The Brief Research in Aging and Interdisciplinary Neurosciences

衰老与跨学科神经科学的简要研究

• 批准号: 8475239
• 负责人: MICHIO HIRANO
• 金额: $ 10.39万
• 依托单位: COLUMBIA UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-05-01 至 2018-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8475239
• 关键词: Academic Medical Centers; Aging; Alzheimer' s Disease; Authorship; Basic Science; Behavioral Research; Biomedical Research; Clinical Research; Clinical Trials; Development; Disease; Education; Educational Curriculum; Epidemiology; Epilepsy; Good Clinical Practice; Institution; Mentors; Motor Neuron Disease; Nervous system structure; Neurologic; Neurologist; Neurology; Neuropsychology; Neurosciences; Parkinson Disease; Patients; Research; Research Methodology; Research Training; Resources; Site; Stroke; Structure; Students; Work; abstracting; career; experience; multidisciplinary; nervous system disorder; neurogenetics; neuropathology; posters; pre-doctoral; programs

DESCRIPTION (provided by applicant): The Department of Neurology at Columbia University Medical Center serves as a rich site for multidisciplinary neurological research, with particular focus on disorders associated with the aging nervous system. In this proposal, the Brief Research in Aging and Interdisciplinary Neurosciences (BRAIN) program, we have developed a comprehensive approach to develop a formal research program for predoctoral students early in developing careers in biomedical, behavioral and clinical research. The work will be collaboratively approached through brief but intensive mentored summer research training experiences for these students, with the potential for subsequent development of a longitudinal research program. The research training will provide opportunities in basic, behavioral and clinical research through ongoing research in the fields of basic neuroscience, neuropathology, neurogenetics, neuropsychology, stroke, Alzheimer disease and related disorders, motor neuron disease, Parkinson disease and related disorders, and epilepsy, as well as neurologic clinical trials treating patients with these disorders. In addition, a comprehensive structured research education curriculum will be given over the course of the intense research experience, with topics including good clinical practice, basic research methodologies, introductions to abstract authorship and poster presentations, and introduction of statistical concepts and approach to analyses, as well as epidemiologic and pathophysiologic reviews of the most common neurologic disorders associated with aging and thus likely to be studied. Our institution has the strongest track record of developing academic neurologists of anywhere worldwide, and such a short-term, intense program will build upon this wealth of resources through hands-on introductions to neurological research, comprehensive review of principles of research, and thus assure the best opportunity for these students to develop research careers in the field.

描述（由申请人提供）：哥伦比亚大学医学中心神经病学系是多学科神经学研究的丰富场所，特别关注与衰老神经系统相关的疾病。在这项老龄化和跨学科神经科学 (BRAIN) 项目的提案中，我们开发了一种综合方法，为博士生在生物医学、行为和临床研究领域早期发展职业生涯制定正式的研究项目。这项工作将通过为这些学生提供简短但密集的指导性夏季研究培训经历来协作完成，并有可能后续开发纵向研究计划。研究培训将通过基础神经科学、神经病理学、神经遗传学、神经心理学、中风、阿尔茨海默病和相关疾病、运动神经元疾病、帕金森病和相关疾病以及癫痫等领域的持续研究，提供基础、行为和临床研究的机会，以及治疗患有这些疾病的患者的神经临床试验。此外，在紧张的研究经验过程中将提供全面的结构化研究教育课程，主题包括良好的临床实践、基础研究方法、摘要作者介绍和海报展示、统计概念和分析方法介绍，以及与衰老相关的最常见神经系统疾病的流行病学和病理生理学综述，因此可能需要进行研究。我们的机构在培养学术神经学家方面拥有世界上最强的记录，这样一个短期、紧张的项目将建立在丰富的资源之上，通过对神经学研究的实践介绍、对研究原理的全面审查，从而确保这些学生在该领域发展研究生涯的最佳机会。