Training in the Neurobiology of Neurological Disease

神经系统疾病的神经生物学培训

• 批准号: 8871822
• 负责人: Peter Strick
• 金额: $ 37.67万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-07-01 至 2019-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8871822
• 关键词: Neurobiology; Training; nervous system disorder

DESCRIPTION (provided by applicant): This proposal requests funding for a new postdoctoral training program entitled, "Training in the Neurobiology of Neurological Disease." Briefly, the program has 5 primary goals: 1) To foster understanding of the diseases and syndromes that are of high relevance to the research careers of our trainees; 2) To ensure that trainees are appropriately mentored in their research and that they acquire the professional skills necessary for independent careers in neuroscience; 3) To afford opportunities for innovative research; 4) To attract under-represented minorities to postdoctoral training in neuroscience, and 5) To support training of "special cases" - individuals whose needs differ from those of the typical training fellow. These special cases may include individuals with computational backgrounds who now seek biological training, as well as young scientists who take on projects that require extended time and effort for completion. Our proposal includes a two-year course on the Neurobiology of Disease. The course actively involves academic clinicians and their patients to cover the full spectrum of diseases and syndromes that are of relevance to basic and translational neuroscientists. We also provide trainees with a two-step "Professional Development Series" that is tailored to the specific needs of early- and late-phase postdoctoral fellows in neuroscience. The professional development series includes topics ranging from grant writing to exploring job opportunities and setting up a first lab. Trainees will also be provided with the opportunity to take additional courses, as needed, to fill in gaps in ther background. At the core of every postdoctoral experience is mentored research in an accomplished laboratory. To oversee this experience we have devised a mentoring program that includes regular review of both the trainee and the mentor. Each trainee will have a primary research adviser as well as an individualized Research Advisory Committee. This arrangement will be especially helpful to Early Stage Investigators who will have trainees in their laboratorie for the first time. Our rich neuroscience environment includes 44 primary training scientists and 12 junior faculties specific to this T32. Currently this core training faculty supervises more than 75 postdoctoral trainees (in addition to a substantial number of pre-doctoral students). Nearly 50 of these trainees are eligible for NRSA and/or T32 support. Our neuroscience community includes a broad range of neuroscientists in multiple basic science and clinical departments at the University of Pittsburgh, as well as basic scientists in departments at our sister institution, Carnegie Mellon University. Thus, we believe that the quality and breadth of our faculty, the state-of-the-art facilities, and the unique nature of our training program will enable us to attrac outstanding postdoctoral trainees and provide them with a special experience.

描述（由申请人提供）：该提案请求资助一项名为“神经疾病神经生物学培训”的新博士后培训计划。简而言之，该计划有 5 个主要目标： 1) 促进对与学员研究生涯高度相关的疾病和综合症的理解； 2）确保学员在研究中得到适当的指导，并获得神经科学独立职业所需的专业技能； 3）提供创新研究的机会； 4) 吸引代表性不足的少数群体参加神经科学博士后培训，以及 5) 支持“特殊案例”的培训——需求与典型培训人员不同的个人。这些特殊情况可能包括具有计算背景但正在寻求生物学培训的个人，以及承担需要长时间和精力才能完成的项目的年轻科学家。 我们的建议包括为期两年的疾病神经生物学课程。该课程积极吸引学术临床医生及其患者参与，涵盖与基础神经科学家和转化神经科学家相关的所有疾病和综合征。我们还为学员提供两步式的“专业发展系列”，专门针对神经科学早期和晚期博士后的具体需求。专业发展系列包括从资助写作到探索工作机会和建立第一个实验室等主题。学员将 根据需要，还可以为他们提供参加额外课程的机会，以填补他们的背景空白。 每个博士后经历的核心都是在完善的实验室中进行指导性研究。为了监督这种体验，我们设计了一个指导计划，其中包括对受训者和导师的定期审查。每个学员将有一名主要研究顾问以及一个个性化的研究咨询委员会。这种安排对于首次在实验室培训受训人员的早期研究人员特别有帮助。 我们丰富的神经科学环境包括 44 名主要培训科学家和 12 名专门针对该 T32 的初级教师。目前，该核心培训师负责监督超过 75 名博士后实习生（此外还有大量博士前学生）。其中近 50 名学员有资格获得 NRSA 和/或 T32 支持。我们的神经科学社区包括匹兹堡大学多个基础科学和临床部门的广泛神经科学家，以及我们姐妹机构各部门的基础科学家， 卡内基梅隆大学。因此，我们相信，我们师资的质量和广度、最先进的设施以及培训计划的独特性将使我们能够吸引优秀的博士后学员，并为他们提供特殊的经历。