PGRN Administrative Coordination Hub, ACH (PGRN)

PGRN 行政协调中心，ACH (PGRN)

• 批准号: 8946851
• 负责人: KATHLEEN M GIACOMINI
• 金额: $ 56.41万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-07-15 至 2020-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8946851
• 关键词: Access to Information; Address; Administrative Coordination; Area; Clinical; Collaborations; Communication; Communities; Community Networks; Computerized Medical Record; DNA; Data; Development; Disclosure; Disease; Environment; Genes; Genetic; Genomics; Genotype; Goals; Health; Home environment; Housing; Human; Incubated; Incus; Information Technology; Internet; Interview; Intranet; Japan; Lead; Leadership; Link; Logistics; Medical; Participant; Patients; Pharmaceutical Preparations; Pharmacogenomics; Pharmacotherapy; Publications; Recruitment Activity; Research; Research Infrastructure; Research Personnel; Research Proposals; Resources; Sampling; Science; Scientific Advances and Accomplishments; Site; Taxes; Technology; Translations; base; biobank; built environment; cohort; genome-wide; improved; innovation; interest; lectures; meetings; member; news; novel; outreach; precision medicine; programs; public health relevance; response; sample collection; success; symposium; virtual; web interface; web site

 DESCRIPTION (provided by applicant): Our project aims to establish an Administrative Coordination Hub (ACHPGRN) for the new PGRN that will enhance scientific exchange and expand the boundaries of understanding drug response within the context of precision medicine. The ACHPGRN will employ state-of-the art technologies to support PGRN meetings, communications and will build an infrastructure with a public-facing web interface that focuses on recruiting a diverse new membership, encouraging and incubating nascent collaborations, and providing outreach to broader scientific, medical and public communities. The goal of the ACHPGRN is to catalyze communications and collaborations within the PGRN and between the PGRN and the scientific community at large. To achieve this goal, the ACHPGRN will support activities in three main areas. The first area is focused on scientific meetings. The ACHPGRN will provide high quality, reliable logistical support for meetings and webinars to promote scientific exchange focused on precision medicine. The second area centers primarily on the development of a PGRN website to serve as a virtual home that will include TED-style public presentations, monthly news features, publication links, and podcast interviews that continually provide an up-to-date disclosure of PGRN accomplishments. The third area focuses on catalyzing a collaborative, synergistic network by incorporating networking opportunities at our meetings and an innovative Open Proposals platform. This platform allows research proposals to be developed with broad scientific input from the PGRN community. In conjunction with the third area, the ACHPGRN will facilitate opportunities to access large resources that will enable the collaborative research proposals. In particular, the ACHPGRN will facilitate access to enabling resources established by the existing and new PGRN as well as to two large clinical resources that contain phenotypic information on disease and drug response linked to DNA and other samples. BioBank Japan has over 300,000 DNA samples and the Research Program on Genes, Environment and Health, RPGEH, of Kaiser Permanente now includes samples from 100,000 participants with genomewide genotyping data and extensive phenotypic information from the electronic medical record. Collectively, our hub will provide strong support and leadership for a highly interactive and synergistic network that advances scientific discoveries in pharmacogenomics and precision medicine.

 描述（由应用程序提供）：我们的项目旨在为新PGRN建立一个行政协调中心（ACHPGRN），该中心将增强科学交流并扩大在Precision医学背景下理解药物反应的界限。 ACHPGRN将采用最先进的技术来支持PGRN会议，沟通，并将通过面向公共的Web界面建立基础设施，着重于招募潜水员的新成员资格，鼓励和孵化新生的合作，并为更广泛的科学，医学和公共社区提供外展活动。 ACHPGRN的目标是催化PGRN内部以及PGRN与整个科学界之间的沟通和合作。为了实现这一目标，ACHPGRN将支持三个主要领域的活动。第一个领域的重点是科学会议。 ACHPGRN将为会议和网络研讨会提供高质量，可靠的后勤支持，以促进专注于精确医学的科学交流。第二区主要集中于PGRN网站的开发，以作为虚拟房屋，其中包括TED风格的公开演讲，每月新闻特征，出版物链接和播客访谈，这些访谈不断提供PGRN成就的最新披露。第三领域的重点是通过在我们的会议和创新的开放建议平台上结合网络机会来催化协作，协同网络。该平台允许通过PGRN社区的广泛科学意见制定研究建议。与第三区域一起，ACHPGRN将最喜欢获得大量资源的机会，以实现协作研究建议。特别是，ACHPGRN将喜欢访问现有和新PGRN建立的资源，以及两个大型临床资源，这些资源包含有关疾病和药物反应的表型信息，以及与DNA和其他样品相关的药物反应。日本生物库有超过300,000个DNA样本以及Kaiser Permanente的RPGEH的基因，环境与健康研究计划现在包括来自100,000名参与者的样本，具有全基因组基因分型数据和电子病历中广泛的表型信息。总的来说，我们的枢纽将为高度互动和协同的网络提供强有力的支持和领导才能，该网络推进了科学发现 药理学和精确医学。