘要/摘要 该应用程序的总体目的是继续提供高质量健康的使命 用于研究，教学和测试的动物，确保与指南一致的动物的护理和使用 照顾和使用实验室动物，并为使用或照顾的人员提供安全健康的工作场所 用于动物以及为兽医学院维持AAAALAC认证。大学 自2011年以来，兽医医学已获得AAAALAC的认可。爱荷华州的承诺 我们持续的CVM AAAALAC认证支持了高水平的动物护理。 该项目是为了安装新的笼子洗衣机来替换已有31年历史的单位 其用途的终结。这款Cage Wash Services来自各个部门和学院的30位教职员工 在中央或A翼动物设施中有动物。在2020年的最新现场访问中，Aaalac 指出“必须消除夹带的可能性，如果是笼子/机架垫圈，理想情况下是 紧急关闭机制，可以轻松从机器内的任何地方访问 当应有激活时，将洗衣机充满活力”。根据AAALAC位置陈述，它是 建议将去碳纤维绳放在笼子清洗的两侧。我们的笼子是如此旧 很难找到一个供应商，他会用第二次去碳器绳索改造这种笼子清洗。我们的 下一次AAAALAC网站访问将在2023年6月，因此要保留我们的AAALAC认证并提供安全 我们员工的工作环境必须购买新的笼子清洗 两个脱启动器线。拟议的新Cagewash将防止当前过时时的昂贵停机时间 模型失败，将大大降低运营成本和用水量。这些设施可以容纳各种各样的 在教学和研究项目中使用的物种，包括猪，狗，兔子，猫，仓鼠，豚鼠， 牛，绵羊，山羊，雪貂，鸡和啮齿动物。 新的笼子洗衣机将安装在中央动物设施中，该设施为中央和A-提供服务 机翼动物设施。这种“绿色”模型将使热水消耗量减少40％。新的笼子 洗衣机将提供可靠的笼子清洗服务，并消除维修成本和损失的天数 使用当前的笼垫圈定期使用。最重要的是，它将确保适当的消毒 设备，有助于改善动物健康并减少由于设备传播的Fomite而导致的研究变量。 取代现年31岁的当前笼垫圈的重要性很重要。新的笼子清洗将有一个 更长的内部腔室，使我们现在可以清洁过去手动清洁的大型动物笔。