Massachusetts Center for Alzheimer and dEmeNtia behaVIoral reSearch In minOrity agiNg (Mass-ENVISION)

马萨诸塞州阿尔茨海默病和痴呆症少数群体行为研究中心 (Mass-ENVISION)

基本信息

批准号：
10729789
负责人：
Olivia Ifeoma Okereke
金额：
$ 73.58万
依托单位：
MASSACHUSETTS GENERAL HOSPITAL
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-09-01 至 2028-06-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10729789
关键词：
Academic Medical Centers Academy Address Affect Aging Alzheimer&apos s Disease Alzheimer&apos s disease related dementia American Area Asian Behavior Therapy Behavioral Behavioral Research Big Data Methods Biological Biological Markers Biomedical Research Black race Boston Capsicum Caring Cause of Death Centers for Disease Control and Prevention (U.S.)Clinical Trials Collaborations Color Communities Data Data Set Data Sources Dementia Development Discipline Education Elderly Ensure Environment Epidemiology Equity Face Faculty Funding General Hospitals Generations Geriatric Psychiatry Health Health Alliance Health Disparities Research Hospitals Inequity Infrastructure Institution International Intervention Studies Justice Latino Leadership Marketing Massachusetts Measurement Measures Medicine Mentors Methodology Methods Minority Minority Health Research Modeling Neighborhoods New England Ontology Participant Persons Positioning Attribute Prevention Prevention approach Preventive Psychiatry Qualitative Methods Racial Equity Records Research Research Personnel Research Training Resources Satellite Hospitals Science Scientist Site Structural Racism System Testing Training Training Support Translating United States National Institutes of Health Universities Voice behavior change behavioral health behavioral health intervention clinical development clinical implementation clinical translation college community clinic community engaged research community engagement community organizations community setting data complexity digital digital health disability disorder control education research effective intervention ethnic minority evidence base health disparity health equity health inequalities health training high risk human old age (65+)implementation science informal care innovation mHealth medical schools member minority engagement novel programs racial minority recruit segregation skills skills training social social determinants statistics success workforce needs

项目摘要

Massachusetts Center for Alzheimer and dEmeNtia behaVIoral reSearch In minOrity agiNg (Mass-ENVISION) is a proposed new Alzheimer's-related Resource Centers for Minority Aging Research (AD/ADRD RCMAR) that will address the critical need for mentored research training for underrepresented in medicine (UiM) scientists in the development, testing, and implementation of behavioral interventions across hospital and community settings, for racial and ethnic minority older adults with Alzheimer’s Disease and Related Disorders (ADRD) and their informal care partners. There is a dearth of evidence-based behavioral interventions to support minority older persons with ADRD, their informal care partners, and dyads, as well as a critical gap in the number of UiM scientists poised to mitigate this shortage. To address these research and resource gaps, Mass-ENVISION will identify UiM scientists who are committed to ADRD behavioral health and interventions research and will support training and development of independent UiM scientists poised to eliminate health disparities and inequities in ADRD behavioral health. Further, Mass-ENVISION would become the only RCMAR to serve the entire New England region, which is in critical need of this resource. Mass-ENVISION, a collaboration of Massachusetts General Hospital (MGH), Boston University (BU) and Cambridge Health Alliance and their medical school affiliations (Harvard Medical School, BU School of Medicine), university-affiliated hospitals, other Boston and MA- area research centers, satellite hospitals and community clinics, will provide RCMAR Scientists with interdisciplinary, comprehensive training and sustained and tailored mentoring in ADRD behavioral health and interventions research using the revised NIH Stage Model, the Science of Behavior Change, prevention approaches under the Centers for Disease Control disease stage-based (i.e., primary, secondary, tertiary) and the National Academy of Medicine target-based (indicated, selective, universal) frameworks, and the NIA Health Disparities Research Framework. Mass-ENVISION will collaborate closely with other NIA-funded Centers and their investigators, including the Massachusetts Alzheimer’s Disease Research Center (MADRC), Boston University ADRC (BU-ADRC) and Boston Claude D. Pepper Older Americans Independence Center, to translate biological and epidemiological advances as mechanistic targets for ADRD behavioral interventions. Mass-ENVISION will be led by a UiM PI, Dr. Okereke (Director, MGH Geriatric Psychiatry and MGH Psychiatry Center for Racial Equity and Justice), with strong collaborative track records with team members and Core Leads/Co-Leads, who are also from diverse and UiM backgrounds (e.g., Black, Asian, Latino, first generation at college) and have complementary expertise in ADRD, health disparities and health equity research, social and behavioral health, behavioral interventions, implementation science, and interdisciplinary science. Mass-ENVISION will have 4 Cores: Leadership and Administrative, Research Education Component, Data and Analysis, and Community Liaison and Recruitment. Cores will be composed of investigators who are diverse with respect to backgrounds, institutional affiliations in MA and Greater Boston, disciplines, and research and training skills, to facilitate Mass-ENVISION’s success in developing an inclusive research mentoring environment and a diverse biomedical research workforce to advance health equity in ADRD behavioral health.

马萨诸塞州阿尔茨海默病和痴呆症少数群体行为研究中心 (Mass-ENVISION) 是一个提议建立新的与阿尔茨海默氏症相关的少数民族老龄化研究资源中心 (AD/ADRD RCMAR)，该中心将解决迫切需要对发展中的医学（UiM）代表性不足的科学家进行指导研究培训，在医院和社区环境中针对种族和民族进行测试和行为干预实施患有阿尔茨海默病及相关疾病 (ADRD) 的少数民族老年人及其非正式护理伙伴。缺乏基于证据的行为干预措施来支持患有 ADRD 的少数老年人，他们的非正式护理合作伙伴和二人组，以及准备缓解这一短缺问题的密歇根大学科学家数量的严重缺口。这些研究和资源差距，Mass-ENVISION 将确定致力于 ADRD 行为的 UiM 科学家健康和干预研究，并将支持独立的密歇根大学科学家的培训和发展此外，Mass-ENVISION 将成为唯一的解决方案。 RCMAR 为整个新英格兰地区提供服务，该地区急需 Mass-ENVISION 合作。马萨诸塞州总医院 (MGH)、波士顿大学 (BU) 和剑桥健康联盟及其医疗机构学校附属机构（哈佛大学医学院、波士顿大学医学院）、大学附属医院、其他波士顿和马萨诸塞州地区研究中心、卫星医院和社区诊所，将为 RCMAR 科学家提供跨学科、 ADRD 行为健康和干预研究方面的全面培训以及持续和量身定制的指导修订后的 NIH 阶段模型、行为改变科学、疾病控制中心的预防方法基于疾病阶段（即一级、二级、三级）和基于国家医学科学院目标（表明，选择性的、通用的）框架和 NIA 健康差异研究框架将进行合作。与其他 NIA 资助的中心及其研究人员密切合作，包括马萨诸塞州阿尔茨海默病研究中心中心 (MADRC)、波士顿大学 ADRC (BU-ADRC) 和波士顿 Claude D. Pepper 年长美国人独立组织中心，将生物学和流行病学的进展转化为 ADRD 行为干预的机械目标。 Mass-ENVISION 将由 UiM PI Okereke 博士（麻省总医院老年精神病学和麻省总医院精神病学中心主任）领导种族平等和正义），与团队成员和核心领导/联合领导有良好的合作记录，他们也来自不同的 UIM 背景（例如黑人、亚洲人、拉丁裔、第一代大学学生），并且具有互补性 ADRD、健康差异和健康公平研究、社会和行为健康、行为干预、实施科学和跨学科科学将有 4 个核心：领导力和管理、研究教育部分、数据和分析以及社区联络和招聘核心将由以下部分组成。研究人员的背景、马萨诸塞州和大波士顿地区的机构隶属关系、学科、以及研究和培训技能，以促进 Mass-ENVISION 成功开发包容性研究指导环境和多元化的生物医学研究人员，以促进 ADRD 行为健康的健康公平。